Conserved Protein Domain Family
PRA1

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pfam03208: PRA1 
PRA1 family protein
This family includes the PRA1 (Prenylated rab acceptor) protein which is a Rab guanine dissociation inhibitor (GDI) displacement factor. This family also includes the glutamate transporter EAAC1 interacting protein GTRAP3-18.
Statistics
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PSSM-Id: 335264
View PSSM: pfam03208
Aligned: 175 rows
Threshold Bit Score: 50.1843
Threshold Setting Gi: 721660747
Created: 22-Mar-2017
Updated: 23-May-2017
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75173367   31 SGLATRRPWKQMLd-lGSFNFPR--KLATVITRIRANTVYFQTNYTIVVLFSVFLSLI-WNPFSLLVLLALLGAWLFLY- 105
gi 122022658  55 RQLAMVRPWKEFFd-rECFLPPS--GLSESLSRLNRNINHYYHNYMIMAMLCSSYVLL-LNPAFSLCVALTLAMWWFVG- 129
gi 122100392  61 QQLNRVRPWSQFFd-rEQFASPE--GFGDAVSRLRCNVVHFYHNYFVVALLGSLIVLI-VNPMFSICMFLMLLMWAYTH- 135
gi 485218460  37 screkIRPWKEFFn-tSNYKAPP--NFSRLIKRAVNNINHFQGNYVIVSLVLMAYCLL-TSPLLLISIFVSLIACYILS- 111
gi 242017460  43 qkreNVRPWTTFIn-tNNFKTPS--SLPRLSKRIMRNIEYFQSNYLFVFVGLIIYCLL-TSPLLLLAVAVSLGVGYKLS- 117
gi 241111175   1 -mVASIQPWRPFLd-tAKLSVPK--TAQELGHRVHSNLEKYRSNYELVFVAFFVCCVL-ASP-GLFVGVVGCAGLCWVL- 73
gi 299470747  51 lRLKEMKGWGEFF---ARFKAPRawNTKVLDERLTTNFLHYRGNYSVVAAGLLVVGII-SNPYVLLALLCCALLLTFLF- 125
gi 675861218  16 QWKKNIRPVKDFVn-kSRYDFPT--SYDNGIKRFVANIDYFYSNYLLVVIFFIAVAIL-TTPALLFVVLSSLSLSLFLFk 91
gi 472377590  37 RRRATIRPWGSFVd-qRRFSRPR--NLGELCQRLVRNVEYYQSNYVFVFLGLILYCVV-TSPMLLVALAVFFGACYILY- 111
gi 721660747  26 gvrAARRAASRFApgaSAFSAAA--DAEAAAVRAVRNLRTFAPHYAALQWALLLASLSaTGHRSCVLALMAASKGVLLL- 102
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 75173367  106 F-------LR----D--EPLT-VFDREID--HRIVLIIMSVITLSILFLTDAKLNIAVAIVAGALAVLSHAAVRKTEDLF 169
gi 122022658 130 TkrvealeTN----S--NHFI-VLNRKIT--FSQAYLFIAIFAGISFFITNGSSVVFWLVLSSVGVVVVHAVLRKPQIEe 200
gi 122100392 136 KkqmeaaeTN----V--NHLL-IGNYEIS--FSKAYILISIFGIISFFLFNGSSVMFWMFFASLGVATVHAVLRKPHSEN 206
gi 485218460 112 Lr------NA----E--KKLK-IGSKEIS--LNQQYSLVGMLSLPLYYWAGVGQAVFWVLGATCFVVSLHAGMYSIEDvl 176
gi 242017460 118 K-------RQ----N--EKKTiILGHELT--LAQQYGVVAICSIPLFIWAGAGAAVFWVIGASFFIITLHAAFfnieavv 182
gi 241111175  74 K-------VHqddeS--APIL-NTGVVLT--KAQRAACAASVVLPILYVADGWTAAVWSLAACVLVSLLHAGFHEaavsq 141
gi 299470747 126 P-------TG----EprRAVR-VGDRTLE--RQERLAAAVIGASCILGLTGAWYILLFYGGAGVLLCLLHGVFRPRSIgs 191
gi 675861218  92 K-------NT----D--RNVK-IISHNIAlnTTQQLRIVAVVSFVFFWLVGGTAALSWVVCMSVLFITAHAIAFNKEkmp 157
gi 472377590 112 Lr------TL----Q--SKFV-LFGREVT--PAHQYALAGGVSFPFFWLAGAGSAVFWVLGATLVVIGSHAAFH--QTEA 174
gi 721660747 103 LgclkfgpAQsfpgS--ALL-----------RRRIMVILAVLVFAGLAAAGAVSSVMAALGVGVPLVVLHASFRVRDDLE 169

                 ..
gi 75173367  170 QT 171
gi 122022658 201 qp 202
gi 122100392 207 EL 208
gi 485218460 177 te 178
gi 242017460 183 ks 184
gi 241111175 142 es 143
gi 299470747 192 kt 193
gi 675861218 158 qh 159
gi 472377590 175 VD 176
gi 721660747 170 AP 171
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