2VYE


Conserved Protein Domain Family
DnaB_C

?
pfam03796: DnaB_C 
Click on image for an interactive view with Cn3D
DnaB-like helicase C terminal domain
The hexameric helicase DnaB unwinds the DNA duplex at the Escherichia coli chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a change in the quaternary structure of the protein involving dimerization of the N-terminal domain has been observed and may occur during the enzymatic cycle. This C-terminal domain contains an ATP-binding site and is therefore probably the site of ATP hydrolysis.
Statistics
?
Aligned: 550 rows
Threshold Bit Score: 127.129
Threshold Setting Gi: 378569553
Created: 27-May-2019
Updated: 18-Jul-2019
Structure
?
Program:
Drawing:
Aligned Rows:
Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
2VYE_A                 185 GIPTGFTELD-RMTSGFQRSDLIIVAARPSVGKTA----FALNIA-QN-VA-TKT-NE----N--VAIFSLEMSAQQL-- 247 Geoba...
jgi:Hore_23140         184 GLPTGFISLD-NLIGGFKKGHLNVIAASTSMGKTA----FAINIA--K-NV------LkrnvP--VAIISLEMDAQEI-- 245 Halot...
PRJNA223427:T479_12745 161 GVLTGLLDLD-KLLNGFQDAELTIIAARPSMGKTD----TMNHIA-LK-AG-W---D-----GylPIIFSLEMSRTTL-- 222 Lysin...
hku:LHK_01506          186 GLPTGMAALD-DAIDGLHPGELIVVAGRPSMGKSC----LAEM-I-ARtNAkA---------RraVRFHTYEMPACDV-- 247 Larib...
CBS87047               189 GITTGLADLD-AKLGGLLPG-LYVLGARPSMGKSA----LAFNTI-MLaAArT---------GarVLGFSTEMAAEKV-- 250 Azosp...
jgi:Galf_2031          184 GLLTGVAELD-AITGGLEPGQLIIVAARPSVGKTA----IALNVV-DS-VVtQ---------GksVAFFSLEMTRREI-- 245 Galli...
EDK34001               178 GLATGIKSID-NMTGGLEPGDYVILAARPSMGKSA----MMLEIS-EN-VA---K-Q-----GksVLVFSLEMTKEKL-- 239 Clost...
jgi:Psesu_1150         164 GITTGLQELD-EILGGWHDSDLTFIGGRPAMGKTA----FMLGLA-E-----AAAdS-----GrrVGIVSAEQPAVQL-- 225 Pseud...
Q6FAC9                 183 GVKFNLKHLD-ELLGTVQKGHFCVVGGRPGSGKSTlaqmLALDTAsSF--------------GkgVLFISAEMDQSTL-- 245 Acine...
zhongguo:PM3016_2995   258 GVATGFQRLDdVLFGGLHSG-LYLLAGCASSGKTMlmkqMADHIAlG---------------GtpVVYVSWDMTAFELwa 321 Paeni...
2VYE_A                 248 --VMRMLC-----AEG-NIN---AQNL-----RT-------G-KL-T-PeDW------GKLTM-A-M---------GSLS 284 Geoba...
jgi:Hore_23140         246 --IDRMII-----QES-GVN---GWKY-----NQ-------G-QT-SdE-ED------KRISK-A-L---------DNLH 282 Halot...
PRJNA223427:T479_12745 223 --IDRLIA-----ATG-NFN---RLKV-----RN-------PyEYfTdG-QK------EKWMS-T-L---------GMLD 261 Lysin...
hku:LHK_01506          248 --VMRSAA-----ADM-GIP---LENI-----RK-------A-RM-ErH-EL------DRFMV-F-S---------SRQE 284 Larib...
CBS87047               251 --SRRHLA-----AHT-G---------------IpadrqaqG-DL-TdE-EW------CRLID-A-K---------AELG 287 Azosp...
jgi:Galf_2031          246 --IQRLIA-----LRT-GVP---VSAM-----RA-------GrL--EpE-QW------DLISAsQ-----------GKAN 282 Galli...
EDK34001               240 --MNRLFS-----SLT-KIP---LERI-----KT-------G-EL-T-SpEW------NKLAS-A-A---------NFIC 276 Clost...
jgi:Psesu_1150         226 --GIRRAA-----LAS-GVG---AQAI-----RA-------G-NL-QdE-DW------SKITA-G-I---------SRAR 262 Pseud...
Q6FAC9                 246 --ANRMIS---------ALGlipYHNIhnaelYN----------------GLmkdyadAKAAYqR--------------- 283 Acine...
zhongguo:PM3016_2995   322 rsIARLIGtepqkVLGgTVSpdeVNEAnk--qY-------------------------IPISKmQwTlecspdttmERVL 374 Paeni...
2VYE_A                 285 NAGIYIDD--TP-SIRVSDI-----RAKCRR----LKQE--SGLGMVVIDYLQLIQ-----G--SGr----NrE-NRQQ- 337 Geoba...
jgi:Hore_23140         283 ELPLMISD--ER-GLNVAQI-----RARLRK----FKAQm-GDLGLVIIDYLQMIQlpeehAq------------NTAR- 336 Halot...
