4RH7,3VKH


Conserved Protein Domain Family
Dynein_heavy

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pfam03028: Dynein_heavy 
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Dynein heavy chain and region D6 of dynein motor
This family represents the C-terminal region of dynein heavy chain. The chain also contains ATPase activity and microtubule binding ability and acts as a motor for the movement of organelles and vesicles along microtubules. Dynein is also involved in cilia and flagella movement. The dynein subunit consists of at least two heavy chains and a number of intermediate and light chains. The 380 kDa motor unit of dynein belongs to the AAA class of chaperone-like ATPases. The core of the 380 kDa motor unit contains a concatenated chain of six AAA modules, of which four correspond to the ATP binding sites with P-loop signatures described previously, and two are modules in which the P loop has been lost in evolution. This C-terminal domain carries the D6 region of the dynein motor where the P-loop has been lost in evolution but the general structure of a potential ATP binding site appears to be retained.
Statistics
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PSSM-Id: 335192
View PSSM: pfam03028
Aligned: 473 rows
Threshold Bit Score: 245.119
Threshold Setting Gi: 965975630
Created: 25-Mar-2017
Updated: 23-May-2017
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
4RH7_A       2757 P----SWIDqERSWAvAT--LKIaLP-SlYQ--T--LC-----Fe-dA--ALWRTYYNNSMCeq----efPsilakKV-- 2811
Q23DR0       3841 eqllesKLT-KQQLK-LL--EDIstntteFS--A--LLp---dVn--RneSSWVDFILSETPed----qvPsdwapQq-n 3902 Tetrahymena t...
A0D7F8       3810 ntflqgKLS-IQQLK-QL--EGItqqnqtFN--R--LId---nLn--KneDRWLNFLNDEAPen----diPtqwynEVqr 3872 Paramecium te...
XP_002604212 4430 arkpfdWML-DDQYN-NL--QVLavyyqwFQdaFdkLPkdgreM-------PWRTLCENDKPela---alPd----KMdd 4491 Florida lancelet
EKC41076     4591 mkkpfdWMH-DDQFH-NL--QVLathfewFQekFerMPkdgreM-------EWRMLCDNVEkepe-nmplPd----KMds 4654 Pacific oyster
XP_015211261  407 aknpfeWMT-EEQFK-NV--QILgtyyswFHelFdrMFkdgkeM-------TWKALCDSDQPenpakvkgPe----GLss 471  spotted gar
XP_002590862 4676 D-----WVP-QDKFE-DLmaMSV------LPgpLdsLCk---hVaedT--DDWERWYMSLAPeee---rlPyrppteqee 4734 Florida lancelet
XP_017833357 4048 GvarpAWLG-PRAWR-ECemLEL-LP-P-FS--G--LCa---sLag--hsNAWQSYLSLSStvl---gpaPgpgpePL-- 4108 white-tufted-...
XP_011951949 3798 GvarpAWLG-LRTWH-ECemLEV-LP-P-FA--G--LCa---sLag--haSVWQAYLSLSSsvl---gpaPgpgahPL-- 3858 sheep
XP_016294321  835 dgeveaMLD-EEQLA-RV--QVFkrl-afFR--T--IEe---hMe--AntDKWLAFLNSNNPet----svPvfwsedeq- 895  Pseudozyma br...
4RH7_A       2812 S---------------LF-Q--QILVVQVLRPDRLQSAMALFACKT----LGLKE-VSPL-P---------LNLKRLY-- 2856
Q23DR0       3903 Psmsefd----ltvnnLL-R--DLTVIKIFRPDRFLVVAKRLVSKV----MGSKFlEDi--Q---------IDMKQVV-- 3958 Tetrahymena t...
A0D7F8       3873 Ddir---------------qldDLHILRIFRADRFQIIARKLINQI----LGEGFmDEq--T---------VDMKLVV-- 3920 Paramecium te...
