3A27,2ZZN,3A25


Conserved Protein Domain Family
Met_10

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pfam02475: Met_10 
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Met-10+ like-protein
The methionine-10 mutant allele of N. crassa codes for a protein of unknown function. However, homologous proteins have been found in yeast, suggesting this protein may be involved in methionine biosynthesis, transport and/or utilisation.
Statistics
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Aligned: 12 rows
Threshold Bit Score: 242.241
Threshold Setting Gi: 731672
Created: 19-Mar-2019
Updated: 18-Jul-2019
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
3A27_A  26 IKYQKIGDVVIVKKELSEDE-IREIV-----KRT-KCKAILLYTTQI--TGEFRTPHVKILYG-KE-TETIHKEYGCLFK 94  Methanocaldococcus ja...
O29554  21 RSFEIIGDVVIIEIPDEIMH-HSRDIveailKRHkHVKTVLRKVGEV--DGVYRVARYEPIYG-EK-TETVVREHGCRFL 95  Archaeoglobus fulgidus
Q58293  95 LSYDVVGDLVILQISDEVDEkIRKEIgelayKLI-PCKGVFRRKSEV--KGEFRVRELEHLAG-ENrTLTIHKENGYRLW 170 Methanocaldococcus ja...
O28306  90 TNYKVIGDIVVVKLDERARE-YAKVIgealmQIN-PCKAVWCDYGR---YGMKRKPRMELIAG-EG-SVTEHRENGCRFR 162 Archaeoglobus fulgidus
O27268   4 MKWARIGDIIVLNREADDPEal--------lEME-GVRSVIRVEGI---HGPLRRPRVRVLAG-SG-TETVHKENGCLFR 69  Methanothermobacter t...
Q58952   3 IKYQKIGDVVIVKKELSEDE-IREIVkr------tKCKAILLYTTQI--TGEFRTPHVKILYG-KE-TETIHKEYGCLFK 71  Methanocaldococcus ja...
Q8U3G7  28 kRWVKIGDVLLLPLRPELEP-YKYKIakayaEVL-EVKTVLRKGHI---YGETRKPDYEILYG-SD-TITIHVENGIKYK 100 Pyrococcus furiosus
O27901  88 RSFDIIGDTVILEIPEELQD-YRFIIgeaalEFT-GRKAVYMKRSGV--KGVTRTRELELIAG-SAlSETIHQEYGSRIK 162 Methanothermobacter t...
F5HAU9 155 sGFNTAGHVAHMNLRERYIP-YKKVIaevilDKTtNIRTVINKVDNVgaESEFRTFQYEVLAG-PDdMQVQVTENACSFE 232 Neurospora crassa OR74A
P38793 176 TGFTITGHIAHLNLRTEFKP-FDSLIgqvilDKNnKIECVVDKVSSI--ATQFRTFPMKVIAGkSDsLVVEQKESNCTFK 252 Saccharomyces cerevis...
2ZZN_A  95 LSYDVVGDLVILQISDEVDEkIRKEIgelayKLI-PCKGVFRRKSEV--KGEFRVRELEHLAG-ENrTLTIHKENGYRLW 170 Methanocaldococcus ja...
3A25_A  51 kRWVRIGDVLLLPLRPELEP-YKHRIaevyaEVL-GVKTVLRKGH-I--HGETRKPDYELLYG-SD-TVTVHVENGIKYK 123 Pyrococcus horikoshii
3A27_A  95 LDVAKIMWSQGNIEERKRMAFI-SNENEVVVDMFAGIGYFTIPLAKysKPKLVYAIEKNPTAYHYLCENIKLNKLNNVI- 172 Methanocaldococcus ja...
O29554  96 VDPTKAYYSVKLSGERERIARL-VGEGERVLVMFAGVGPYPIVIAKlaRPREVVGVELNPHAVEYFRQNVRLNKVEGVVk 174 Archaeoglobus fulgidus
Q58293 171 VDIAKVYFSPRLGGERARIMKK-VSLNDVVVDMFAGVGPFSIACK---NAKKIYAIDINPHAIELLKKNIKLNKLEHKIi 246 Methanocaldococcus ja...
O28306 163 IDVAKVMFSLGNQAERMRIARL-VEDGEVVVDMFAGIGYFSIPIAVhsKARRIYSIEINPESYKLLLENIKLNDVGNIV- 240 Archaeoglobus fulgidus
O27268  70 IDLSRVMWSRGNINERARIPSL-VEEGETVVDMFAGIGYFSIPVAVhsDPGRVYSVELNPDSFELLKSNITLNRVEGIIe 148 Methanothermobacter t...
Q58952  72 LDVAKIMWSQGNIEERKRMAFI-SNENEVVVDMFAGIGYFTIPLAKysKPKLVYAIEKNPTAYHYLCENIKLNKLNNVI- 149 Methanocaldococcus ja...
