4KS0,1VP8,1T57


Conserved Protein Domain Family
PK_C

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pfam02887: PK_C 
Pyruvate kinase, alpha/beta domain
As well as being found in pyruvate kinase this family is found as an isolated domain in some bacterial proteins.
Statistics
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PSSM-Id: 460738
Aligned: 599 rows
Threshold Bit Score: 30.526
Created: 21-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
4KS0_A         399 EAVCSSAVNSVYEVRAKALLVLSNSGRSARLASKYRPD--CPIICATT-------------------------RMRT--- 448 Trypanosoma c...
jgi:Thein_1666  14 EAALKIAFKAFKERGLKHIVIASTFGDTGLKAAELFAGkeANLVVVTHnvgfrepgk--------ieitqemrAKIEslg 85 
CCQ33631        10 EELLDRAKTYAEDQDVDAVCVASTSGETGAKAAERFGE---DLVVVGHsygfdeene--------qeldadhvEAIEaag 78 
WP_012744561    13 DAVLDLVFETAVKEGIRHVVLPSTRGKVATKALEMVPEd-IDLVIVTHsvgfrksgv--------defdpevrKLYEntr 83  Kosmotoga
jgi:Mpal_1128   18 EAVLAIVDERLKEGDIKNVVVASTSGATGVTFAQALGKk-TNLVIISTkpgsktpgv--------wefdpaneKKIKrlg 88 
jgi:Daud_2132   12 DATIRAAVARARELSISRIIVASHRGQTAEKLLESG----LEIVCVTHqvgfarpge--------demppemrAKLAaag 79 
Q3AD73          14 DLVLELAAKEAREQNIHNIVVATCSGATAFKLLKYLNPgqFNLVAVTHhvgfagpgv--------delspenrQKLLaeg 85  Carboxydother...
WP_012309106    21 ERVLLAAKSRCEERGIKKVVIASETGRSAVKALEIFRDtgVKLIVVTHypsktwgprgdipiglrrkeyaetlRKLEeng 100 Candidatus Ko...
BAI61262        18 NTTLKTVREWALKYNIKRVLVPSKSGQTAQKAYNLFKNtgIILTIVGTdpnif---------------sseilAQLRsng 82 
Q2LV38          23 EAVLEAVASRAEELSIGKVLVATCSGETALKAKKILKTs-IQLIAVSHvtgfakpdf--------qemtdqkrKELEtlg 93  Syntrophus ac...
4KS0_A         449 -------------CRQLT-ITRSVDAVFydaeRYgedenkekrVQLG----VDCAKK---------KGYVVPGD--LMVV 499 Trypanosoma c...
jgi:Thein_1666  86 akvytgtmvlrniGTAIReLQQ--YSQQdliaNT---------LRLfg-qgIKVCVEialm--acdAGLVPP-E--DVIT 148
CCQ33631        79 gdvfvgpmafsnvGSAIAeR-GGYSTHEvi-aDV---------LRLfg-qgTKVAVEsplm--acdAGLVDSGA--RVLS 142
WP_012744561    84 hkilttthlfrglEGYFYkKFGGVYPPQff-aAA---------LRLfg-egTKVAVEialm--aadAGLIPIDQ--WVIS 148 Kosmotoga
jgi:Mpal_1128   89 grvirhthalsglEKSFTeRFSGISHSEil-aES---------LKTLfspgTKVGVEigim--aldSGAITLEKtiVVGG 156
jgi:Daud_2132   80 vkllttthllagiDRALRfKFQGVYPSEiv-aDA---------LRMlg-qgVKVCAEiagm--acdAGLVPPGE--DVVC 144
Q3AD73          86 fkvlttthlfagiDRAFRfKFQGIYPAEiv-aQS---------LRLlg-qgVKVATEiaim--aldAGLIPYGE--DVIA 150 Carboxydother...
WP_012309106   101 vrivqgtrpfappSRCINwDY--PTPEAii-dKT---------LEVfg-agTKIAIEvvlm--atdAGEVEPGE--EVIS 163 Candidatus Ko...
BAI61262        83 tkv----vfykdvPYTYTqd----------mkTA---------YRRmg-egFKVAVElgiiaayleEGDIN-----DVIT 133
Q2LV38          94 vpvltaqhafgglGRAIRnKFGTYQIDEim-aFT---------LRVfg-qgTKVAIElalm--aadAGLVRTDE--DIIS 158 Syntrophus ac...
4KS0_A         500 VHADHKvkgyPNQTRII 516 Trypanosoma cruzi strain CL Brener
jgi:Thein_1666 149 VAGTARg---ADTVAII 162
CCQ33631       143 IAGTGSg---ADTALLV 156
WP_012744561   149 AGGTGKg---LDTAYIL 162 Kosmotoga
jgi:Mpal_1128  157 TGATGRg---ADTALVV 170
jgi:Daud_2132  145 IAGSGTg---ADTACVI 158
Q3AD73         151 IAGTGEg---ADTAVVI 164 Carboxydothermus hydrogenoformans Z-2901
WP_012309106   164 CAGTYKg---LDTALVV 177 Candidatus Korarchaeum cryptofilum
BAI61262       134 LGGTKKg---VDTALVI 147
Q2LV38         159 VGGTGSg---ADTALVI 172 Syntrophus aciditrophicus SB
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