5WJ1,4RJJ,3EYA,1OZG,2PAN,1UPB,4GPE,1POW,5B46,3IAE


Conserved Protein Domain Family
TPP_enzyme_C

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pfam02775: TPP_enzyme_C 
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Thiamine pyrophosphate enzyme, C-terminal TPP binding domain
Statistics
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Aligned: 333 rows
Threshold Bit Score: 43.7285
Threshold Setting Gi: 81504691
Created: 30-Apr-2019
Updated: 18-Jul-2019
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
5WJ1_A 399 GVGQHQMwaaqfynykkPRQWLSsgGLGAMGFGLPAAIGASV----AnpdA-IVVDIDGDGSFIMN-VQELATIRVENLP 472 thale cress
Q8R837 361 DIGCYTLga------apPLEAID--TCICMGASISGSHGFQKaiehSgr-kqKIFSVIGDSTFFHSgITGLIDIVYNKGN 431 Caldanaerobacter subt...
Q6LZB6 360 DIGCYTLgg------fePLNAID--TTICMGASIGMAHGFEMarg--kefAkKSVAVIGDSTFWHSgVTGLIDIVYNKGH 429 Methanococcus maripal...
Q97HL0 361 DIGCYSLga------llPLRSID--SCICMGASIGIAHGMEKarg--tefInRTVAILGDSTFIHSgITGLIDIVYNKGN 430 Clostridium acetobuty...
Q6ANT1 392 DIGCYTLgf------lpPLSAMD--ACVCMGASVPMAHGMAKalg--egsHdKVVSVIGDSTFIHSgITGLINTVYNNSA 461 Desulfotalea psychrop...
Q74CD5 360 DIGCYTLgf------mpPLNAMD--TCVCMGASISSASGIVRvls--deeKkKVVAVIGDSTFLHTgVNSLMEMAYNKAP 429 Geobacter sulfurreducens
Q97B81 382 DIGCYTLga------lpPFNEQD--SATNMGSSVGISNGVFRat------gqIPVSIIGDSTFFHSgLQGVANAVYNGTP 447 Thermoplasma volcanium
Q97WQ2 388 DIGCYTLgl------lpPFDAQD--SSTDMGSSIGIANGVYRat------gnIPIAVIGDSTFFHSgISALANAVYNQTP 453 Saccharolobus solfata...
Q974C0 376 DIGCYSLgi------lpPFQEQD--SLTNMGSSLGIANGVFRat------giIPVAIIGDSTFFHSgLSALANAVYNNLP 441 Sulfurisphaera tokodaii
Q703W1 425 DIGCYSLgv--------nLGEQD--VLTHMGSSLGLGMGIAQadr-----ekLVVATIGDSTFYHAaLPQLVDLKTKRVP 489 Thermoproteus tenax
5WJ1_A 473 VKVLLLNNQHLGMVMQWEDRFYKANRAHtflgdPAqedEIFPNMLLFAAACGIP-AARvtKK--ADLREAIQTML----D 545 thale cress
Q8R837 432 AVPIILDNRITAMTGHQHNPGTGKTLMG-----ED---APEIDIAKLSEAIGVKrVRVvnPFklKEIEDAVDEAM----N 499 Caldanaerobacter subt...
Q6LZB6 430 STVIILDNSITAMTGHQENPSTGKTLSG-----ER---TNQIDFEALGRSIGINrICVvdAYdlKALEETIKEEV----N 497 Methanococcus maripal...
Q97HL0 431 STVIILDNAVTAMTGYQSNPTTGYNIKN-----EA---TKKVELEKLCRAVGVErIKVvdPFnvDEVESVVKEEI----A 498 Clostridium acetobuty...
Q6ANT1 462 STLIILDNRITAMTGQQQNPATGYNIKG-----EA---ANALDLEALCRAVGVKhVYTvdPHdiIKTREVMKEAV----A 529 Desulfotalea psychrop...
Q74CD5 430 ATVVILDNRITAMTGRQDNPASGWTLMD-----DS---TNAVDLVQLCTALGIRhVRVvdPLdlDQTRAALQEEM----N 497 Geobacter sulfurreducens
Q97B81 448 EIIIVLDNRSTAMTGQQPSPST------------------HISIENVARAMGIDfVDTfdPFdvKEGSDAVQKAAeyvkE 509 Thermoplasma volcanium
Q97WQ2 454 MLVLVLDNRSTAMTGQQPSPSK------------------EIDIGEVAKGLGVKyVRYvdPFdvNSSIRELSNALkwvkD 515 Saccharolobus solfata...
Q974C0 442 VLVVVLDNRVTAMTGQNPSPSK------------------EIDIANVAKGLGVEyVREidPFnlKESTKIIADATnwvkQ 503 Sulfurisphaera tokodaii
Q703W1 490 LLLVVMDNEYTAMTGGQPSPSR------------------DAPAEIFAQALGIKyF-VvdPAdvKTSVEKIREAVsl-aK 549 Thermoproteus tenax
5WJ1_A 546 TPGPYLLDV 554 thale cress
Q8R837 500 TDDTMVIIA 508 Caldanaerobacter subterraneus subsp. tengcongensis
Q6LZB6 498 AEEPSLIIT 506 Methanococcus maripaludis
Q97HL0 499 ACEPSVIIA 507 Clostridium acetobutylicum
Q6ANT1 530 LDEPSVVIS 538 Desulfotalea psychrophila
Q74CD5 498 RPEPSVIIT 506 Geobacter sulfurreducens
Q97B81 510 NKKPALIVA 518 Thermoplasma volcanium
Q97WQ2 516 NKQPAVVIA 524 Saccharolobus solfataricus
Q974C0 504 NRKPALIVA 512 Sulfurisphaera tokodaii
Q703W1 550 SGEPAVVVS 558 Thermoproteus tenax
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