XP_002604212 4492 Y----------------YtPmqRYCVIRALRSDRIMHASSHFVSKV----LGKKYaGEIP-----------LDLPGVL-- 4538 Florida lancelet
EKC41076     4655 K---------------DFaPmkRLLVVRAVRSDRLMQASTVFIHRV----LGKNIlQGPEqDytgyygdmgLDLSVMY-- 4713 Pacific oyster
XP_015211261  472 L---------------TAlQ--RLLVVRAIRSDRLIQAASLFIGST----LGKKYiTEIP-----------SDLQRCI-- 517  spotted gar
XP_002590862 4735 qgadtgpgspdmgpmtDF-H--QLLIIRCLRPDRLPFAMAKYVQKHmpgvLGNKT------T---------PNLETIL-- 4794 Florida lancelet
XP_017833357 4109 ----------------SLlQ--KLILWRVLRPECLADALADFTTSL----LGQ--------P---------LNANMGApt 4149 white-tufted-...
XP_011951949 3859 ----------------SLlQ--KLILWRVLRPECLVSTLATFTTSL----LGR--------P---------LDENLSAht 3899 sheep
XP_016294321  896 ---------qdedladQV-R--KMLVVKCLRPDRIVQAMAAFASRI----FGQDVlGDp--G---------YELGRIV-- 946  Pseudozyma br...
4RH7_A       2857 ---KE------TLEIEPILIIISPGAD---------------PSQELQEL-------AnAERs-gECYHQVAMGQG-QA- 2902
Q23DR0       3959 ---EKd----sN-CKSPILMCSAPGFD---------------PSYKVDAL-------A-KEMg--VRHISVAIGSQ-EGf 4004 Tetrahymena t...
A0D7F8       3921 ---EKe----aS-NKIPILLCSAPGFD---------------PSFKVEQL-------S-REMg--IKLTSVAIGSA-EGf 3966 Paramecium te...
XP_002604212 4539 ---RQ------STPQTPIILLYTAESDl--------------AETLFVEF-------A-VKKqepRQVVYLSSGSP-QEe 4586 Florida lancelet
EKC41076     4714 ---KQsapvppSTLSLPILLLYSFEAEa--------------AQSRFLDF-------S-GRRqapRLMVTITDNSQ-ATr 4767 Pacific oyster
XP_015211261  518 ---QQ------TTAQTPVLLLYSREAEe--------------PRRLVLEL-------C-SQRsckTEVVFVSEDSA-SEe 565  spotted gar
XP_002590862 4795 ----Dt----aGDSHIGVLVLLSPSLNsssqpniaaidikkhPVEVLKSL-------A-KG----IPVEHVAVGDG-CE- 4852 Florida lancelet
XP_017833357 4150 mpfKH------SQATQPILILLPPPGH---------------PTATLHPLtaiqklaA-KHQqgqKHLQVIALGSEtWD- 4206 white-tufted-...
XP_011951949 3900 ipfEH------TQATQPILILLPPPGH---------------PTATLHHLtviqklaA-RHQqgkKHLKVIALGSEtWD- 3956 sheep
XP_016294321  947 ---AEe----vD-ASTPVALCSVPGYD---------------ASYRVDHL-------V-KLVg--ARCTPVAMGSQ-EGf 992  Pseudozyma br...
4RH7_A       2903 DL--AIQMLKEC-ARNGDWLCLKNLHLVVS-W---LP-V-LEK------------------E----LnTLQPK-D----- 2945
Q23DR0       4005 DL--ADKAIQQA-AKSGIWVLLKNVHLAPS-W---LS-E-VEK------------------SihrlTph----------- 4046 Tetrahymena t...
A0D7F8       3967 DQ--AEQAITQS-VKSGSWVMLKNVHLATS-W---LN-D-LEK------------------KlfrlTpn----------- 4008 Paramecium te...
XP_002604212 4587 RR--VRRAITKA-AEEGHWLLLHNAHNALH-F---LQ-T-LDTtl---------------qEkklpAd------------ 4630 Florida lancelet
EKC41076     4768 SK--VRKTIRKA-IAEGSWVYLHNAHNAPN-V---LN-S-LESfl---------------vEkpnpE------------- 4810 Pacific oyster
XP_015211261  566 RR--IKDVIENG-QSKGSWVLLENIHNSMH-----LMtS-IESmi------------------------hLNKnPn---- 608  spotted gar
XP_002590862 4853 SR--VDVAIDTAhNNDG-WVIIEDIHLASPqF---LH-E-LKLhl--------------------------aRvShtatg 4898 Florida lancelet
XP_017833357 4207 PVsvVVSTVYQA-MCEGNWLVLDNCHLMPH-WpkeLL-QlLLEllgrarviadlkseqllgQpesrNvAT-Vh------- 4275 white-tufted-...