PRJNA223427:T479_12745 262 NANIEIDD--RA-GMTVPQI-----RATARK----IIKAnpDKKPVILIDYLQIIRvsnprD-------------NQTQ- 315 Lysin...
hku:LHK_01506          285 GWQIVFDE--DT-GANVDRI-----AMRARR----QKRK--SGLDLLVVDHLHLM---------PY-----R-GdNETR- 334 Larib...
CBS87047               288 ALPIHLDD--TP-GVTVSHI-----RRTCRR----HKRR--HGLDLIIVDHLHRMR--------ASpq--aE-KqGETA- 341 Azosp...
jgi:Galf_2031          283 GQRLHLID--RS-SIGVAYV-----RAAARK----IKRQ--HGLDLVVVDYLGLMR--------G------E-GhNRTQ- 332 Galli...
EDK34001               277 QQKLYFDD--KG-GQTVNEI-----RSKSRK----AKLQ--YDLDLIVIDYIGKIQ-----Gq-G--------E-NRNQ- 326 Clost...
jgi:Psesu_1150         263 DRHLRVFD---RsAVSLDEL-----VSVARK----WKHN--DGLDVLFIDYAQRIT--------VP-----G-A-DRIT- 312 Pseud...
Q6FAC9                 284 -LPIWIQPkqKP---SLSEV-----RSYARRakrrYKE-----LGCIIVDYLQLLR-----------------DpSKKDr 332 Acine...
zhongguo:PM3016_2995   375 N--------------SIERIagiagKT-----------------PVVFIDHLNRIPlalggPvpRVtpaeyQ-T------ 416 Paeni...
2VYE_A                 338 -E-VSEISRSLKALARELEVPVIALSQLSRSVE--QRQDKRPMMSDL------RESGSIEQDADIVAFLYRDDYYNkDSe 407 Geoba...
jgi:Hore_23140         337 -A-VGQIVLQLRNMASELEVPIILISQISRSFT--NRQDKRPVLSDL------RDSGNIEEIADGVIFLYRHAHTSaAAr 406 Halot...
PRJNA223427:T479_12745 316 -A-IGQISWDLKQMAKEFNCPVICLAQLNRSVE--QRQDKRPVMSDL------RDSGNIEQDADVIAFLYRDDYYA--Ke 383 Lysin...
hku:LHK_01506          335 -G-LGEITSSLKRLARDLQIPVVLVAQLNREAG--KNAGRRPTLTDL------RGSGAIEQDADVIVFCHRPHYYDdSRp 404 Larib...
CBS87047               342 -K-ITEITAALCSIWKEFQAPVLLLAQLNRGLE--MREDKRPSMADL------RQSGSIEQDADVIAFLYREEYYLsRTe 411 Azosp...
jgi:Galf_2031          333 -E-IGSLSRGLKGLAKELGVPIIALAQLNRATE--TRQDKRPMLSDL------RDSGEIEQDADIVAMLHREEQHNpAPe 402 Galli...
EDK34001               327 -E-LSRISDALKNLAKELKIPIVVLCQLSRAPE--ARSDHRPMLSDL------RESGSIEQDADIVIMLYRDEYY----- 391 Clost...
jgi:Psesu_1150         313 -E-VSQIARGLKNLARDLNIPVVSLAQVVKGVD--SRPDKRPNAGDL------ANSDELTREADQVLMLYRDEVYNrESp 382 Pseud...
Q6FAC9                 333 fQeVSSISRELKSMAKEFECPVIALVQLNREAEkgKR----PKASDI------KESGQIEQDADQIILV------NpLTd 396 Acine...
zhongguo:PM3016_2995   417 -----SLAYALKQWSREWGGPVVAAI-----------------PSDIgeerlpEG---VEASADVMLLL----------- 460 Paeni...
2VYE_A                 408 ----nK-------------------------NI-----------I--EII--IAKQRNGPVGTVQLAFIKEYNKFVN 440 Geobacil...
jgi:Hore_23140         407 eqaekEg------------------------TE-----------NdtEVI--VAKQRTGQTGAIKLYFEDEF--IRF 444 Halother...
PRJNA223427:T479_12745 384 s--tsK-------------------------NI-----------L--EFI--IAKHRNGPTGTVFASYVKDTGRLSN 418 Lysiniba...
hku:LHK_01506          405 ----aS--------------------------E-----------A--ELI--VAKSRNGPVGTLGVGWRGDFVRFQD 436 Laribact...
CBS87047               412 ----pGrrpdesddkfneryerwtrrsdearGI-----------A--EII--IEKNRDGPIGTIRAHFDGPRTLFSN 469 Azospiri...
jgi:Galf_2031          403 ----wR--------------------------------------GlaDVM--VRKNRNGPLGEMLLTLDGPTMKFSR 435 Gallione...
EDK34001               392 -----Nae---------------------teEKn---------iM--EAI--VTKSRDGKTGTVKLYWDGNTQRIRE 429 Clostrid...
jgi:Psesu_1150         383 ----dK--------------------------------------GvaEIL--IEKNRHGPTGFKRVRFVAETMAFES 415 Pseudoxa...
Q6FAC9                 397 pedstK-------------------------PM-----------GitELI--VVKNRHGKRGAVRVLDYLETCRFRS 435 Acinetob...
zhongguo:PM3016_2995   461 --------------------------------KsqcaseppakvEghPAAlhLMKHRNGPLATVPLRFLDGKARFDE 505 Paenibac...
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap