2YW2,1GSO,2QK4,2XD4


Conserved Protein Domain Family
GARS_N

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pfam02844: GARS_N 
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Phosphoribosylglycinamide synthetase, N domain
Phosphoribosylglycinamide synthetase catalyzes the second step in the de novo biosynthesis of purine. The reaction catalyzed by Phosphoribosylglycinamide synthetase is the ATP- dependent addition of 5-phosphoribosylamine to glycine to form 5'phosphoribosylglycinamide. This domain is related to the N-terminal domain of biotin carboxylase/carbamoyl phosphate synthetase (see pfam00289). This domain is structurally related to the PreATP-grasp domain.
Statistics
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Aligned: 1008 rows
Threshold Bit Score: 61.2078
Threshold Setting Gi: 530555862
Created: 4-Jun-2019
Updated: 18-Jul-2019
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
2YW2_A                    2 KVLVVGNGGREHAIAWKVAQSPLVKELYVAKGNAGIweiakrvdisptdvEKLAEFAKNEGVDFTIVGPEAPLVEGIVDE 81  Aqui...
jgi:UWK_03000             2 KVLVVGSGGREHALVWKIHQSTRVNKIFCAPGNAGIkrmaecvdisvtdvDALVAFAKEQEIDLTVIGPEMSLTVGVVDA 81  Desu...
ESQ12486                  2 NVLVIGSGGREHSLVWKIRQSKRVDKIFCAPGNAGIkelahcvdigatdvEALVRFATENDIDLSIVGPEASLVEGVVDA 81  uncu...
jgi:Despr_1808            2 KVLVIGSGGREHALVWKLKQSKTVKAVVCAPGNAGIkaiaecvdiaagdlAGLLDFAVKERIDLTIVGPEEPLAKGIVDL 81  Desu...
Q6AL58                    2 KVLVVGSGGREHALVWKIKQSQKVEEVFCAPGNAGIeelatcvnisatdiKGLLHFAQKEKIDLTVVGPESSLVAGIVDL 81  Desu...
EIM63949                  2 KILVVGSGGREHTLVWKIAQSPLVDKIYCAPGNAGTatqaenvninaediNALAAFAEQNQIDLTVVGPEGPLVAGIADI 81  Desu...
CCK79155                  2 KILVVGGGGREHTLVWKISKSPMVEKIYCAPGNAGTqtlaqsvpinaddiDALAAFALENEIDLTVVGPEGPLVKGIADV 81  Desu...
BryantPSU:Cabther_A0427   2 KVLVLGGGGRESAMVWKILQAARVEKVYCVPGNAGIarmaecldldlkkpdkLAAVAKDLGIHLTVCGPEQPLVMGVADA 81  Chlo...
jgi:Mmc1_3465            24 NVLVVGGGGREHALVWKITQSPLVGTVYCAPGNAGIaqlatcveisvddlRAMKQFAIEKKIELVVIGPEVPLVMGMADE 103 Magn...
jgi:TherJR_0831           2 KVLVVGGGGREHALVWKISQSPKVTKVYCAPGNAGMaqiaecvaisvediDGLLTFAQQEGIDMTVVGPEAPLTMGLADK 81  Ther...
2YW2_A                   82 FekR--GLKIFGPNKEAAKLE 100 Aquifex aeolicus VF5
jgi:UWK_03000            82 F--EkeGLRIFGPTRDAAILE 100 Desulfocapsa sulfexigens DSM 10523
ESQ12486                 82 F--EdaGLRIFGPRQNAAILE 100 uncultured Desulfofustis sp. PB-SRB1
jgi:Despr_1808           82 F--EenGLRIFGPNSKGAILE 100 Desulfobulbus propionicus DSM 2032
Q6AL58                   82 F--EenGLRIFGPSQAAAILE 100 Desulfotalea psychrophila
EIM63949                 82 F--QekGLAVFGPSGAAAQLE 100 Desulfobacter postgatei 2ac9
CCK79155                 82 F--QekGLNVFGPSKAAARLE 100 Desulfobacula toluolica Tol2
BryantPSU:Cabther_A0427  82 FtrL--GLRFVGPSRAAACLE 100 Chloracidobacterium thermophilum B
jgi:Mmc1_3465           104 M--QeaGMKVFGPNKAAAAIE 122 Magnetococcus marinus MC-1
jgi:TherJR_0831          82 F--RvaGLKVFGPSRQAAELE 100 Thermincola potens JR
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