4WZX


Conserved Protein Domain Family
MIT

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pfam04212: MIT 
MIT (microtubule interacting and transport) domain
The MIT domain forms an asymmetric three-helix bundle and binds ESCRT-III (endosomal sorting complexes required for transport) substrates.
Statistics
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PSSM-Id: 398061
View PSSM: pfam04212
Aligned: 148 rows
Threshold Bit Score: 45.2183
Threshold Setting Gi: 827343093
Created: 20-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
4WZX_A        22 LLAALEVASAAMaKEEAAGGEQDALDLYQHSLGELLLLLA-AEPPg---RRRELLHTEVQNLMARAEYLKE 88 
Q22143         6 TQSAFELSQKAV-YYDQGKKYEEAIFCYTEAGNQLLRLVQ----Ek---KCLPIFRKNVMECINRAEFLKS 68  Caenorhabditis elegans
XP_003222241   7 EQDAVKFAQLAV-QRDQGGRYQEAVFYYKEAAQALIYAAM----Ag---STLENIPGKISEYLERVQALHS 69  green anole
EGD75972      11 LEQASRFAHAAV-EMDNLGNYKEAIGLYSHAIQNLDQALA----DpsfsQSRDSVKQCRASYAARVDSLHK 76  Salpingoeca rosetta
Q55GN8         6 LQTGLQLVKSAI-DADNQKNYSLACNLYDQAVLNLKLALV-AEREp---SKNALISSKIEEYSQRNKFIKN 71  Dictyostelium discoideum
EGG18013       6 LQTGLQLAKQAV-EADTSKQYTLASQLYEQAILNLKLAIV-SEKDp---SRTALVKTKIEEYTNRNKFIKN 71  Cavenderia fasciculata
EFA76524       4 LQEALELVKKAV-ALDNAQRTQEAVSMYSLAIEHLRQVID-TAKDq---QTRDLIVSKIQEYTKRVDYLRA 69  Heterostelium album PN500
EGC29500       5 LQSALELVHKAV-SLDNSGKAQEAISMYSIAIEQLKQASQtt-yDq---NTKNLIESKILEYQNRSSFLKS 70  Dictyostelium purpureum
Q54CX7         5 LQSALELVQKAV-NLDNNGKAQEAISMYSIAIDHLRQVCNsn-iDq---STKNLIDSKILEYQNRSNFLKS 70  Dictyostelium discoideum...
XP_004350507   4 IQGALDLVKKAV-SLDNSGKQQEAISVYALAIEHLRQIFDrGGVDa---QTRELLSQKIQEYTKRVDYLKS 70  Cavenderia fasciculata
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