XP_011951949 3957 PVsiVISSLRKA-MLRGEWLVLENCHLMPH-WpkeLL-QpLLGlldgakevsdldlellfaQqanrNvAA-Vh------- 4025 sheep
XP_016294321  993 AL--ADHAITSA-ARTGNWVLLKNVHLAPS-W---LS-Q-LEK------------------KmhglNpn----------- 1034 Pseudozyma br...
4RH7_A       2946 ------------TFRLWL----TAEVHP------N-FTPI---------LLQSSLKITYE-------------------- 2973
Q23DR0       4047 -----------nNFRLFL----TMEFNP------K-VPST---------LIRQSYKLVFE-------------------- 4075 Tetrahymena t...
A0D7F8       4009 -----------aNFRIFL----TMEFNP------K-IPTT---------LIRQSYKLVFE-------------------- 4037 Paramecium te...
XP_002604212 4631 -----------sNFRLWV----SAQPHP------K-LPIH---------LLQHAIKVVVD-------------------- 4659 Florida lancelet
EKC41076     4811 ------------GFRLWV----ACQADP------EvIPVR---------LLQNSIKAVVD-------------------- 4839 Pacific oyster
XP_015211261  609 -----------kQFRLWI----SAQANT------S-IPVR---------LMHVSLRIVVD-------------------- 637  spotted gar
XP_002590862 4899 lkdrsaqdggrsSFQVWL----TSEPSA------T-IPED---------LLNSLHKVAWDvigphllggqeaqgpallah 4958 Florida lancelet
XP_017833357 4276 -----------rDFRLWLivpaEASASLpavltqHsMPVFwnqslelghVLIDSVELAQQgly----------------m 4328 white-tufted-...
XP_011951949 4026 -----------rDFRLWLtvsaEATASLpavltqHsMPVFwdqslelghVLVDSVELVQQgls----------------v 4078 sheep
XP_016294321 1035 -----------rNFRLFL----TCETSP------S-IPVN---------FLRASRILMNE-------------------- 1063 Pseudozyma br...
4RH7_A       2974 -SPPG-LKKNLMRTY-------E-----SWTPeqiskkdntHRAhALFSLAWFHAACQERRNYIPQ-GWTKFYE--F--- 3033
Q23DR0       4076 -PPSG-IKASLQRSFaslltpar-----------tdrlpreRSR-LHFLLAWLHAILLERLRYTPI-GYTKVYE--F--- 4135 Tetrahymena t...
A0D7F8       4038 -PPDG-IKASLIRTFktvlsqqr-----------tdrqpveRAR-LHFLLAWLHAVILERLRFTPI-GWSKTYE--F--- 4097 Paramecium te...
XP_002604212 4660 -TPMM-MRDHMVRSMqwiepetl-----------ktstrpeWPA-VLHNLFMVHGALRLRARFGRG-GWNRPGDmvF--- 4721 Florida lancelet
EKC41076     4840 -TPKV-MKDSMIRSFswfepdil-----------kqssrpeWPV-MLHNLCFLHAAIQLRARFGQG-GWNCPQD--Ffni 4902 Pacific oyster
XP_015211261  638 -TPKN-MKDAMLRCLqqvgpdal-----------rscsraeWPA-LIHNLCYLHCAVRLRAAAGGttGWNFRHAmmF--- 700  spotted gar
XP_002590862 4959 gSPQGmLKKAIGAALssvpaqsWdklrdKSNN---------IRN-MVFGLCVVQGVLLARQLYGTR-GLSLQYP--L--- 5022 Florida lancelet
XP_017833357 4329 qPL--------------------------------------TQA-LPLLL--LHGLLLHRQLYGV------RLQ--A--- 4356 white-tufted-...
XP_011951949 4079 qPP--------------------------------------SRV-LPLLL--LHGLLLHRQLYGM------KLQ--A--- 4106 sheep
XP_016294321 1064 -PPPG-IRASMLDSLksiapgr------------lqrgpaeTPR-LYFLLAFFHATLTERLRYTPL-GWSKPFE--F--- 1122 Pseudozyma br...
