2JGZ


Conserved Protein Domain Family
Cyclin_C

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pfam02984: Cyclin_C 
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Cyclin, C-terminal domain
Cyclins regulate cyclin dependent kinases (CDKs). Human CCNO is a Uracil-DNA glycosylase that is related to other cyclins. Cyclins contain two domains of similar all-alpha fold, of which this family corresponds with the C-terminal domain.
Statistics
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PSSM-Id: 335178
View PSSM: pfam02984
Aligned: 240 rows
Threshold Bit Score: 36.059
Threshold Setting Gi: 147636834
Created: 22-Mar-2017
Updated: 23-May-2017
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
2JGZ_B 134 PLPLHF----LRRA--SKI---------------GE-V--D----VEQHT--LAKY----------LMELTM-LDYD--M 170 human
Q9ZRX9 198 YTPYTF----IDYF--MRK------------------MngDqipsRPLI---SGSM----------QLILSIiRSID--F 238 common tobacco
Q8LGA1 180 ITPCSYiryfLRKMskCDQ------------------EpsN-----TLIS--RSLQ----------VIASTT-KGID--F 221 thale cress
Q4KYM5 212 VTPFSYidyfLRK---LNS---------------GNaAprS--------W--LLRS-----------SELILrIAAGtgF 252 Japanese rice
Q9ZR04 156 VTPFSF----LAFF--ISL---------------FElKeeDp--lLLKHS--LKSQ----------TSDLTFsLQHDisF 200 thale cress
O15995 255 ITVNTW----LNAF--MQIcnaeeianrktnfhfPS-YssT-----EFV---QVAQ----------LLDVCT-LDIG--S 306 Hemicentrotus pulcher...
P24864 244 LTIVSW----LNVY--MQV------------------AylN-----DLHevlLPQYpqqifiqiaeLLDLCV-LDVD--C 291 human
P47794 246 LTPVAW----LNIY--MQM---------------AYlKetA-----EVL---TAQYpqatfvqiaeLLDLCI-LDVR--S 293 zebrafish
Q5ZMH4 247 VTIISW----LNLY--LQV---------------DAlKdvP-----KVL---LPQYsqekfiqiaqLLDLCI-LDVN--S 294 chicken
Q9Z238 241 VTVISW----LNLF--LQV---------------DAvKdvP-----KVL---LPQYsqetfiqiaqLLDLCI-LAID--S 288 house mouse
2JGZ_B 171 VHFPPSQIAAGA--FCLALKIL---DNGEWTPTLQHYL-SY---TEESLLPVMQHLAKNV------VMVNQGltKH-MTV 234 human
Q9ZRX9 239 LEFRSSEIAASV--AMSVSGEI---QAKDIDKAMPCFFiHL---DKGRVQKCVELIQDLTt-----ATITTA--AA-ASL 302 common tobacco
Q8LGA1 222 LEFRPSEVAAAV--ALSVSGEL---QRVHFDNSSFSPL--FsllQKERVKKIGEMIESDGsdlcsqTPNGVL--EV-SAC 291 thale cress
Q4KYM5 253 LEFRPSEIAAAVaaTVAGEAT----GVVE-EDIAEAFT-HV---DKGRVLQCQEAIQDHH--------YSMA--TI-NTV 312 Japanese rice
Q9ZR04 201 LEFKPSVIAGAA--LLFASFELcplQFPCFSNRINQCT-YV---NKDELMECYKAIQERDiivgenEGSTET--AV-NVL 271 thale cress
O15995 307 MDFDYSILAASA--LYHVTNE----------EVTLSVT-GL---KWDDIAACVQWMSTFAm----tIREVGV--AQlKNF 364 Hemicentrotus pulcher...
P24864 292 LEFPYGILAASA--LYHFSSS----------ELMQKVS-GY---QWCDIENCVKWMVPFAm----vIRETGS--SK-LKH 348 human
P47794 294 LEFSYSLLAASA--LFHFSSL----------ELVIKVS-GL---KWCDLEECVRWMVPFAm----sIREAGS--SA-LKT 350 zebrafish
Q5ZMH4 295 LDFQYRTLAAAA--LCHYTST----------EVVKKAS-GL---DWDNISECVEWMVPFVn----vARKVS---VK-LKH 350 chicken
Q9Z238 289 LEFQYRILAAAA--LCHFTSI----------EVVKKAS-GL---EWDDISECVDWMVPFVs----vVKSVSP--VK-LKT 345 house mouse
2JGZ_B 235 KNKYATSKHAKISTLPQL 252 human
Q9ZRX9 303 VPQSP---IGVLEAAACL 317 common tobacco
Q8LGA1 292 CFSFKTHDssssythls- 308 thale cress
Q4KYM5 313 QPKPASTRRGSASASSSS 330 Japanese rice
Q9ZR04 272 DQQFSSCESDK-SITITA 288 thale cress
O15995 365 KNIYAGDAHNI-QTHCSS 381 Hemicentrotus pulcherrimus
P24864 349 FRGVADEDAHNIQTHRDS 366 human
P47794 351 FKGIAADDMHNIQTHVPY 368 zebrafish
Q5ZMH4 351 FKKVAVEDCHNIQTHTNY 368 chicken
Q9Z238 346 FKKIPMEDRHNIQTHTNY 363 house mouse
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