5Y58


Conserved Protein Domain Family
Ku_C

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pfam03730: Ku_C 
Click on image for an interactive view with Cn3D
Ku70/Ku80 C-terminal arm
The Ku heterodimer (composed of Ku70 and Ku80) contributes to genomic integrity through its ability to bind DNA double-strand breaks and facilitate repair by the non-homologous end-joining pathway. This is the C terminal arm. This alpha helical region embraces the beta-barrel domain pfam02735 of the opposite subunit.
Statistics
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PSSM-Id: 397684
View PSSM: pfam03730
Aligned: 77 rows
Threshold Bit Score: 47.2872
Threshold Setting Gi: 1321391396
Created: 20-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
5Y58_C       467 YNPSDFKNPLLQKHYKVLHDYLLQIET-------TFDENETPNtkkDRMMRED----DSLRKLYYIRNk-iLESEK---- 530 Saccharomyces c...
XP_008116997 474 FKTSKFPNPQFQRLYQCLQHKAFHPDSplppiekHLLDMLEAP---QVVREKCqaplEKVKSLFPLKDa-gKMKEQktaq 549 green anole
XP_014348932 418 FKVNKIPNPQFQRLFQCLQHKAFNPDDplppidtHLREMLERP---QQVTTKCqaplERVKELFPLQDl-gKKKDQktaq 493 coelacanth
XP_007230493 472 FKINSIPNPQFQRLFQCLHHRCVNPGTplppvdpWLKRILDRP---QAVSARCqaplQAMKKCFPLKEv-vRKKEQktsv 547 Mexican tetra
XP_003962032 470 FKPHHIPNPDFQRLFQCLHHRAVNPGTplppmepWLKAILERP---DVINERCqaplEELKRVFPLTEv-eKKKNVktsa 545 torafugu
XP_023192670 467 LKPHHLPNPAFQRHFQCLHHRAVHADSplppmepWLEAALDRP---EVIQERCqaplQEIKKLFPLTEv-eKKKKLktsa 542 southern platyfish
XP_003447481 469 FKPHRIPNPAFQRHFQCLHHRAVSPGTplppiepWLKAALDRP---EVITERCqdplDVLKRKFPLTEv-eKKKKLktsa 544 Nile tilapia
Q9FQ09       451 LKPDLTPNPVLQRFYEYLELKSKSTDAtlppmdgTFKRLMEQD---PELSSNNksimDTFRGSFEVKE---NPKLKkask 524 thale cress
XP_015214714 471 FKVNKMANPQFQRLFQCLHHRALNPSAplppvepWLKEVLERP---QAVTARCqaslKELQGRFPLKEa-iRKKETktsa 546 spotted gar
XP_026301314 435 fLPGCVPNPAIQHRWHILSYRAINPDKpl----pAMENYLKKIleaPLIKERSkshvQNIAQLFRLENidlKAKEKndin 510 honey bee
5Y58_C       531 ---------SEDPiiqrlnkYVKIWN 547 Saccharomyces cerevisiae S288C
XP_008116997 550 hi--fkdntVDGP-------SSQKAK 566 green anole
XP_014348932 494 qi--fkdinEEEP-------DIKKSR 510 coelacanth
XP_007230493 548 d----vfgsGEEP-------NAKKLK 562 Mexican tetra
XP_003962032 546 e---ifgkdSGEP-------DGKKAK 561 torafugu
XP_023192670 543 q---ifgkdSEEP-------DAKKAK 558 southern platyfish
XP_003447481 545 q---ifgkeSEES-------EAKKVK 560 Nile tilapia
Q9FQ09       525 rllrdkpsgSDDEdnrmityDAKENK 550 thale cress
XP_015214714 547 d----ifgnEEEP-------DSKKPK 561 spotted gar
XP_026301314 511 ed--nmqidNSDS-------TKDCNK 527 honey bee
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