6H9B,1Z5V,5FM1


Conserved Protein Domain Family
Tubulin_C

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pfam03953: Tubulin_C 
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Tubulin C-terminal domain
This family includes the tubulin alpha, beta and gamma chains. Members of this family are involved in polymer formation. Tubulins are GTPases. FtsZ can polymerize into tubes, sheets, and rings in vitro and is ubiquitous in eubacteria and archaea. Tubulin is the major component of microtubules. (The FtsZ GTPases have been split into their won family).
Statistics
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Aligned: 40 rows
Threshold Bit Score: 129.653
Threshold Setting Gi: 70832040
Created: 6-May-2019
Updated: 18-Jul-2019
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
6H9B_A   256 PRIHFPLATYAPVISAE-----K-AYHEQLSVAEITNACFEPANQMVKC-DPR--H-----GKYMACCLLYRGDVVPKDV 321 sheep
Q8IAN7   265 PKCHFLITSYTPITIDKh----I-SNVQKTTVLDVMKRLLHTKNIMVSA-PVR--R-----GMYISILNIIRGETDPTQV 331 Plasmodium falcipar...
Q23FR3   283 PKCHFLMTGYTPISIDRh----I-KTIRKTTVLDVMRRLLQTKNIMVSA-STK--K-----GQYISIMNVIQGEVDASQI 349 Tetrahymena thermop...
P18695   263 PRSHFLLTSYTPFTGDNid--qA-KTVRKTTVLDVMRRLLQPKNRMVSI-NPS--Ks----SCYISILNIIQGEADPTDV 332 Aspergillus nidulan...
P25295   264 PRCHFLLTSYTPFTNQQve--eA-KAIRKTTVLDVMRRLLLPKNQMVSV-NPS--Kk----SCFISILDIIQGEADPADV 333 Schizosaccharomyces...
P42271   264 PQLHFLMTGYTPLMSDCe---tK-TSVRKTTVLDVMRRLLQPKNMMVSA-LTD--Kqs--rQCFVSILNIIQGEVDPSQV 334 fruit fly
P23258   264 PRLHFLMTGYTPLTTDQs----V-ASVRKTTVLDVMRRLLQPKNVMVST-GRD--Rqt--nHCYIAILNIIQGEVDPTQV 333 human
AAX69893 266 PRCHFVCTGYTPTTLDTsn--iQ-SSVQKTSVHDVMRRLLMPKNMMVST-SMK--S-----GCYISLLNLIQGDVDPAQV 334 Trypanosoma brucei
AAA82610 264 PRCHFLMTGYTPLTAENaagqvT-SNIRKTTVLDVMRRLLQPKNIMVST-HTK--SrdianAKYISILNIIQGEVDPSQV 339 Chlamydomonas reinh...
1Z5V_A   264 PRLHFLMTGYTPLTTDQ-----SvASVRKTTVLDVMRRLLQPKNVMVSTgRDRqtN-----HCYIAILNIIQGEVDPTQV 333 human
6H9B_A   322 NAAIATIKTKRSIQFVDWCPTGFKVGINYQPPTVVPGGDlakvqRAVCMLSNTTAIAEAWARLD 385 sheep
Q8IAN7   332 HKGLQRIRDRKLVNFIKWNPASIQVTLAKQSPHVVSQHK-----VCGLMMANHTSISTLFERCv 390 Plasmodium falciparum 3D7
Q23FR3   350 HKSLQRIRERKLANFINWGPASIQVALSKKSPYIETSHK-----VSGLMLANHTSIHTLFEKII 408 Tetrahymena thermophila SB210
P18695   333 HKSLLRIRERRLASFIPWGPASIQVALTKKSPYIQNTHR-----VSGLMLANHTSVATLFKRIV 391 Aspergillus nidulans FGSC A4
P25295   334 HKSLLRIRERRYASFIPWGPASIQVALSKKSPYIKTNHR-----VSGLMLANHTSIASLFKRTL 392 Schizosaccharomyces pombe 972h-
P42271   335 HKSLQRIRERKLANFIPWGPASIQVALPRSSPYVQSAHK-----VSGLMMANHTGISSLFKRAL 393 fruit fly
P23258   334 HKSLQRIRERKLANFIPWGPASIQVALSRKSPYLPSAHR-----VSGLMMANHTSISSLFERTC 392 human
AAX69893 335 HRSLERIRERSP-NFIPWGPASIQVILSKKSPYLDTRHR-----VSGLVMANHTSISSLFQRTL 392 Trypanosoma brucei
AAA82610 340 HKSLQRIRERKQANFIEWGPASIQVALSKKSPYVQTAHR-----VSGLMLANHTSVRHLFNKVL 398 Chlamydomonas reinhardtii
1Z5V_A   334 HKSLQRIRERKLANFIPWGPASIQVALSRKSPYLPSAHR-----VSGLMMANHTSISSLFERTC 392 human
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