4RH7_A       3034 SLSDLR----AGYNIID-RLF-DGA----------KD--------------VQWEFVHGLLENAIYGGRIDNYFDLRVLQ 3083
Q23DR0       4136 NEADQR----CSLDLID-EFV--DSlgdrs-nidpDK--------------LPWEAIRTILCQNLYGGKIDNEYDGKILE 4193 Tetrahymena t...
A0D7F8       4098 NEADQR----CSLDLID-EYV--DAlgirq-nidpSK--------------LPWDAFRTILTQNLYGGKVDNEYDQKILQ 4155 Paramecium te...
XP_002604212 4722 GNNELQ----EGLRLVLdEFS--------------DTtstdmp--gtpgkgIAWTALRYMLTEVIYGSYVSDEYDQLTLS 4781 Florida lancelet
EKC41076     4903 GYSCLQ----EALAIVQnEFK--------------EPltsvapdgsqnsrsVSYNGIRYMVAEIVYGSHVTDFYDQQSLC 4964 Pacific oyster
XP_015211261  701 GIQEFR----DALQVLReEFR--------------DGstsdv----gegrsVSWTGIRYLLTNVIYGKNITDDCDKRSLA 758  spotted gar
XP_002590862 5023 SGVQLR----QGIDILVgKALnEGG----------EEp-------------TVDEACKAL-AEMVYGNIMGTDWDRQYTT 5074 Florida lancelet
XP_017833357 4357 HRGRWSqvtlTRVLQTQ------------------DQlwa--------slsNPSAAMQELTASVFYGGPLGDTEDREALI 4410 white-tufted-...
XP_011951949 4107 HRGHWSqatlTHVLQIQ------------------DQlca--------slsNPSVAMRELAASVFYGGPVGDDKDREVLI 4160 sheep
XP_016294321 1123 NDSDAE----AALDIIE-GWV--AQvakgranvdpQQ--------------LPWDAIRSLLKQSVYGGKIDNNPDQTLLD 1181 Pseudozyma br...
4RH7_A       3084 SYLKQFFN-----------SSVIdvfnqrnkksiFPY----Sv------sLPqs-cS----ILDY---RAVI-EKI-PE- 3131
Q23DR0       4194 SLVEHLFN-----------PNAFnanydmfst---------sekniqlikMPea-----irQSQY---VEWIe-KL-PN- 4242 Tetrahymena t...
A0D7F8       4156 SLVEQFFT-----------EQSFnhnhplfft----------legkeaitVPeg-----rtYLDF---MQWIe-QL-PK- 4203 Paramecium te...
XP_002604212 4782 AMVDYWMG-----------PNAMkke-----fevPRLkh----------kIPaaffAnyirYNSLvqaLEQIpNFF---- 4831 Florida lancelet
EKC41076     4965 AMVDFWLS-----------SGALkrd-----fevKGLky----------rHPqaffNpnvrLNTLiqaLDSApNHN---- 5014 Pacific oyster
XP_015211261  759 SLVDLWIS-----------STATkkd-----ndmTKLky----------rIPaaffDpdapLEGLlqaLDSVpRHT---- 808  spotted gar
XP_002590862 5075 TVLHE----------------IL-----------YLItnqsGrlmlgsvpIPt--pAanvdPSEY---ARWFeSCF-ESd 5121 Florida lancelet
XP_017833357 4411 SLIQACLSpsdrsrvqphtPQSL-----------LAMlm----------pLPak------eLDAMaecKAQM--HLlRS- 4460 white-tufted-...
XP_011951949 4161 SLTRACLSsssgngaqphtPQYL-----------LATlm----------pSPel-----keLDALeecKGQM--HLlPT- 4211 sheep
XP_016294321 1182 SFVDELFC-----------AQAYdvdfqlvk------------ddkdplvAPeg-----tkIETF---VSWVq-AL-PE- 1227 Pseudozyma br...
4RH7_A       3132 DDKPSFFGLPANIARSSQRMI---S--SQVISQLRIl-------------------------------G----RSitAGs 3171
Q23DR0       4243 VESPAWSGLPVNAEKILKEQN---T--ERALNLLWTl-----------------------------------qDVndEEi 4282 Tetrahymena t...
