3T12,3LEQ,3KYE


Conserved Protein Domain Family
Robl_LC7

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pfam03259: Robl_LC7 
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Roadblock/LC7 domain
This family includes proteins that are about 100 amino acids long and have been shown to be related. Members of this family of proteins are associated with both flagellar outer arm dynein and Drosophila and rat brain cytoplasmic dynein. It is proposed that roadblock/LC7 family members may modulate specific dynein functions. This family also includes Golgi-associated MP1 adapter protein and MglB from Myxococcus xanthus, a protein involved in gliding motility. However the family also includes members from non-motile bacteria such as Streptomyces coelicolor, suggesting that the protein may play a structural or regulatory role.
Statistics
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PSSM-Id: 308728
View PSSM: pfam03259
Aligned: 40 rows
Threshold Bit Score: 51.0771
Threshold Setting Gi: 2495837
Created: 15-Jul-2016
Updated: 4-Aug-2016
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
3T12_B  14 VEVLEETLRETGARYALLIDRKGFVLAHkealwapKPPPLDTLATLVASNAAATQALAKLLG-EARFQEEVHQGERMGLY 92  Thermus thermophilus HB8
Q9V8I2   7 LTQVLSQANTGGVENTLLLSQEGALLAYsg----yGDKDARITAAIASNIWAAYEKHGRNAFrEGRLTFVLIDCENGHVA 82  fruit fly
O67683  19 EKVVEKFFTKAEPDLVLIFDKAGRILACkgm--diSDTYSEFISSILSALFFASEELTSMLDkNDEMKDVFYETKNRVFL 96  Aquifex aeolicus VF5
Q9SWQ6   8 DETFKRLQSHKGVLGIIVINAEGIAIRTt-----fDNDLTVQYAALVSHFTVKARSAVRKLDgDNDLKFLRIRSKKHEIM 82  Chlamydomonas reinhar...
Q9DAJ5   5 EETLKRIQSHKGVIGTMVVNAEGIPIRTt-----lDNSTTVQYAGLLHQLTMKAKSTVRDIDpQNDLTFLRIRSKKHEIM 79  house mouse
Q22752   5 EETIRRLQSEKGVVGIIVVDSAGRVIHSt-----iDSDATQSHTAFLQQLCEKTKTSIRELDsSNDLTFLRLRTKKNEIM 79  Caenorhabditis elegans
Q9V9P1   6 EDLLKRYQNYPNVSGIIILDPFAIPIKTt-----mEYTLTVHYAALISTLTYKAAKMITNLDaSNELVTIRLRTKVHEVI 80  fruit fly
Q9VQA6   6 EELLKRFQSMKNVTGIVVVDNDGIPIKTt-----lDYTLTLHYAALMQTVREKARQVVLDLDaTNEFTFLRLRTEQNEVM 80  fruit fly
Q9VJ18   7 QMTFDRLVQLPGVTGAILIDGNGVPVRTn-----lPANVARIYADRMRPLVILARSMVQDLEnGDELSYVRLRTRRQETM 81  fruit fly
Q9W168  32 GDAFVNLFAHRGARDIMILDSHGVPLRSt-----cSQRRTFVFVSNLKPLLFMARNVVRDLDpSNDITFMRIRSNMGEIH 106 fruit fly
3T12_B  93 VDEAGE---HALLVLVF 106 Thermus thermophilus HB8
Q9V8I2  83 ITQVAS----VLLCLYA 95  fruit fly
O67683  97 MARLEK---DFLIGVIS 110 Aquifex aeolicus VF5
Q9SWQ6  83 IAPEFErshEYYLVVVQ 99  Chlamydomonas reinhardtii
Q9DAJ5  80 VAPDKE---YLLIVIQN 93  house mouse
Q22752  80 IAPDKD---HVIMVIKD 93  Caenorhabditis elegans
Q9V9P1  81 VLPSEN---YIIIVVQN 94  fruit fly
Q9VQA6  81 LCPQED---YFIMVIQS 94  fruit fly
Q9VJ18  82 VATENE---HTIILIQD 95  fruit fly
Q9W168 107 MTLGTD---FILIVVQK 120 fruit fly
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