1FM0


Conserved Protein Domain Family
ThiS

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pfam02597: ThiS 
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ThiS family
ThiS (thiaminS) is a 66 aa protein involved in sulphur transfer. ThiS is coded in the thiCEFSGH operon in E. coli. This family of proteins have two conserved Glycines at the COOH terminus. Thiocarboxylate is formed at the last G in the activation process. Sulphur is transferred from ThiI to ThiS in a reaction catalyzed by IscS. MoaD, a protein involved sulphur transfer in molybdopterin synthesis, is about the same length and shows limited sequence similarity to ThiS. Both have the conserved GG at the COOH end.
Statistics
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PSSM-Id: 334994
View PSSM: pfam02597
Aligned: 146 rows
Threshold Bit Score: 28.8136
Threshold Setting Gi: 81760316
Created: 15-Mar-2017
Updated: 23-May-2017
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
1FM0_D        4 VLFFAQVRELVGtdatevaaDFPTVEALRQHMAAQSDrwalaledGKLLAAVNQTLVSF----DHPLTDGDEVAFFPPVT 79  Escherichia coli
Q7VIB7        5 ILLNGKDYEIDE---------QVTILSLIKKLNITH---------KAMAIAVNTQVVKKplweSYILQNGDEVEILDFVG 66  Helicobacter hep...
Q7MQQ8       13 VWINGEEREFLD---------ALTLLEMIESLGIME---------KVMAAAVNTQIIKQaewgAFIPKAGDRIELLQFVG 74  Wolinella succin...
Q7MRV7        3 LIINGENKSFEK--------EGLSVKELLVLESVKMP--------EMVSIQLNDEFLREpeyaTTSLKEGDTINFLYFMG 66  Wolinella succin...
Q8G5F5        1 MQVNGEQVTLET---------PVSVADYLEAHGFRA---------ERVAIELNGEIIPRdkraDAMLDDQCVMEIVQFVQ 62  Bifidobacterium ...
Q89FP3        3 VIINGEQREVA----------SVSVDALLSELDYEG---------THFAIALNYDVVPKsrwaETSLKAGDEIEIITPRQ 63  Bradyrhizobium j...
Q8KJ36        3 LIVNGEPLETA----------ATSLAALLAALDYEG---------DWLATAVNSDLVHKanraEFQLSDGDRIEILSPMQ 63  Mesorhizobium loti
Q9RYY0       28 MQVNGEPRPCVP---------GLTLHGLLRELDIRP---------ERVAIAVNDDFYPGgqapDRELEEADVVEIVRVIG 89  Deinococcus radi...
WP_010972407  3 LLVNGDELDLA----------AETLAGLLASLDYEG---------EWLATAVNGDLVHSeeraGYVLKAFDRVEILSPMQ 63  Agrobacterium tu...
WP_004691418  3 IVLNGEAHETA----------SVTLAALLNEIEFDE---------AVVATALNGEFIPAnareDTHISEGDRIEVLAPMQ 63  Brucella
1FM0_D       80 GG 81  Escherichia coli
Q7VIB7       67 GG 68  Helicobacter hepaticus
Q7MQQ8       75 GG 76  Wolinella succinogenes
Q7MRV7       67 GG 68  Wolinella succinogenes
Q8G5F5       63 GG 64  Bifidobacterium longum
Q89FP3       64 GG 65  Bradyrhizobium japonicum
Q8KJ36       64 GG 65  Mesorhizobium loti
Q9RYY0       90 GG 91  Deinococcus radiodurans
WP_010972407 64 GG 65  Agrobacterium tumefaciens complex
WP_004691418 64 GG 65  Brucella
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