A0D7F8       4204 TESPEWSGLPSNVERVQRDQL---T--QKLITKVQNl-----------------------------------qQEgeEEi 4243 Paramecium te...
XP_002604212 4832 LDVPEACNMHSFTETLLGDDQyifTrlNSVYDIMPSsptlshvvsprpptpyagpplttisatsslplVvnrgVFatQTy 4911 Florida lancelet
EKC41076     5015 LDVPEGCHIHQTIVTLLGDDQyvfTrlNKVFDSMPStltlshkmfprpptpfdgpaqagisktsnnpsVvhqgVFstASy 5094 Pacific oyster
XP_015211261  809 LDVPEGTSLHSAPGLHFGDEQyacHwlKTLYKSLSFhhqqhsfavq---------------------------------- 854  spotted gar
XP_002590862 5122 HSATEALLLDESVDRDWNEASssvY--VAHLDQLLT-------------------------------------HTqcGPy 5162 Florida lancelet
XP_017833357 4461 PPEPRLCGLNEGPQAWLLRRQ---S--RALLSALQQs------------------------------sPmwvpAThgGA- 4504 white-tufted-...
XP_011951949 4212 PPEPRICGLSAGSQTWLLRRQ---S--RAILSALQRc------------------------------sPtwvpAArgTS- 4255 sheep
XP_016294321 1228 QQPPQWLALPPSAEKVIAAAQ---G--TALLSKLVRm-----------------------------------kQLadDDd 1267 Pseudozyma br...
4RH7_A       3172 ---------------------------------------KfDRE---------IwsneLSPV-LNLW-KKLNqn------ 3195
Q23DR0       4283 eeidmgv------------------------kpktggqgQqSQQvqw----lrT----VQER-SESFlKVLP-------- 4321 Tetrahymena t...
A0D7F8       4244 tqi---------------------------------ednKkSDQvqw----lqD----LLEK-VEKFkAILP-------- 4273 Paramecium te...
XP_002604212 4912 aa-----------------------------------lkNrKEQ---------E----LYEL-STTLlTKVPraw----- 4937 Florida lancelet
EKC41076     5095 at----------------------------------hkiRfKDV---------E----LWQI-CNDLlQKTPkignssks 5126 Pacific oyster
XP_015211261  855 ------------------------------rhcrdfllkSrKEE---------E----VWEI-CCNIqAKIPkgw----- 885  spotted gar
XP_002590862 5163 psksivskevsldvqrlrfaidlcvdglppllelgrlpaQvDSSsfsfqyhrpS----MVSV-ATVPpEEMPe------- 5230 Florida lancelet
XP_017833357 4505 ---------------------------------------QlADR---------R----LRQRxV-QAsRRLE-------- 4523 white-tufted-...
XP_011951949 4256 ---------------------------------------RrAER---------R----LRQR-LAQAkRRLE-------- 4274 sheep
XP_016294321 1268 detigqstggsss------------saaketasstaassSsSVQpsw----mkA----LRAN-AMQWlDLLP-------- 1318 Pseudozyma br...
4RH7_A       3196 -sNL-----------------------IHQkvpppndrqgsPILS----------------FIILEQFNAIRLVQSVHQS 3235
Q23DR0       4322 ------------------------------------------QQIeklnrtatsmndplfrFLEREITVGTKLLNEIKSN 4359 Tetrahymena t...
A0D7F8       4274 ------------------------------------------NKIsplertadsindplfrFLDREITVASKLLKAVRQN 4311 Paramecium te...
XP_002604212 4938 gkEYiadrikk-------------------------lggataFNV----------------FIQREVEALMKLIGEVRRS 4976 Florida lancelet
EKC41076     5127 frEFvvekirk------------------------lpgdypiFND----------------FIMKECEILHQLLTEVRNT 5166 Pacific oyster
XP_015211261  886 skDFinerlkk-------------------------iggntpFNL----------------FLKKELNHLMELLSEVKRN 924  spotted gar
XP_002590862 5231 -----------------------------------------SLGF----------------ILLQECHWLNLLLCHVRQS 5253 Florida lancelet
XP_017833357 4524 --SLqdllihpvrqnesgapwsvlgpnARR-----------PLEG----------------VLETEALELSQLVGTLQRD 4574 white-tufted-...
