Conserved Protein Domain Family
Glyco_hydro_57

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pfam03065: Glyco_hydro_57 
Glycosyl hydrolase family 57
This family includes alpha-amylase (EC:3.2.1.1), 4--glucanotransferase (EC:2.4.1.-) and amylopullulanase enzymes.
Statistics
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PSSM-Id: 308604
View PSSM: pfam03065
Aligned: 22 rows
Threshold Bit Score: 204.933
Threshold Setting Gi: 81556513
Created: 17-Jul-2016
Updated: 4-Aug-2016
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Q9HLU6  262 AIIYNDHQPLYKIVG-------SNNYVLPWTEVHATSEYI----------EQALIAHMFpQ----INVTYELSGSLLYQL 320  Thermoplasma acidop...
Q8YXA5    8 AFIWHQHQPLYKSPGsslstpsSQQYRLPWVRLHGTKDYL----------DLILILEKYpK----LHQTVNLVPSLILQL 73   Nostoc sp. PCC 7120
Q55545    8 AFVWHQHQPCYQSYGmvg--ngHGYYQLPWVRLHGTRDYG----------GLIKLWARYpS----LHQTVSFTPCLLAQL 71   Synechocystis sp. P...
O83182   12 AFAAKLTEACVQSLHae----------------hDPSQYQ----------AFFSGLCRHeQ----LPLTVHMTGSFFQFI 61   Treponema pallidum
P09961    8 SLGIHNHQPv------------------------GNFDFVierayemsykPLINFFFKHpD----FPINVHFSGFLLLWL 59   Dictyoglomus thermo...
O32450    7 IFGIHNHQPL------------------------GNFGWVmesayersyrPFMETLEEYpN----MKVAVHYSGPLLEWI 58   Thermococcus kodaka...
O57932    7 IFGVHNHQPL------------------------GNFEWIikrayekayrPFLETLEEYpN----MKVAVHISGVLVEWL 58   Pyrococcus horikosh...
Q9KD04    7 SLVLHAHLPYVRHQEedr-leeRWLFEA------MSETYI----------PLLWALEKLpVk---HAVTISFTPPVMEML 66   Bacillus halodurans
Q8U136    6 TFVLHSHIPYVRKHGkwp-fgeEWVFEA------IAETYI----------PLLMEFEKLrNkgvnFKLVISFSPVLLEQL 68   Pyrococcus furiosus
O50094    6 TFVLHTHIPYVRKHGkwp-fgeEWLFEA------MAESYI----------PLLMELEKLkErgvrFELVISFTPVLMEQL 68   Pyrococcus horikoshii
Q9HLU6  321 VNISTDPyynntfiqyafipyselnttqnqsllanitadyfsipsyvykldepasneylelhniwasggklskaqfedak 400  Thermoplasma acidop...
Q8YXA5   74 EDYIAGTafdpylkasltpteqltqqqrefiiqhffdanhhtlidphpryaelyyqrqekgqswcl---------anwql 144  Nostoc sp. PCC 7120
Q55545   72 EDYAQGLaidrhlaltlspveklsleqkveilttffeanprtqifpqhryqqlyeqrqrqgidwcis--------hwqpq 143  Synechocystis sp. P...
O83182   62 QKKNSPY------------------------------------------------------------------------- 68   Treponema pallidum
P09961   60 EKNHPEY------------------------------------------------------------------------- 66   Dictyoglomus thermo...
O32450   59 RDNKPEH------------------------------------------------------------------------- 65   Thermococcus kodaka...
O57932   59 ERNRPEY------------------------------------------------------------------------- 65   Pyrococcus horikosh...
Q9KD04   67 SDPLVQTrylnhlenteqllkkeekrtndqrt------------------------------------------------ 98   Bacillus halodurans
Q8U136   69 NDEYMKKefekyitrklelmkedltkytndql------------------------------------------------ 100  Pyrococcus furiosus
O50094   69 ADEYIKRefekymerklksmeedlerfkdekl------------------------------------------------ 100  Pyrococcus horikoshii
Q9HLU6  401 vlwflydistplvegqlgstwmnstiwamhnqtsfsqrdlteilhyskwltgqvIPAFRNdmlGNDLGSdnVELFTSPFY 480  Thermoplasma acidop...
Q8YXA5  145 adysdllawhnlawidplfwddpeiaawlqqgrnftlgdrqriyskqrdilsriIPQHRK---MQESGQ--LEVTTTPYT 219  Nostoc sp. PCC 7120
Q55545  144 dfsdllawhnliwfdaltiaedrdvrdwyfrqksftlgdrqriiskqrqiiqgiIPLHRQ---LQESGQ--LEIITSPYG 218  Synechocystis sp. P...
O83182   69 ------------------------------------------------------PYLINN---LLGSKR--LELLSGGFY 89   Treponema pallidum
P09961   67 ------------------------------------------------------FEKLKI---MAERGQ--IEFVSGGFY 87   Dictyoglomus thermo...
