Conserved Protein Domain Family
EcKinase

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pfam02958: EcKinase 
Ecdysteroid kinase
This family includes ecdysteroid 22-kinase, an enzyme responsible for the phosphorylation of ecdysteroids (insect growth and moulting hormones) at C-22, to form physiologically inactive ecdysteroid 22-phosphates.
Statistics
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Aligned: 51 rows
Threshold Bit Score: 233.7
Threshold Setting Gi: 74870324
Created: 20-May-2020
Updated: 7-Aug-2020
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
Q9VPY7        39 GLDGFMSALYTVTLDV---------VIAERKRT----EVVLVKFMKGTEEFRESSNSYIQFSNEIFAYAEILPAYENVLR 105 fruit fly
XP_003436049  63 EGDNYMSIIKRVKAHCkak----svDGRNHVFT----ISLIFKRQITNPNRRRLFRCDAAFENEITAYASIVPVLQRISP 134 Anopheles gambi...
Q9VSS3        64 SGDNYMSVVKRVTISQagkdqdpelAGSEI-------VTVIVKRQIASLSRRQLYRCEEAFSNEINAYRHLAPLLAAHSR 136 fruit fly
Q7PQT3         1 RGDNYTAALFRIALKGhtl---pdgGTKKLKWE----KSIICKRLPDCKIKREAFKSEALFRNEVVFYNTIMPEYVAFQR 73  Anopheles gambi...
Q9VEB7        55 RGDNYTAALYRIKLTG---------KRRSLKWE----QNVICKVMPESVVAREAYKSDKLFRNEVQFYNTIMPELLKFQA 121 fruit fly
Q7QBD5        43 KGDAYLSELYRIQLTG---------EPAEPGRDeplvVNVVVKTIPKNVGRRNTFRSADFFRNEANFYNVVLKELYRFQ- 112 Anopheles gambi...
Q9W3C3        42 KGDAYLSRVFRITIYGvke---aeeGQDEKQLE----ISVIVKAMPDNLHRRRLFRSVIFFRNEINFYTKVLPAIEAFQK 114 fruit fly
Q9VYW8        52 KGDNYLGVVWRLQ--------------AASDSK----RSLVVKLPPQNRVRRKQFFARPCFLRETAAYEVFLPLTALIQD 113 fruit fly
Q9VW98        33 VGENAYGQVLRVSWPTiv-----------------daATVVVKMAPRNEARRSHMHVVDYYAREVFMYQKVFPVFRALSP 95  fruit fly
XP_321568     75 KGDGFIGELFRAYL-------------TEGDRR----EAYLCKIPPLNEARRQQFETMEIFEREVLMYNKLLPLMFAYQE 137 Anopheles gambi...
Q9VPY7       106 TShles---------evvkNWVPCCYFARfg-hvEGLGngrESVLALKHLKGDGYQLGPR-LTLRRDQLEAMVGLVGPFH 174 fruit fly
XP_003436049 135 YD-----------------LPYPKCVTAG-----SDEH---GDRIVLEDLTTSGYAMLDRrVGLSYEHCIAVMKELAKLH 189 Anopheles gambi...
Q9VSS3       137 HQ------------------LFPVCHIAEsqdrrDAEGg--EPIIVLQDLKAMGFRMKDRlAGLELSDCLLVMKKLAQLH 196 fruit fly
Q7PQT3        74 RQvetvgagtdvpaserlfQAIPHCYLAR------------DDLIVLEDLRVRSFTMPDRqAGLGPQQLEAVLAELARFH 141 Anopheles gambi...
Q9VEB7       122 SKtnqd---------tpvfNAIPKCYSAR------------HDLLIMEDLRERGFQMSDRhKGLSLEETQSVLLQVAQLH 180 fruit fly
Q7QBD5       113 DArkpa----------npfKDINPCYVAY-----TDGV---NDFVAMEDLGQYGYKTASRaEGVGLEECKRCMRSLGRFH 174 Anopheles gambi...
Q9W3C3       115 SRqpap---------kkpfVEYPRCLASL-----CDGV---NDFIALEDVGPRGYRAPVRqDYISLEDALLTMRTLGRFH 177 fruit fly
Q9VYW8       114 KWkiig---------ddrfRQHALCFGTR-----QDEP---NECIVLEDLSCAGFSLHNRfLDLSVEHVRRVMLTYAKLH 176 fruit fly
Q9VW98        96 DRnt--------------fTVAPALQAND-----LKAP---DEFLIFEDLSESGFRPNSRcIMPTYDIVVCSLKALAELH 153 fruit fly
XP_321568    138 AKgvsr---------edgfFSIPKCYHAH-----YDGQs-aEAIIVMEDLRLNHYSMFNKdKPVDYEHARLTMEQLGRYH 202 Anopheles gambi...
Q9VPY7       175 ALGYATKILQPNVHARLR--AGVVDMPFVSSSGKGIFDVLYRVAFDRFYEFYDRQKEQLLQGAdpgfgAAIERLRE--KY 250 fruit fly
XP_003436049 190 AVSLAMKHAHPHEYADVC--SKIREIVYCPEA-AEFYTHSLESSLRGALDSLRYSNGEQGELDgp--iRAVEGLTG--RL 262 Anopheles gambi...