Q8U3G7 101 LDVARIMFSPANVKERVRMAKV-AKPNELVVDMFAGIGHLSLPIAVygKAR-VIAIEKDPYTFKFLVENIHLNKVEDRMs 178 Pyrococcus furiosus
O27901 163 VDIKDVYFSPRLANERETVAAQ-VKDGEVVLDMFAGAGPFAIAVARhgRASRVYAVDINPAAVRYIEENARLNHAEDVIv 241 Methanothermobacter t...
F5HAU9 233 FDYSKVYWNSKLEAEHRRLINM-FEPGEVVCDVMAGIGPFAVPAGK--KGVFVWANDMNPESNKYMQVAINRNKVSQYVr 309 Neurospora crassa OR74A
P38793 253 FDFSKVYWNSRLHTEHERLVKQyFQPGQVVCDVFAGVGPFAVPAGK--KDVIVLANDLNPESYKYLKENIALNKVAKTVk 330 Saccharomyces cerevis...
2ZZN_A 171 VDIAKVYFSPRLGGERARIMKK-VSLNDVVVDMFAGVGPFSIACK---NAKKIYAIDINPHAIELLKKNIKLNKLEHKIi 246 Methanocaldococcus ja...
3A25_A 124 LDVAKIMFSPANVKERVRMAKV-AKPDELVVDMFAGIGHLSLPIAVygKAK-VIAIEKDPYTFKFLVENIHLNKVEDRMs 201 Pyrococcus horikoshii
3A27_A 173 PILADNRDVEL--KDVAD----------------------------------------------RVIMGYVHKTHKFLDK 204 Methanocaldococcus ja...
O29554 175 VIEGDVEEVVPqlSGQFD----------------------------------------------RVVMPAPYSAENFIHL 208 Archaeoglobus fulgidus
Q58293 247 PILSDVREV----DVKGN----------------------------------------------RVIMNLPKFAHKFIDK 276 Methanocaldococcus ja...
O28306 241 PILGDSQFVTP--EGVAD----------------------------------------------RVVMGHI-YCHDYLHT 271 Archaeoglobus fulgidus
O27268 149 PILGDCREVAP--ELDAD----------------------------------------------RVIMGYVGRTHHFLDA 180 Methanothermobacter t...
Q58952 150 PILADNRDVEL--KDVAD----------------------------------------------RVIMGYVHKTHKFLDK 181 Methanocaldococcus ja...
Q8U3G7 179 AYNMDNRDFPG--VDIAD----------------------------------------------RILMGYVVRTHEFIPK 210 Pyrococcus furiosus
O27901 242 AVEGDVREFLRdrECFAD----------------------------------------------HIIMNLPGSACEFLDD 275 Methanothermobacter t...
F5HAU9 310 PICEDGRTFI---HHAADsvleahkngehvliapkpps------rakkapkpepkrvdipptisHFVMNLPATAIEFLGC 380 Neurospora crassa OR74A
P38793 331 SFNMDGADFIRqsPQLLQqwiqdeeggkitiplplkkrhrsqqhndqqppqprtkeliipshisHYVMNLPDSAISFLGN 410 Saccharomyces cerevis...
2ZZN_A 247 PILSDVREV----DVKGN----------------------------------------------RVIMNLPKFAHKFIDK 276 Methanocaldococcus ja...
3A25_A 202 AYNMDNRDFPG--ENIAD----------------------------------------------RILMGYVVRTHEFIPK 233 Pyrococcus horikoshii
3A27_A 205 ---TFEFLKDR------------GVIHY 217 Methanocaldococcus jannaschii
O29554 209 ---LRGKVRRG------------GFVHY 221 Archaeoglobus fulgidus
Q58293 277 ---ALDIVEEG------------GVIHY 289 Methanocaldococcus jannaschii DSM 2661
O28306 272 ---AIRALKER------------GVVHY 284 Archaeoglobus fulgidus
O27268 181 ---AMECVRDG------------GVIHY 193 Methanothermobacter thermautotrophicus str. Delta H
Q58952 182 ---TFEFLKDR------------GVIHY 194 Methanocaldococcus jannaschii DSM 2661
Q8U3G7 211 ---ALSIAKDE------------AIIHY 223 Pyrococcus furiosus
O27901 276 ---AIRALRDG------------GVIHY 288 Methanothermobacter thermautotrophicus str. Delta H
F5HAU9 381 yrgVYAGHEDLfsaesgrklplvHVHCF 408 Neurospora crassa OR74A
P38793 411 frgIFAAHTKGatdti--qmpwvHVHCF 436 Saccharomyces cerevisiae S288C
2ZZN_A 277 ---ALDIVEEG------------GVIHY 289 Methanocaldococcus jannaschii DSM 2661
3A25_A 234 ---ALSIAKDG------------AIIHY 246 Pyrococcus horikoshii
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