2YW2,1GSO,2QK4,2XD4,2IP4


Conserved Protein Domain Family
GARS_N

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pfam02844: GARS_N 
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Phosphoribosylglycinamide synthetase, N domain
Phosphoribosylglycinamide synthetase catalyzes the second step in the de novo biosynthesis of purine. The reaction catalyzed by Phosphoribosylglycinamide synthetase is the ATP- dependent addition of 5-phosphoribosylamine to glycine to form 5'phosphoribosylglycinamide. This domain is related to the N-terminal domain of biotin carboxylase/carbamoyl phosphate synthetase (see pfam00289). This domain is structurally related to the PreATP-grasp domain.
Statistics
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PSSM-Id: 335123
View PSSM: pfam02844
Aligned: 1018 rows
Threshold Bit Score: 61.2062
Threshold Setting Gi: 530555862
Created: 20-Mar-2017
Updated: 23-May-2017
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
2YW2_A         2 KVLVVGNGGREHAIAWKVAQSPLVKELYVAKGNAGIweiakrv--disptdvEK------LAEFAKNEGVD--FTIVGPE 71  Aquifex aeolicu...
Q3Z884         2 KVLVIGNGAREHAIVWKLSQSPKVTKIYVAPGNAGTsliaenv--aisctniKG------LLAFAKDNSID--ITFVGPE 71  Dehalococcoides...
Q8D245         2 NILVVGNGGREHAISWKIAQSIFSKKIYVAPGNAGTeidyklknidissndiNK------LVKFAKEKKID--LTIVGPE 73  Wigglesworthia ...
WP_013379514   2 KVLVIGSGGREHVLTWKIAQSPKVDKIYCAPGNGGMakiaecv--dlsvediDG------CVKFAREKGID--LTVVGPE 71  Clostridiales
WP_014356025   2 KVLMIGSGGREHVLTWKIAQSPRVEKIYAAPGNGGMaalaecv--dlsvediPG------CLDFAKKHDID--LTVVGPE 71  Acetobacterium ...
WP_025435994   2 KVLVIGNGGREHAIVWTLSKSQRVDKIYCAPGNAGTaaiaenv--disadniDA------LLDFAKKNDIG--LTVVGPE 71  Eubacterium aci...
WP_012663283   2 KILVVGSGGREHALTWKISQSTMVDKIYCAPGNAGTtqyaenl--aikaddiEA------LGLFAKENGVD--LTVVGPE 71  Desulfobacteriu...
AFU59188       2 NVLIVGSGGREHAIGWKISQSRHVDKIYFAPGNGGtfenld-----ikqndiDK------LVSFAKKQRSKklLTIVGPE 70  Candidatus Nitr...
WP_012499322   2 KVLILGSGAREHALAWAIARHPSVQKIYVAPGNGGIhhlgei-----aenipfKaddidgLLKFAKENKIG--LTIVGPE 74  Chloroherpeton ...
WP_012505080   2 KVLVIGSGAREHALVRSISNSQRVGKVFAAPGNGGTaimggk-----vqnvalKatdieaLLAFVTSEDID--LTVVGPE 74  Prosthecochlori...
2YW2_A        72 APLVEGIVDEFekR--GLKIFGPNKEAAKLE 100 Aquifex aeolicus VF5
Q3Z884        72 APLAGGVVDVF--AsaGLRIFGPCREAAQLE 100 Dehalococcoides mccartyi 195
Q8D245        74 EPLSNGISDVF--SyyKLPIFGPKKFSAKLE 102 Wigglesworthia glossinidia endosymbiont of Glossina brevipalpis
WP_013379514  72 VPLVMGMTDAF--EkeGMRVFGPNAKCAEFE 100 Clostridiales
WP_014356025  72 VPLVMGMVDAF--EaeGLKVFGPNKQCAQFE 100 Acetobacterium woodii
WP_025435994  72 VPLVLGIVDLF--EseGQRIFGPNRQCAMLE 100 Eubacterium acidaminophilum
WP_012663283  72 VPLSMGIVDHF--EsmGLRAFGPNKKAAQLE 100 Desulfobacterium autotrophicum
AFU59188      71 EPLSLGIVDAF--EkeDLRIFGPTRQAAMLE 99  Candidatus Nitrososphaera gargensis Ga9.2
WP_012499322  75 QPLEKGIVNRFknH--GLKIFGPSQEAAQLE 103 Chloroherpeton thalassium
WP_012505080  75 QPLEMGIVDRFrsE--GLSIIGPDRYAAQLE 103 Prosthecochloris aestuarii
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