5YLZ,1G7S,5YT0,5A9W,2H5E,3JB9,2EFG,3J0E,6NOT,3CB4,2YWE,3VMF,3P27,4CRN,3J5Y,2DCU,1S0U,6QG6,1XB2,2C77


Conserved Protein Domain Family
GTP_EFTU_D2

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pfam03144: GTP_EFTU_D2 
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Elongation factor Tu domain 2
Elongation factor Tu consists of three structural domains, this is the second domain. This domain adopts a beta barrel structure. This the second domain is involved in binding to charged tRNA. This domain is also found in other proteins such as elongation factor G and translation initiation factor IF-2. This domain is structurally related to pfam03143, and in fact has weak sequence matches to this domain.
Statistics
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PSSM-Id: 397315
View PSSM: pfam03144
Aligned: 191 rows
Threshold Bit Score: 32.6182
Threshold Setting Gi: 73915356
Created: 11-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
5YLZ_C  481 AEWSLVRIYSGLLKRGDTVRILdtsqsEsrqkrqLHDISKTETSNEDEDEDdetpsceveeigllggryvypVHEAHKGQ 560  Saccharomyces cerev...
P53530  248 GVVTYVRVVDGKISPRERIAMMst-gaTyel-leVGIVSPEPKASAGLGV------------------------GEVGYL 301  Mycobacterium lepra...
Q9RDC9  222 GVVTYVRVIDGQLNKRERIRMMstgatHe-----LLEIGTNSPEMLSADGL---------------------GVGEVGYL 275  Streptomyces coelic...
P75498  206 GVVCFIRIFEGSLKLNDKIRFArs-nsVy----qIVELGIKNPFFEKQDVL---------------------KAGEIGWF 259  Mycoplasma pneumoni...
O51115  213 GVVVHFRIFEGQIKMGDKIRLMhtnseHl-----IEEIGIFKISLERKDTL---------------------EAGDVGYF 266  Borreliella burgdor...
Q9X1V8  224 GVIVHVRLFDGQVKPGDKIMTFsn-kkVy----eVQEVGVFLPEMEPVDSL---------------------SAGEVGYI 277  Thermotoga maritima...
2YWE_A  207 GAVAFVRIFDGEVKPGDKIMLMstgkeYe-----VTEVGAQTPKMTKFDKL---------------------SAGDVGYI 260  Aquifex aeolicus VF5
Q9VRH6  299 GALNLIYVLNGKLEQNQDIQSLatkkvYs-----VKSISVLRPAECPVPDV---------------------SAGQVGLI 352  fruit fly
P34617  236 GAIAHIMVKEGSVKKGDKIQSYqn-ekVy----dVSEVGVMRPEMVKCTEL---------------------RAGQVGYL 289  Caenorhabditis elegans
O13869  258 GVIGLVRIMEGFIKKGGKVMSVntgrkYe-----VQQVGIMYPDMTEVSRL---------------------RAGQVGYI 311  Schizosaccharomyces...
5YLZ_C  561 IVLIKGISSaYIKSATLY 578  Saccharomyces cerevisiae S288C
P53530  302 ITGVKDVRQs-KVGDTVT 318  Mycobacterium leprae TN
Q9RDC9  276 ITGVKDVRQs-KVGDTVT 292  Streptomyces coelicolor A3(2)
P75498  260 SAGIKKLRD-VTVGDTIV 276  Mycoplasma pneumoniae M129
O51115  267 IAGIKNISD-VKIGDTVT 283  Borreliella burgdorferi B31
Q9X1V8  278 IAGIKEVSDa-RVGDTIT 294  Thermotoga maritima MSB8
2YWE_A  261 AASIKDVRD-IRIGDTIT 277  Aquifex aeolicus VF5
Q9VRH6  353 ACNMRNSKEs-IVGDTIH 369  fruit fly
P34617  290 VCNMRTVNEa-VVGETLF 306  Caenorhabditis elegans
O13869  312 IWNMKNIDEa-IVGDTYS 328  Schizosaccharomyces pombe 972h-
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