O32450   66 ------------------------------------------------------LDLLRS---LVKRGQ--LEIVVAGFY 86   Thermococcus kodaka...
O57932   66 ------------------------------------------------------IDLLKS---LIKKGQ--VELVVAGFY 86   Pyrococcus horikosh...
Q9KD04   99 -----------------------------qnlvqfykqryeklkatflqwdrnlLIGFRS---LMENEQ--CTLMTSAAT 144  Bacillus halodurans
Q8U136  101 -----------------------------kkaiaymityfedvyrywkeingdiIGKFRE---FQEAGY--LEIITSAAT 146  Pyrococcus furiosus
O50094  101 -----------------------------reainfmigyfkdvysywksidgniLGKFRE---LQDEGY--VEVITSAAT 146  Pyrococcus horikoshii
Q9HLU6  481 HPLTPLLLAnnisgpdg-----tiqkasyYSDVLAQMNISRGQFHELFGQWPSGMYAPEFTVSY---------------- 539  Thermoplasma acidop...
Q8YXA5  220 HPILPLLADtnsgrvavpnmalpesrfqwSEDIPRHLRKAWELYTERFGQEPKGLWPSEQSVSP---------------- 283  Nostoc sp. PCC 7120
Q55545  219 HPILPLLADtniartiqaalalpdprfcwSEDGIRQLQQGKQYYRSTFGRESRGLWPPGLAVSP---------------- 282  Synechocystis sp. P...
O83182   90 QPYLPLLPQ---------------------ADVISQIELLTSTLREHVIKRPRGCFLEASAWSA---------------- 132  Treponema pallidum
P09961   88 EPILPIIPD---------------------KDKVQQIKKLNKYIYDKFGQTPKGMWLAERVWEP---------------- 130  Dictyoglomus thermo...
O32450   87 EPVLASIPK---------------------EDRIVQIEKLKEFARN-LGYEARGVWLTERVWQP---------------- 128  Thermococcus kodaka...
O57932   87 EPILVAIPE---------------------EDRVEQIKLSKGWARK-MGYEARGLWLTERVWEP---------------- 128  Pyrococcus horikosh...
Q9KD04  145 HAFFPYLKT--------------------KEAIRAQVRHGIACFEQHFGKKPLGFWLPECAFSP---------------- 188  Bacillus halodurans
Q8U136  147 HGYLPLLGR--------------------DEAIEGQIANAIKTYEKYFQRRPRGMWLPECAYRPdgywrspstgevvwrk 206  Pyrococcus furiosus
O50094  147 HGYLPLLGR--------------------DEAIEAQLLNGIKVYEKYFGRKPRGIWLPECAYRPdglwkspstgevkwrk 206  Pyrococcus horikoshii
Q9HLU6  540 QMMQAINESGAIWSNSAEATLrasginalgydfgnGGNVSQMMNLYTPYIALgpnntsVYMFFRDGYISNNWAFNYGNLP 619  Thermoplasma acidop...
Q8YXA5  284 DILPYIIKQGFQWICSDEAVLgwtlkh--ffhrdgAGNVQQPELLYRPYRLAtpa-gdLAIVFRDHRLSDLIGFTYGAMP 360  Nostoc sp. PCC 7120
Q55545  283 AMLQTVAQLRFEWLCADESVLaq----------slSTSAERSVWLNSVYRVPted-geLAMVFRDQQLSDLISFHYGRYS 351  Synechocystis sp. P...
O83182  133 ALIPSLVKAGMEYCLLD----------------------------YRLFEASdmpatkPAVL--EDSSKCLVALPYRELT 182  Treponema pallidum
P09961  131 HLVKYIAEAGIEYVVVDDAHF--------------FSVGLKEEDLFGYYLMEeqg-ykLAVFPISMKLRYLIPFA----- 190  Dictyoglomus thermo...
O32450  129 ELVKSLRAAGIDYVIVDDYHF--------------MSAGLSKDELFWPYYTEdgg-evITVFPIDEKLRYLIPFR----- 188  Thermococcus kodaka...
O57932  129 ELVKTLREAGIEYVILDDYHF--------------MSAGLSKEELFWPYYTEngg-eaIVVFPIDEKLRYLIPFR----- 188  Pyrococcus horikosh...
Q9KD04  189 GVDRILFEEGIRYTFVDEHAVltadptphkgssapIYSPHG-----------------IALFPRHTELSAKVWSSTLGYP 251  Bacillus halodurans
Q8U136  207 GIEHFLKKYGIDYFFVESHLIdegpatskygeilpEKTKKSTLRPYflk-------ngIAVFARNRETGIQVWSADIGYP 279  Pyrococcus furiosus
O50094  207 GIEHFLKKFGIEYFFVESHLIdkgpvslrygnilpAKTKRSTLRPYflk-------ngIAVFARNRETGIQVWSAKVGYP 279  Pyrococcus horikoshii
Q9HLU6  620 TWTAVDNIINYLkg-vySAIPAQYHQRTLVTIGIDGENWMf--mSPFAEDGVPFLEDLYTaleQNST------------- 683  Thermoplasma acidop...