XP_011951949 4275 --SLqaqlteimrqeesgvgfgelglsAPL-----------PLEG----------------FLKTEVLELSQLVGALQRD 4325 sheep
XP_016294321 1319 ------------------------------------------STVssfgkdagsvqdplyrFWAREHRTGSSLLSTVRKD 1356 Pseudozyma br...
4RH7_A       3236 LAALSKVIR-GTTL--LSSEV---QKLA-SALLNQKCPLAWQSKwE-GP-ED-PL-----QYLRGLVARALAIQN--WVD 3298
Q23DR0       4360 LKDVIQMAA-GNIA--GTNVT---KQLA-KDVYSDVVPKAWVKf-N-S--YCtSLn----EWIFDFKQRIDQFNKlaiip 4424 Tetrahymena t...
A0D7F8       4312 IEELIQLAQ-GKIL--ATNIL---RQLA-KDVFNNIVPAQWNKy-N-V--ITmPLn----DWVGDFKRRIDQFDLlgktk 4376 Paramecium te...
XP_002604212 4977 LNAIKAASD-TVEAlpLGDQLsedYLTVaDDLYHYRTPELWCRL---GGdAVpPPtwnpaQWLTDLTNRHAHFEK--LLS 5050 Florida lancelet
EKC41076     5167 LTTIRNACE-NNV---MGDQLsdhYLSAaDDLYHLRIPRIWCKM---TGtTApPYtynaaQWLRDLEDRWKHFEK--ILS 5237 Pacific oyster
XP_015211261  925 LQAIRQSME-GPLR--VGGTLsvtELSVaADLFRQRVPTHWSSL---EGqDTpPEhwataTWVRDLQQRVLHFEKilQLg 998  spotted gar
XP_002590862 5254 LHNLDQCMLgGTNA--IPASL---TQLA-EALQSEEVPVSWT-----HP-RCrPSshtilSWLADLQERYKQFHD--WVK 5319 Florida lancelet
XP_017833357 4575 LDCLLQQLK-GAPPc-PSRRC---AAVA-HALRTGRLPSPWR---PhAPaGSqPPw----HWLRQLSRRGQLLVR--YLG 4639 white-tufted-...
XP_011951949 4326 LDCLLQQLK-GAPPc-AARRC---AAVA-QALWTGRLPAPWR---PhAPaGPqPPw----HWLRQLSRRGQLLLR--YLG 4390 sheep
XP_016294321 1357 LLEVVAVCD-GNSR--QTNHN---RALL-TDLPKAVIPQSWRRy-A-VP-KAmTLp----EWIVDLRARLEQLERitrea 1422 Pseudozyma br...
4RH7_A       3299 -Ka-------eKqallsET-----------LDLSELFHPDTFLNALR-----------------------QE-TAR-AVG 3334
Q23DR0       4425 n------------------------yqksgVWIGQLLYPEAYMTATR-----------------------QF-VAQ-NNA 4455 Tetrahymena t...
A0D7F8       4377 d------------------------fqkgqVWFGGLLFPEAYLTATR-----------------------QY-VAQ-ANK 4407 Paramecium te...
XP_002604212 5051 qgr-----ekfP-----A------------YWPGAFFQPRALFGLLKse-------------------svKN-FTD-KY- 5086 Florida lancelet
EKC41076     5238 mgr-----kamP-----A------------YWLGAFFNPRGLLALLKqe-------------------aiKN-YCGdRS- 5274 Pacific oyster
XP_015211261  999 qe-------kmP-----T------------YWLGAFKNPKGLLGVFRqq-------------------siQQ-HAE-QT- 1032 spotted gar
XP_002590862 5320 hGivsk-epdrP-----TSqpqlshgqltsVWLGGLVNPAALFTALR-----------------------QE-KAV-QLE 5368 Florida lancelet
XP_017833357 4640 -VgadagsdvpE-----HV-----------FHLSAFRHPRRLLLALQreaaldqnvpssnlagsrgsfssQLpYKR---- 4698 white-tufted-...
XP_011951949 4391 -Vgtq----vpE-----RI-----------FHLSAFCHPRRLLLSLRweatfavvapt-nfpacqtssscQLpHKR---- 4444 sheep
XP_016294321 1423 ------aevggA-----SGggyd----mveVILGLLFSPGAYLTATR-----------------------QS-VAH-ASK 1462 Pseudozyma br...
