6AHR


Conserved Protein Domain Family
Rpr2

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pfam04032: Rpr2 
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RNAse P Rpr2/Rpp21/SNM1 subunit domain
This family contains a ribonuclease P subunit of humans and yeast. Other members of the family include the probable archaeal homologs. This family includes SNM1. It is a subunit of RNase MRP (mitochondrial RNA processing), a ribonucleoprotein endoribonuclease that has roles in both mitochondrial DNA replication and nuclear 5.8S rRNA processing. SNM1 is an RNA binding protein that binds the MRP RNA specifically. This subunit possibly binds the precursor tRNA.
Statistics
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PSSM-Id: 377206
View PSSM: pfam04032
Aligned: 287 rows
Threshold Bit Score: 35.742
Threshold Setting Gi: 209556196
Created: 5-May-2019
Updated: 18-Jul-2019
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
6AHR_K         13 RLNFLYQAAHCvlaqdpenqaLARFYCYTERTIAKRLVL-R-------RDPSV----KRTLCRGCSSLLVPGLTCT---- 76  human
13_pfamImport   1 RFSFLWSSAHRllpt---saaLANHLIASMMQIARTSRA-Q-------LPQSV----LDFICECCGGLLVPSMSADvrv- 64 
EEY54775       15 RFTFLWSSAHTllpt---sptLANHMIATMMQLARSSRA-Q-------LPQPV----LDFICKNCGGLLVPSVSADarv- 78  Phytophthora i...
CBJ29737       44 RMDFLWRASNClrlv---spaVSRIYSDQLRKLCAEYEA-RrpgsgplLPEWV----SDSLCNSCGGILTPGITCRirvr 115 Ectocarpus sil...
EGG14183      209 KLNFLWNACKYnlst---sttYSSLLMNQFQQLEDKWEYnA-------IPPKE----NDSICEKCGSILIPGVNCNvrik 274 Cavenderia fas...
EGC29876       34 NLNYFWVLAHStqpr---npqLGGYYMYKFREMANIKQLrG-------VPTMI----ESRTCSNCGTFLIPGINCRvr-- 97  Dictyostelium ...
Q54IA5         69 NLNYLWSLSHCsqpi---npsLGGYYMYKFREIANIAEMnG-------VPDQI----ETRNCKNCGTFLIPGVNCRvr-- 132 Dictyostelium ...
EIE91350       10 RLDFLFNASHVmfsq---cpsLSRYYMNEFQQTLNEYEL-K-------PTKQI----ERLACQSCGEIAIPGLNTRvni- 73  Rhizopus delem...
EPB85131       24 RLDFLFEAGHTmlse---cpsLSRYYMNEFQNTLTEYEL-T-------AHKPI----ARLSCKSCGQISIPGLNHRiei- 87  Mucor circinel...
EFA83658      191 RLNHLWKAASLmqvg--gatdEARWLMFNFGECAVDNYV-Sg------VPTERkssgGIRICVKCANHLVPGVNCTlrv- 260 Heterostelium ...
6AHR_K         77 ---------------------QRQRRCRGQRW-----------------------------------------------T 88  human
13_pfamImport  65 ------------------vsqSRQSPSNRRlarhqrrahkrlss----------------------tesgrrlicatlsT 104
EEY54775       79 ------------------vpqTLKSPANRRltrqqrciqqqng------------------------sngprlarealsT 116 Phytophthora i...
CBJ29737      116 hrslaspsvkkakaktrvektNTNKCRNEv-------------------------------------------------- 145 Ectocarpus sil...
EGG14183      275 ni--------------kdiggLKRNKLYNREEvinnkln----------------------------------nkiknaI 306 Cavenderia fas...
EGC29876       98 --------------------iiKTDQLSNKSRslistntkeinslefrlkpspqqqqqqqqqqqqqqslsknsnklnnsI 157 Dictyostelium ...
Q54IA5        133 --------------------ivKRSDLSIRSKslisttnleinslsskl-------------kqqsslkqnqskkptnaL 179 Dictyostelium ...
EIE91350       74 ------------------iqkNRREKKKMKKQtk-------------------------------------------nlV 92  Rhizopus delem...
EPB85131       88 ------------------ihkQSRKQNKTKKIvqp------------------------------------------ntI 107 Mucor circinel...
EFA83658      261 ------------------khkSSSGNQSLQQQrksrkd-----------------------------------nktvgfI 287 Heterostelium ...
6AHR_K         89 V--QTCLTCQ 96  human
13_pfamImport 105 IvrVTCHRCR 114
EEY54775      117 IvrVTCHRCQ 126 Phytophthora infestans T30-4
CBJ29737      146 --vTTCLTCG 153 Ectocarpus siliculosus
EGG14183      307 I--KTCTQCK 314 Cavenderia fasciculata
EGC29876      158 T--RVCLKCN 165 Dictyostelium purpureum
Q54IA5        180 I--QFCLQCC 187 Dictyostelium discoideum AX4
EIE91350       93 E--STCLTCG 100 Rhizopus delemar RA 99-880
EPB85131      108 K--STCLTCG 115 Mucor circinelloides f. circinelloides 1006PhL
EFA83658      288 K--IHCNQCQ 295 Heterostelium album PN500
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