5GAN_B 1846 TLSNGLIASHYGVSFFTIQSFVSSLSNTS-TLKNMLYVLSTAVEFESVPLRKGDRALLVKLS-KR------LPLRFpeh- 1916 baker's yeast O60072 1618 PTTLGRIVSYYYLFHTTIRNFVQKITENA-EFDLALQLLAEASEFDDLAIRHNEDLINIEIN-KS------LKYSAacl- 1688 Schizosacchar... Q6BM64 479 CTEYGDVMTKYYILYPTMRNIIRSKAGN--TLLDVLTIFSRSSEFSEFSIKYNEKKLYKAINlSPyi---rFPLHSt--- 550 Debaryomyces ... Q5D892 534 PEEPGRLMTKYYLKFETMKYIINT--PTSySLDEALHIVCHAEEISWIQLRRNEKKTLNDVNaDK----------Egrlr 601 thale cress Q16RG8 556 ATLYGRLMAQYCLNFRTVKLLRK-IKGTE-PLLEIFTLLTYCDEFAVFKCRNSDKRTLNELNrSStrstirFPLRg---- 629 yellow fever ... A2PYH4 777 PTEAGRLMAWYYITFETVKKFYT-ISGKE-TLSDLVTLIAGCKEFLDIQLRINEKKTLNTLNkDPnritirFPMEg---- 850 human A2RUV5 646 PTETGKLMALYYIAFNTAKLFHT-IRGTE-TLAELVSLISSCSEFSDVQLRANERRVLNTLNkDKnrvtirYPMEg---- 719 tropical claw... XP_001704428 2044 PTPLGEIVSRYYIRTRSGALINTWLTGEThTLQSYLDMLVRCEEFQEIPIRHNEDRDSALLL-QK------YLWDGk--- 2113 Giardia lambl... CBI34887 532 PLEPGRLMTKYYLKFGTMKHIMQT--PLNcSLEDALHIICRSEEIAWIQLRRNEKKFLNDINmDK----------Dgqlr 599 wine grape EEE57380 447 PLEPGRLMTKFYLKFDTMKLIVKA--SACcTLEDLLHIICHSAEITWIQLRRNEKKLLNEINaDK----------Egrlw 514 Japanese rice
5GAN_B 1917 ---------tssG-----------------SVSFKVFLLLQAYF-SRLELP---------VDFQNDLKDILEKVVPLINV 1960 baker's yeast O60072 1689 ----------nlPm---------------vDAHVKAFILTQAHM-ARLKLPv--------DDYVTDTSTVLDQVIRIIQS 1734 Schizosacchar... Q6BM64 551 ------------Ef---------------qDSD-KVMLLLQYEL-CGLDFPnspelmklyYSFEGDKCYVFKQASRIIRC 601 Debaryomyces ... Q5D892 602 fhindnkgkrkkRi---------------qTREEKLFVLANDWLtGDPSVHd--------LSMTQDANSICSNGSRIARC 658 thale cress Q16RG8 630 ------------Ri---------------qSTTAMASCLMQAVF-GNLPIEd--------GSLQQEATKMINIGRRLIKC 673 yellow fever ... A2PYH4 851 ------------Ri---------------kTREMKVNCLIQAQL-GCIPIQd--------FALTQDTAKIFRHGSRITRW 894 human A2RUV5 720 ------------Ki---------------kTKEMKVNCLIQAHL-GCILVQd--------FSLTQDISKIFRHGTRLAKC 763 tropical claw... XP_001704428 2114 -----------rEfsgalirynmpdditctEPSFKAHILLQAQL-VRSSLQgafe--lpvVDYWLDLVTIIDAAIRITVA 2179 Giardia lambl... CBI34887 600 fhilgdkgkrkrRi---------------qTREEKIFVLANDCLtGNPSVHd--------LSLTQDANAICSNGCRIAKC 656 wine grape EEE57380 515 fhvvgangkrkkRi---------------qTREEKIFILANDCLtGDPLVHd--------LSLNQEMNSICSNGCRVAKC 571 Japanese rice
5GAN_B 1961 VVDILSANGY---------LNa--TTAMDLAQMLIQGVW-DVDNPLRQIPHFNNKIL------EKCKEINVETV------ 2016 baker's yeast O60072 1735 YIDVSAELGY---------SHv-cLQYISLMQCLKQACY-PSEIYRASLPGLNASSE------KEARDYLNKFA------ 1791 Schizosacchar... Q6BM64 602 MIDVFRYKKD---------CVs-lLNTLRFSRCVAGRCWeNSVTELKQLDGIDEECI------KKLRKNNISGF------ 659 Debaryomyces ... Q5D892 659 MKEYFIYKKN---------YKg-tLSSTLLAKSLYQKLWdDSPYLLKQLPGIGMVTA------KALHSMGVRSF------ 716 thale cress Q16RG8 674 MTEFIYVGQGtigqdgggvYQa-lLSTVVLSQCLETKLWeNSPYITKQLKGIGAIYA------GQLAARGKISF------ 740 yellow fever ... A2PYH4 895 LSDFVAAQEKk--------FAv-lLNSLILAKCFRCKLWeNSLHVSKQLEKIGITLS------NAIVNAGLTSF------ 953 human A2RUV5 764 LSEFLALQENk--------FSa-fLNALILTKCFKSKLWeNSSHISKQLEKIGVTLA------NAMVNAGLTTF------ 822 tropical claw... XP_001704428 2180 TVEIALAKRL---------SRsivQTVVQLSQGLVQGLW-PNMEPMLSISSLRNALQsnkktfQKLSANGISTLqqlvde 2249 Giardia lambl... CBI34887 657 MKEYFIYKKS---------YKg-aLNSILLSKCLLQKLWdDSPYLLKQLPGIGMVTA------KALHSMGIVSF------ 714 wine grape EEE57380 572 MREYFIYKKN---------YKs-aISSMLLAKCLHQKLWeSSPFLLKQLPGIGIVTA------KALKTAGIDSF------ 629 Japanese rice
