1LW3


Conserved Protein Domain Family
GRAM

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pfam02893: GRAM 
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GRAM domain
The GRAM domain is found in in glucosyltransferases, myotubularins and other putative membrane-associated proteins. Note the alignment is lacking the last two beta strands and alpha helix.
Statistics
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PSSM-Id: 308507
View PSSM: pfam02893
Aligned: 30 rows
Threshold Bit Score: 64.6669
Threshold Setting Gi: 75024739
Created: 16-Jul-2016
Updated: 4-Aug-2016
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
1LW3_A   81 LLP-GENIKDmakdvTYICPF--T---------------GAVRGTLTVTNYRLYFKSMERDPPf---vLDA--SLGVI-- 135  human
Q9VU19   32 SGQ-DNPIFK-----------------------------GSKGGRIYLTSHRMIFNSKKSSDSmq--sFSA--PFVALs- 76   fruit fly
P97765   32 FND-MKNVPE-----AFK---------------------GTKKGTVYLTPYRVIFLSKGKDAMq---sFMM--PFYLMk- 78   house mouse
Q18966   35 TSE-NENLE------------------------------GRRTGTIYLTSHRIIFMPDPGDWLk---sFEI--PFNSMq- 77   Caenorhabditis elegans
Q9TXP3  794 LAH-GEFLISd----PIDCYLltSieesems-lnrlenlLPADGSLFLTNYRVIFKGKSVDINatngtIVQtiPLYSM-- 865  Caenorhabditis elegans
Q9VGH9  929 LLP-GEDLVTd----HLRCFLmpDgrede------tqclIPAEGALFLTNYRVIFKGSPCDPLfceqvIVRtfPIASLlk 997  fruit fly
Q9Y751  594 LPD-SEELLA-----SYFCHFqkN---------------IPVYGKVYLGTTCICYRSLFPGTNt---tMIL--PYSDI-- 645  Komagataella phaffi...
Q06321  578 FNK-EKSLIS-----TYYTYLnrN---------------VPVYGKIYVSNDTVCFRSLLPGSNt---yMVL--PLVDV-- 629  Saccharomyces cerev...
Q6IC98  453 LTE-NERPLAvcengWRCCLInrDrkm---------ptdYIRNGVLYVTENYLCFESSKSGSSkr--nKVI--KLVDI-- 516  human
O95248  889 LLPgEECVLD-----GLRVYLlpDgreegaggsaggpalLPAEGAVFLTTYRVIFTGMPTDPLvgeqvVVRsfPVAALtk 963  human
1LW3_A  136 -NRVEK--IGGASSRGENSYGLETVCKDi-rNLRFAHKPEGRTRRSIfeNLMKYAFP 188  human
Q9VU19   77 dVEIEQ--PVFGANYIKGKVRAQPNGNYv-gEVKFKLHFKAGGAIEYgqALLRSAKT 130  fruit fly
P97765   79 dCEIKQ--PVFGANFIKGIVKAEAGGGWe-gSASYKLTFTAGGAIEFgqRMLQVASQ 132  house mouse
Q18966   78 dVNLNQ--PIFGANYLCGIASAVQGGQMr-gEVKWRMTFNRGGCIEFgqSLLQAVER 131  Caenorhabditis elegans
Q9TXP3  866 -ESFKK--LTNKKLIPTQLIEKGVKIEH---IISIRSSCASSIIIAFdeDEINNMAI 916  Caenorhabditis elegans
Q9VGH9  998 eKKISVlyLAHLDQTLTEGLQLRSSSFQl-iKVAFDPEVTPEQIESFrkILSKARHP 1053 fruit fly
Q9Y751  646 -ENVYN--LKGFRFGYSGLVIVIRAHEEl--FFEFGSNESRDDCDLFllKQLDFTKS 697  Komagataella phaffii GS115
Q06321  630 -ETCYK--EKGFRFGYFVLVIVIHGHEEl--FFEFSTEVARDDIERIllKLLDNIYA 681  Saccharomyces cerevisiae S288c
Q6IC98  517 -TDIQK--YKVLSVLPGSGMGIAVSTPStqkPLVFGAMVHRDEAFETilSQYIKITS 570  human
O95248  964 eKRISV--QTPVDQLLQDGLQLRSCTFQl-lKMAFDEEVGSDSAELFrkQLHKLRYP 1017 human
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