Q8YXA5  361 AKQAAADLVGHLqaiakMQRERPSEQPWLVTIALDGENCW----EFYPQDGKPFLEALYQ---SLSNe------------ 421  Nostoc sp. PCC 7120
Q55545  352 PAQAAEDLMARLl---aRRPQAENGQPRLVTIALEGDRTW----NGYENNGFGFLQQFYQqceQLGRq------------ 412  Synechocystis sp. P...
O83182  183 IDTPAETFYa------qLVARYGDTPGTVLIFMLPLDCYQk--lFFTHDNASTWFKTFIQyvqKPNSpfrlthtgeiyke 254  Treponema pallidum
P09961  191 ---DPEETITYLd------KFASEDKSKIALLFDDGEKFGlwpdTYRTVYEEGWLETFVS---KIKEn------------ 246  Dictyoglomus thermo...
O32450  189 ---PVDKTLEYLh------SLDDGDESKVAVFHDDGEKFGvwpgTYEWVYEKGWLREFFDrvsSDERi------------ 247  Thermococcus kodaka...
O57932  189 ---PVNETLEYLh------SLADEDESKVAVFHDDGEKFGawpgTHELVYERGWLKEFFDrisSDDKi------------ 247  Pyrococcus horikosh...
Q9KD04  252 GDVDYREFYRDIaydreWDYIKPHVHKDGIRIDTGLKYHRi---TGHTEEKDLYVREWAEkrvQEHAn------------ 316  Bacillus halodurans
Q8U136  280 GDFWYREFHKKAe-------------------KSGGQYWRvtskEIDLGGKEPYVPEKAMervEEHAr------------ 328  Pyrococcus furiosus
O50094  280 GDPWYREFHKRAe-------------------KSGGQYWRvt-gTKDLGAKEPYEPEKAMervNEHAk------------ 327  Pyrococcus horikoshii
Q9HLU6  684 ------YIHTVTPE--QFINQIKNEGIKLPVIQHla-------------------------tAGWNsgngeaapyqsNIY 730  Thermoplasma acidop...
Q8YXA5  422 -----pHIKLVTVS--EFIEEFPATATIPAEQLHs---------------------------GSWV-----------DGS 456  Nostoc sp. PCC 7120
Q55545  413 -----gLLQLVTVS--KFIDQFPPTQVLAQQNGIpip-----------------------liGSWN-----------RGN 451  Synechocystis sp. P...
O83182  255 ppvcfgYIASNMVRndVLLHKTAKQLIICSTHARllyakmmyvhniamqikgdkqrkhhalsELWKaeqgvffissdRGY 334  Treponema pallidum
P09961  247 ------FLLVTPVNlyTYMQRVKPKGRIYLPTAS-------------------------------------------YRE 277  Dictyoglomus thermo...
O32450  248 -----nLMLYS-----EYLQRFRPRGLVYLPIAS-------------------------------------------YFE 274  Thermococcus kodaka...
O57932  248 -----nLMLYS-----EYLSKFRPKGLVYLPIAS-------------------------------------------YFE 274  Pyrococcus horikosh...
Q9KD04  317 -----hFIGAIHHEidQHGGQNFPPYVMVTPFDAel-------------------------fGHWWfegpewiealyEQG 366  Bacillus halodurans
Q8U136  329 -----hFISLVSSLleEFKKKEGEYGIVVAPYDTel-------------------------fGHWWfegvkwlgkvlELA 378  Pyrococcus furiosus
O50094  328 -----hFIGLVLSIleSFESTEGEKGIVVAPYDTel-------------------------fGHWWfegakwlsrvlELA 377  Pyrococcus horikoshii
Q9HLU6  731 LTQWSGDSVQDFYWQAL 747  Thermoplasma acidophilum
Q8YXA5  457 FTTWIGDPAKNRAWDYL 473  Nostoc sp. PCC 7120
Q55545  452 FSKWIGQPSQNQAWDYL 468  Synechocystis sp. PCC 6803
O83182  335 ASAGSAQRTAYKYLLTA 351  Treponema pallidum
P09961  278 MMEWVLFPEAQKELEEL 294  Dictyoglomus thermophilum H-6-12
O32450  275 MSEWSLPARQAKLFVEF 291  Thermococcus kodakarensis KOD1
O57932  275 MSEWSLPARQAKLFFEF 291  Pyrococcus horikoshii OT3
Q9KD04  367 ADR-VSFITPELYLQRH 382  Bacillus halodurans
Q8U136  379 EKLGIKTTTISEFLDNF 395  Pyrococcus furiosus
O50094  378 ERSGIKTVTISNFLDEF 394  Pyrococcus horikoshii
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