4Y66


Conserved Protein Domain Family
Mnd1

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pfam03962: Mnd1 
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Mnd1 family
This family of proteins includes MND1 from S. cerevisiae. The mnd1 protein forms a complex with hop2 to promote homologous chromosome pairing and meiotic double-strand break repair.
Statistics
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PSSM-Id: 335556
View PSSM: pfam03962
Aligned: 127 rows
Threshold Bit Score: 101.07
Threshold Setting Gi: 410077691
Created: 23-Mar-2017
Updated: 23-May-2017
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4Y66_A        15 LLEEMLKRGEI--YSNKTIETL-SK-PTGI-SSMVIKNVLQALVN---ED---LVDTDKIGASTYYWCFASKRSQAARTE 83
gi 74608670   17 ILKFFQDDFAF--YSMKDLEKLiPKkCAGV-SPVIVKELVTAMIEe--DG---VISCEKCGQINVYWCFKNQVVNKIYNA 88
gi 667639798  14 IVNFFKSTPEI--YSIKDLEKKiPK-ECGV-SSMLVPDLLKKLHD---ED---LISVEKCGTSNIYWCFPYNKHHFYSCE 83
gi 367010614  17 ILAFLQNEYSF--YNMKELEKMiPKkCAGV-SPMLVKELVQQMIDe--DG---LICVEKCGNINVYWCFKNQITQKVYDS 88
gi 410730367  38 ILTFLQSTYSY--YTLKELEKLiPKnCKSIsNGILVKDLIKSLLD---DD---LIHMEKCGNINIIWCFKRQVMKEQFII 109
gi 367003900  16 ILNFFQNEYSF--YTIKELEKLiPKkCPSI-SSMVVKELLQAMIDe--DG---LISVEKCGNINVYWCFKNQINQKIYEN 87
gi 403216689  14 VLEWIVNQPSPllFTQKDFEKRyPG-RQ---PSNIVREHLDALVA---DG---VLELSKCGSINVFYYFKNVKWAGIRGD 83
gi 523779568  14 LINILSPQYSF--YDSNELEKIaIK-QAYI-NSMKVKDVINELVS---DD---ILCNEKIGIKNIYYI-PYKSYN----- 77
gi 410077691  14 ikyleglpsTY--FTQKEFEKKcPI---KL-QSSVMKQILDEIVC---EYekyLIGVIKCGNLNIYYIYRNFNRLNIKEE 84
gi 444319174  17 ILNFMQEEFNI--YSMKDLEKLvPKrCPGI-SSMVVKDLIQQLLDedsDG---VIFMEKCGAVNVYWSFKNQSNNKMLKS 90
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4Y66_A        84 LARLQKALEEQTNFIDKATARIEELKV----GREETeers---------------------------------------- 119
gi 74608670   89 AEHLKADKLKIQGEIYSTNDILNITIA----TTRQEefevdgen------------------------------------ 128
gi 667639798  84 TEKVALSIEVFKEENMKKMEQIEKMKV----LKESTpere---------------------------------------- 119
gi 367010614  89 CQRLQAKKEAKEAETIELKAKLKLTSEtdrcERYESpdgiks-------------------------------------- 130
gi 410730367 110 GEKLESSLQVCKEEYSKLENDIEDCLQ----GEYNEyiiddgnng----------------------------------- 150
gi 367003900  88 CTRLQKDIEEKTIVVSDLELRVASTVK----NERAPnftydnkk------------------------------------ 127
gi 403216689  84 LENLSGKVAALTRECEALQTQINSMQE----TRGDFkgkk---------------------------------------- 119
gi 523779568  78 IEQAQIDLEDINNNILSLENNINNNIQ----HRQNSlt------------------------------------------ 111
gi 410077691  85 IDKSNKKVIDIRESIDANKKKLLLYQK----ERKAFkeke---------------------------------------- 120
gi 444319174  91 FNHYQDLIADRKLKIKKLQETFEFEST----HSRKEifsinevkneininntntkdkagtiennattpilenmvnipsni 166
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4Y66_A       120 ----------------sllK---EKLALQVKLEEQRG---TFRDLLK--NDPD---VAQKLRNYTDIAKQEANLWTDNIF 172
gi 74608670  129 ------------fnrnrllE---SKRLLEKAIIQKQR---KLEDLEDirWDSH---KIIDKKREINSLISMIDIATDNME 187
gi 667639798 120 ----------------sllE---EFNTLKRDVLIIEE---ENKHNAE--CSVE---EYEKFIKEIEDMKESINRITDNIF 172
gi 367010614 131 --------------rneqlQ---RNREIEEEIKALQL---EYNKLSQtrWDKE---KIAAKRSMLIRDLQKLETMTDNID 187
gi 410730367 151 ----------gklkrddclR---ELKELDDKLKVSKNnvmELEKFK---WDDE---RISLEKEEKLKDINRLEKLTDNIE 211
gi 367003900 128 ------------ykrlvelD---KLKKLDMQCKTLQN---EYDSLMEnlWDEQ---TLVKKIHLLEKKNDDLNILSDNID 186
gi 403216689 120 ----------------qllL---RQKELERQVASKKL---EISKLRKtrWTPD---DIANKTKEFQSTKAQLESLADNIE 174
gi 523779568 112 -----------------ynN---TIETLEQKIKNIQH---KILQYK----NIK---HRRNITQNTNIIKHNINKIVDNIY 161
gi 410077691 121 ----------------klvKnyhDFSKLHKSLSNQII---NLQKIKL--ENLEnlkLVDDKRDRIENLKKLIHQYNDNIE 179
gi 444319174 167 adnkvltstesdfsrsdkiK---EFQNLQTLKKESTT---AIEKIKStkWTSE---SMSNKKAQLKKDWETLQIVTDNIE 237
                        250       260
                 ....*....|....*....|....*...
4Y66_A       173 CLQKYMLTKLQMDKKTVSTALGITGEFD 200
gi 74608670  188 LLVVYLSKRSCLESSQIRQELSIPSEFQ 215
gi 667639798 173 TIQGHVSSKYGVSRKDFNRNFDVDDEMD 200
gi 367010614 188 IMVDFFRNKYGVDPKSIRQEMEIPDDFp 215
gi 410730367 212 ILVSYLSNKFLIDSKQIRKEFGIPEDFk 239
gi 367003900 187 SIISYLVNKYLVDANDIRKEYGIQEEYk 214
gi 403216689 175 ILVDYLCKKCQVEPSAIRQEFAIPEEFc 202
gi 523779568 162 NIIYYVNRNYHIDRTELSKNFNI-EDID 188
gi 410077691 180 LILDHIARKYNIPNTKLHDELNIPMEL- 206
gi 444319174 238 LLIDFLSKKYAIHSDLIRKELGIPEEFr 265
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