5GAN_B 2017 YdIMALEDEERDEILTLTDSQLAQVAAF--VN-Ny-PNVEL-TYSLnnsdSLISG-----VKQK-----ITIQLTrdvep 2081 baker's yeast O60072 1792 ----GNKTDELYQMLCNDPNVFDIESLV--NSlIsyPKMNI---------EVSQS-----SSDK-----LLLYLRrlnqp 1846 Schizosacchar... Q6BM64 660 AeAKYLSQLQLEYFLGIEPGTGKNIAQS--LQ-Sl-PKFKInATLA----SNKVR-----TDLEtleisLIVSIGidnme 726 Debaryomyces ... Q5D892 717 EaLAEADPRRIEIVTGRKYPFGNTIKES--LS-SlpPKVEIkVEEV----DCQKQ-----GISK-----LAVTLSrvsqp 779 thale cress Q16RG8 741 QeLLDTNPRELEVILKKNPPFGSDLIAF--VR-Tl-PVFSI---------DLVLK-----KDYF-----LEVTVNqkndc 797 yellow fever ... A2PYH4 954 KkIEETDARELELILNRHPPFGTQIKET--VM-Yl-PKYELkVEQI----TRYSD-----TTAE-----ILVTVIlrnfe 1015 human A2RUV5 823 KkIEDTNARELELIVNRHPPFGNQIKES--VA-Hl-PKYEIkFQQL----AKYRA-----TTAE-----VVLTVLltnfk 884 tropical claw... XP_001704428 2250 FhKLGRKQLTEFLGKHQLLSGIQRKELCeeLM-Ky-PNLII-RATI----TRINRpanipDKSKhtgkfVCVIISlkhvs 2322 Giardia lambl... CBI34887 715 EaLAEADPRRIEIVTGRKYPFGNHIKES--LS-SlpPKVELkIEEI----ECQRQ-----GKSK-----IVLILTrlsqs 777 wine grape EEE57380 630 EsLATADARKIESVTGRNYPFGDSIKSY--LP-SlgPKIDInIEDA----G-NRQ-----GKST-----IIVTLTrlsqa 691 Japanese rice
5GAN_B 2082 e--nlqvtsEKYPFDK-----LESWWLVLGEVSKKELYAIKK---VTLNKEtqq------yeLEFDT-P-TSgkhnLTIW 2143 baker's yeast O60072 1847 lnpdfyifaPLFPKPQ-----SEGFFVLIIDSETQELFAIRR---ASFAGRrnddsirlslrISMDI-PpTCrnrnVKVM 1917 Schizosacchar... Q6BM64 727 r---gnskiK-----------HNFINTIIG-LSTGELLDFRRiaiLELVEGni-------nsFRLTAnVtDRqq-kIHCH 783 Debaryomyces ... Q5D892 780 ----------------lqstkRHYADLIVGSEEENLIHFHEK------I-RmedfsspysvtVLLERpHqQTkv-tVKAD 835 thale cress Q16RG8 798 ----------------yskklAVKISILVGDSNNNVLFFKEN------LDAnpggscwyqesFKLSDaTvAT----ATGH 851 yellow fever ... A2PYH4 1016 ql-qtkrtaSD----------SHYVTLIIGDADNQVVYLHKI------TDSvllkagswakkIAVKRaLkSEd---LSIN 1075 human A2RUV5 885 ql-qkkrtaPD----------SHFVMLVIGDDDNQAIFKQKI------MDSslfktgswtrkIEIKRaSkSTn---VCLN 944 tropical claw... XP_001704428 2323 si-qaspfpQQFSSEVykkskPHTWFLVLSESETDTVIDYKR---LSGfar--------ersQEFIIpFvSS----LCIS 2386 Giardia lambl... CBI34887 778 ----------------fqsikRYYADMVVGLEEDNLILFHEK------ISRvdefsspysttILLSTp-qQGkl-tVKAD 833 wine grape EEE57380 692 ----------------vgsskQNYADMVVGSEEDNAILFHEK------Inpy-------svkLYVPCp-pNAra-tLKVD 740 Japanese rice
5GAN_B 2144 CVCDSYLDADKELSFE 2159 baker's yeast O60072 1918 VVCDGYPLIYEHKIVl 1933 Schizosaccharomyces pombe 972h- Q6BM64 784 ILSEDMVNIDARYVLS 799 Debaryomyces hansenii Q5D892 836 LIFEEYIGIDLHETLL 851 thale cress Q16RG8 852 VICSNWTGLDCSKSIV 867 yellow fever mosquito A2PYH4 1076 LISSEFVGLDIQQKLT 1091 human A2RUV5 945 LISSEYVGLDIQQSFN 960 tropical clawed frog XP_001704428 2387 ALSDCFLGMDKEITID 2402 Giardia lamblia ATCC 50803 CBI34887 834 LIFEEYIGIDLHQKLL 849 wine grape EEE57380 741 VIFEEYVGLDIHKKHV 756 Japanese rice
Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.",