2JQ9


Conserved Protein Domain Family
MIT

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pfam04212: MIT 
Click on image for an interactive view with Cn3D
MIT (microtubule interacting and transport) domain
The MIT domain forms an asymmetric three-helix bundle and binds ESCRT-III (endosomal sorting complexes required for transport) substrates.
Statistics
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Aligned: 162 rows
Threshold Bit Score: 48.6806
Threshold Setting Gi: 443922607
Created: 5-May-2019
Updated: 18-Jul-2019
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
2JQ9_A         6 LQKAIDLVTKATEEDKAKNYEEALRLYQHAVEYFLHAIKyE-AHSD---KAKESIRAKCVQYLD----RAEKLKD 72  human
EGD75972      11 LEQASRFAHAAVEMDNLGNYKEAIGLYSHAIQNLDQALA-----DPsfsQSRDSVKQCRASYAA----RVDSLHK 76  Salpingoeca rosetta
EDQ88035       7 LQQASNLAKAAVENDQLGNFKEALDLYERAAHFLELALA-----DPalgAQREQIRTSLNSYRV----RAESLRS 72  Monosiga brevicollis...
EFA76524       4 LQEALELVKKAVALDNAQRTQEAVSMYSLAIEHLRQVID-T-AKDQ---QTRDLIVSKIQEYTK----RVDYLRA 69  Heterostelium album ...
EGC29500       5 LQSALELVHKAVSLDNSGKAQEAISMYSIAIEQLKQASQtt--yDQ---NTKNLIESKILEYQN----RSSFLKS 70  Dictyostelium purpureum
Q54CX7         5 LQSALELVQKAVNLDNNGKAQEAISMYSIAIDHLRQVCNsn--iDQ---STKNLIDSKILEYQN----RSNFLKS 70  Dictyostelium discoi...
Q55GN8         6 LQTGLQLVKSAIDADNQKNYSLACNLYDQAVLNLKLALV-A-EREP---SKNALISSKIEEYSQ----RNKFIKN 71  Dictyostelium discoi...
EEB17482       5 IENAFISSQRAISFDKRGNIQAAIYYYNEAIRYLQIGIN-SnYDDE---NDTTEWKNALEKYQE----RLKTLQE 71  human body louse
EDO77402       9 IDKGFALIKEAVVSDNAKKYPEAYEKYKKGIELISIGL------TS---ETIKGRKENLESYLEkarfRMKQLEQ 74  Giardia lamblia ATCC...
XP_004350507   4 IQGALDLVKKAVSLDNSGKQQEAISVYALAIEHLRQIFDrG-GVDA---QTRELLSQKIQEYTK----RVDYLKS 70  Cavenderia fasciculata
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