4RH7_A       3335 RSVDSLKFVASWKGRLQEAKl--QiK----ISGLLLEGCSFDG--NQLSEnQLDSPSVSSVLPCFMGW--IPQDacgPYs 3404
Q23DR0       4456 WSLEELELQASVYS----EGdqlgd-dcflVKGMSIEGA--DWkgTQ--L-LLSNEIRIMLPPIIFKW--AR-----SSt 4518 Tetrahymena t...
A0D7F8       4408 WSLEELELQ--MIP----EDqgide-dsfvIEGVSMEGGHLDSktLQ--V-RIVNEISVALKPITLKW--CK-----TSq 4470 Paramecium te...
XP_002604212 5087 GYVEPLMFQTEITARDKDHLrdppn-egmfVFGLYLWGCTWEKttSELLD-TPPKSGPSTLPVIHVTCvpqsdklt---- 5160 Florida lancelet
EKC41076     5275 GNFEQFTFQTDTTFRDFGHLlqpPpeg-vyIHGIHLWGCSIEKttNEFQD-QASRQGYAPLPVLHLQCypVNEK---PAl 5349 Pacific oyster
XP_015211261 1033 GFIEPMDLHTVITQRDKDHIrdpP-QegvfVYGLHVWGVSWHKteAEILD-APPKHGPVALPVIHLRFlpksekagl--- 1107 spotted gar
XP_002590862 5369 VPVSKITLSCEVVRDDTAVVeeeg---glyIQGLYIQGAAWDWqaGCLTE-AEMGL--TPLPAVYVKP--VLTS---Eap 5437 Florida lancelet
XP_017833357 4699 LEMNSNLLHLRVENGPNPTVper----gllLIGLQVLHAEWDPttGALQD-SPSSQ-PNPLPPVSISTqapgtsdq---- 4768 white-tufted-...
XP_011951949 4445 QELISP-LHFQVANSPHPTVpem----gllLIGLQLHNAKWDPvaGALQD-SSSSQ-PSPLPPVSVSAqapaandl---- 4513 sheep
XP_016294321 1463 VSLENLSLKLLLND----PKaglda-gkfaIRGLKLQGANWDAesKK--I-RLNDGAVTNLGLTALVWd-KQ-A---DSq 1529 Pseudozyma br...
4RH7_A       3405 --------PdecISLPVYTSAERDR-------VVTN-------IDV----PCGg--NQDQWIQCGAALF 3445
Q23DR0       4519 kgv--qdgQ---IMVPVYLNKARKNli--------------fsLKM----NCGhipR-AQLYQKAITLI 4563 Tetrahymena thermophila ...
A0D7F8       4471 kgv-vgddE---IVLPVYLNKTRKNli--------------fsLKV----KMGklnR-YTLYQKGLSFI 4516 Paramecium tetraurelia
XP_002604212 5161 ----dpvkaaetYQCPCYI-------------SRTNckepvltLDV----RHDg-iTATRWSLRGLAGT 5207 Florida lancelet
EKC41076     5350 q-----epS---FQCPLYA-------------SRIAprdpimeIDI----KKEg-iPPMRWALRGLTAT 5392 Pacific oyster
XP_015211261 1108 ---gdaaraadpYQCPVYG-------------SSAGprgpvlhLQV----YKEn-iPAARWALRGMKAT 1155 spotted gar
XP_002590862 5438 gpgrdggeditlYDCPVFMNKARQvc----------------sLTLplrcPSP----TENFIMSGAAVI 5486 Florida lancelet
XP_017833357 4769 ----pppegltvYSCPVYM----AGplgttklQSRNiv---mhLPL----PTKl--sPSTCVQRRVHVC 4820 white-tufted-ear marmoset
XP_011951949 4514 ----pprgglavYSCPVYL----EGplgttrlHRRKvl---mhLPL----PTKl--sPATCIQRRVHVC 4565 sheep
XP_016294321 1530 kdq-aqqgK---VLISVYLNQDRSQal--------------faTLL----DVDagvKAATVAQRAVALR 1576 Pseudozyma brasiliensis ...
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