Q9VSS3       197 AASLAAQELESSSFAFHA--DHLQEIVYCDEA-TDFYATILDTSVQQALESLGDANADDCLTTp---iRLLEELRT--NL 268 fruit fly
Q7PQT3       142 AVSLAYQRrHPAEFRQLT---GALEEGIFSQANEEWYRRYYDVLTRNAIQMVRQTVPEKRDHL-----AKLERFLG--NC 211 Anopheles gambi...
Q9VEB7       181 GLSLAYKFEKPLEFSNLC---SMISEGIFCTANTSWYRNYYERLTKNAIQMVSEVLPPDSKYV-----LAMNKFAEssSF 252 fruit fly
Q7QBD5       175 ALSLAMKEQEPDRFHEIA--QQHVEETYYSARLKSWYNNFLQVQIDIARDAMAREYPGTELER------TMEKFFDc-DL 245 Anopheles gambi...
Q9W3C3       178 GVALAFNALDSKNFEKAA---GSLEETYYGEHTREWYTGFLLLAENVATDAVKQIYPNSKYET-----VATNFLQP--PL 247 fruit fly
Q9VYW8       177 AISLAGKRQLPEKMQQLQqlVDIFEQRRDDHALGVYFENLKESALSALLAPADDAYRVR---------LEAYFARG--SY 245 fruit fly
Q9VW98       154 ACSFILQQTDPLQFKQLV--EFVEKDNLFTSDIEEVTIEFGKAQLRKARIILKES----DGDQvaavqEVLQLCEN--QL 225 fruit fly
XP_321568    203 AVSLAMKHDRPEQFEQFK----MLDSMKESMSPEHPFIVMLQKTTRDAMETL---EPHEARER-----NKMQKLLN--GM 268 Anopheles gambi...
Q9VPY7       251 FKQPTLLLerirtssfaedQPDSHFATFLHGDYNRNNVLFHYGAED--KVDAIKAIDFQELRFSTTAIDLSFFMYMNTPS 328 fruit fly
XP_003436049 263 YRIMSALVc---------dGMDEGWRVICHGDTWVNNLMFSADRQH------VRLIDLQTMRCTTPVLDILHLLYTSTEH 327 Anopheles gambi...
Q9VSS3       269 FENLKHEIn---------aTAAAPNSVICHGDLWVNNIMFRS------EPEEVIFFDLQAMRKSSPIFDILHFIYTSTRR 333 fruit fly
Q7PQT3       212 FGHLVELV-----------NRTSELSVICHGDCWTNNILFRYDEAG--AIAETCLVDFQLIRHGSLALDLAYLIYCCTDG 278 Anopheles gambi...
Q9VEB7       253 FGRMVKLA-----------STESPLSAICHGDCWVNNFLYHYDPEDphRVLEVALLDFQLIRYSSIALDIANLLYCCTTK 321 fruit fly
Q7QBD5       246 YDHMVYLT-----------HTRNQNSVINHGDCWMPNFLF-HDSTP-----AMRMIDFQLARYCSPALDIAFFVYSCTSQ 308 Anopheles gambi...
Q9W3C3       248 FDDLINLV-----------STRSKLSVFGHGDCWTPNFLTKYNERG--QSEEIIIIDFQLARCSSLALDLSFFIYSCTSQ 314 fruit fly
Q9VYW8       246 FELLLPLVs---------gFNCEPFAVICHGDCWNNNILYKSTERG--ELEDVRLIDWQLMRYASPVTDLAYFLFTCTSR 314 fruit fly
Q9VW98       226 KSLALYCVd---------gKAQAPHAVICHGDFWNNNILYRHEPNSd-QPVEAKLIDFQMSRYAPPVLDIVHYLFACTEK 295 fruit fly
XP_321568    269 LADVDRYAn---------fELAEPYAVLGHGDCWINNMMYRYK-NG--TPEHIVLLDWQVARYCSPILDLAYFIFCCTDE 336 Anopheles gambi...
Q9VPY7       329 EGRKEIYADLLRKYHRSMIEmLELVLRR 356 fruit fly
XP_003436049 328 SMRRQYVPELLLQYRQSL----LAALGE 351 Anopheles gambiae str. PEST
Q9VSS3       334 PLRDVHTDTLLAAYSQALSE-ELRHQLE 360 fruit fly
Q7PQT3       279 ALRKKSLQHWLQTYHQQLVR-SLRLLLG 305 Anopheles gambiae str. PEST
Q9VEB7       322 EMRDAQLQTLLKIYTEELFR-WLQMLCT 348 fruit fly
Q7QBD5       309 ALRDAHYEDLLGAYHGGLAE-MLRDLGS 335 Anopheles gambiae str. PEST
Q9W3C3       315 ELREQHYDELLRAYLESAQD-LIQDLGG 341 fruit fly
Q9VYW8       315 RFRQRHLENMLEDYYEELGL-QLIRLGE 341 fruit fly
Q9VW98       296 RLRDEHFPDFMDAYYNTMDQ-KLKSCNL 322 fruit fly
XP_321568    337 EFRRRHYDEMMSIYYNSLAT-LLEKLGH 363 Anopheles gambiae str. PEST
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