3PCO,1PYS,3L4G


Conserved Protein Domain Family
B3_4

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pfam03483: B3_4 
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B3/4 domain
This domain is found in tRNA synthetase beta subunits as well as in some non tRNA synthetase proteins.
Statistics
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PSSM-Id: 335353
View PSSM: pfam03483
Aligned: 304 rows
Threshold Bit Score: 65.275
Threshold Setting Gi: 12229964
Created: 23-Mar-2017
Updated: 23-May-2017
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3PCO_B       212 ACPRYLGRVVKGINvKAPTPLWMKEKLRRCGIRS-IDAVVDVTNYVLLELGQPMHAFDKDRIEGgIVVRMAKEGETLVLL 290
gi 121800126  74 AWREAYKAFGAKPQkTRNSLEALTRR--AATGLPrVNRLTDIYNAISVKHQIPFGGEDLDKYDGaPFLVRATGEEPFQTF 151
gi 121924621  74 AWRETYKAFGAKPKkTMNSLEALLRR--VDNGLPrVNRLTDIYNAISIKHQIPLGGEDLDKYQGaPFLIRAKGDEKFITK 151
gi 81590570   63 CYREAFKKLGMNPNkFPCSVEALTTRVLKNGQIPaINNVVNLVNAMSLKYTLPIGAHDLKKAEGnLKVGFTKGGEPFVPF 142
gi 123174256  63 PYREAFRSLGMNPNkFMSSIEAMTTRVAKNKKLPhINPIVDLGNSISLKYLLPMGAHDMDFRNDdVYVRFSKKGDKFVPF 142
gi 75433049   63 PYREAFRKIGINPNrYPCSAEALFKRLSKGKNLPhINPLVNLNNAISLKYTVLMGTHSLDGVQDdIIMRLTKSGDNFVPL 142
gi 122650565  97 AWHTAYRSFGTNPRrIRPSVDALGRRMVKKGTLPrINPAVDSYNAVSIRHGLPAGAFDLDHVTGdVDIRYADGSETFTPL 176
gi 81600638   64 SWRSVYSEMGVKPSkVLCSFESLYKRVSKGKKVFgINKLVDAYNAVSLRHCLCMGGYDLDNITGsISLRYGRKGEEMLPI 143
gi 494499380  61 VWREAFTKMQLNPNkFLSSVEALHTRVYKSGHLPqINPIVDLVNALSLKYVLPMGAHDLERMTGdMRLRLSRAGDVFTPF 140
gi 499972160  60 AWRRGFSRMGLKPTqYRCASEALLRRFRQEHALPrLHPLIDLCNAISLAFAIPIAVFDTEKIAGdLEVRRAKGDETYLTF 139
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3PCO_B       291 --DGT-EAKL-NADTLVIADHNK-AL-AMGGIFGGEHSGVNDETQNVLLECAFFSPLsitgrarrhglhtdashryergV 364
gi 121800126 152 sgGEP-QTELaAHGEPIWCDNTG-ITcRRWNWRQGPRTALTDDTTRVLFILDALEP-----------------------L 206
gi 121924621 152 sgGEE-VTDHpKPGEVVWCDDGG-VTcRLWNWRQCARTALSDATTNGLFIMDALEP-----------------------M 206
gi 81590570  143 --GQT-EPEYvEKGELVYADEKM-IKtRRWIWRQSEIGKITEESTDIFIPIDGFTD-----------------------C 195
gi 123174256 143 --GET-DVELmEEGELIYSVGDM-VKtRRWIWRQGEEGKITNSSKNIFFPIDGFTD-----------------------A 195
gi 75433049  143 --GKD-EVEEpDEGEVVYAVGSD-VCiRRWTWRQSEHSKITDQTHDVFFPIDGFVD-----------------------V 195
gi 122650565 177 --GEPdTVENpKPGEVVYADSTD-VLtRHWNHRDAHRTRVTEDSTHVAFVLETLHAT----------------------R 231
gi 81600638  144 --GGD-KPIQiDEKVVAYSDATS-ILcVYWNHRDADHTQITNKTKNVVFFVDQIQG-----------------------G 196
gi 494499380 141 --GEQ-QAEVvPPGEIVYADDVE-VRtRRWVWRQGEKAKIVVESRHIFFPIDGFAD-----------------------V 193
gi 499972160 140 --GGE--SEHpEANEVIFADSEDrAHaRRWTNRQSGLSAVRATTRSVLIVAEALHV------------------------ 191
                        170       180
                 ....*....|....*....|.
3PCO_B       365 DPALQHKAMERATRLLIDICG 385
gi 121800126 207 SDDTLQQAADELASALKGLSP 227
gi 121924621 207 DDEKLGAAADELGNELSKLSS 227
gi 81590570  196 NKDAVLKARDEIAEYFEKFFG 216
gi 123174256 196 NLDKVMSAREELAKLLKEIFN 216
gi 75433049  196 NRDAVDKAREDLVGKSKEIFG 216
gi 122650565 232 DGHLLKTAAVELQELLAPHAE 252
gi 81600638  197 DNRA-ELALTDLSKLISRFSK 216
gi 494499380 194 NKADVLAARDELAELVTRLGG 214
gi 499972160 192 ------SAGDDIARLVETAAD 206
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