Conserved Protein Domain Family
Glucan_synthase

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pfam02364: Glucan_synthase 
1,3-beta-glucan synthase component
This family consists of various 1,3-beta-glucan synthase components including Gls1, Gls2 and Gls3 from yeast. 1,3-beta-glucan synthase EC:2.4.1.34 also known as callose synthase catalyzes the formation of a beta-1,3-glucan polymer that is a major component of the fungal cell wall. The reaction catalyzed is:- UDP-glucose + {(1,3)-beta-D-glucosyl}(N) <=> UDP + {(1,3)-beta-D-glucosyl}(N+1).
Statistics
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PSSM-Id: 426739
Aligned: 63 rows
Threshold Bit Score: 953.547
Created: 21-Mar-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
XP_011271950  839 FFPPKSEAARRISFFAQSVSTPIPEPTLVQSMPIFTVLIPHYGEKIILSLKEIIREDNANsrITLMEYLKQLYPTEWDCF 918 
XP_002966392  855 rVPHNLEARRRISFFSNSLFMTMPRAPQVEKMLSFSVLTPYYSESVLYTKNELLDENEEG--VSILFYLQKIFPDEWINF 932 
XP_003569838  888 nVPKNPEARRRITFFSNSLFMNMPRAPPVEKMVAFSVLTPYYNEDVLYSKDQLRRENEDG--ISILFYLQKIYEDDWANF 965 
Q9ZT82        876 SVPVNLEARRRIAFFSNSLFMNMPHAPQVEKMMAFSVLTPYYSEEVVYSKEQLRNETEDG--ISTLYYLQTIYADEWKNF 953  thale cress
KRH22386      848 nIPVNLEARRRISFFTNSLFMNMPHAPQVEKMMAFSVLTPYYSEEVVYSKEQLRVGNEDG--ISTLYYLQTIYDDEWKNF 925 
XP_002317308  879 dVPKNIEARRRIAFFSNSVFMNMPHAPNVEKMMAFSVLTPYYEEDVCFGKQDIRTPNEDG--ISIIFYLQKIYEDEWNNF 956 
Q9S9U0        870 NVPKNIEARERLAFFSNSLFMTMPQAPSVEKMMAFSVLTPYYDEEVMYRQEMLRAENEDG--ISTLFYLQRIYEDEWVNF 947  thale cress
XP_004232875  877 nVPKNKEARRRIAFFSNSLFMNMPRAPQVEKMMAFSVLTPYYDEEVLFGKESLRSPNEDG--VSTIFYLQKIYNDEWENF 954 
KRH10874      899 NVPLNLEARRRIAFFTNSLFMNIPRAPYVEKMMAFSVLTPYYDEEVLYSKEALRKENEDG--ITTLFYLQKIYEDEWKNF 976 
ERN06585      903 nIPRNLEARRRIAFFSNSLFMNMPRAPQVERMLAFSVLTPYYDEDVIYNKEQLHIENEDG--ISILFYLQRIFPDEWLNF 980 
XP_011271950  919 VKDTKLLATNNGSLpdtyvkydltnrwkndlggpldyrvdedeededpktktdtneeiveidgveddesdeiddemdgiq 998 
XP_002966392  933 LERMSSLGIK-ESD------------------------------------------------------------------ 945 
XP_003569838  966 LERMRREGMVNDDG------------------------------------------------------------------ 979 
Q9ZT82        954 KERMHREGIKTDSE------------------------------------------------------------------ 967  thale cress
KRH22386      926 MERMKREGMNNERD------------------------------------------------------------------ 939 
XP_002317308  957 MERMRREGTENENE------------------------------------------------------------------ 970 
Q9S9U0        948 LERMRREGAENEND------------------------------------------------------------------ 961  thale cress
XP_004232875  955 MERMRTEGMKDERE------------------------------------------------------------------ 968 
KRH10874      977 MERMHREGLKDEEA------------------------------------------------------------------ 990 
ERN06585      981 LERMRREGMKDQGE------------------------------------------------------------------ 994 
XP_011271950  999 dprvkrkgirfrrskavpttpeddilqgrindlpfycigFKTSSPefILRTRIWASLRTQTLYRTASGFTNYVRALKLLY 1078
XP_002966392  946 ---------------------------------------LWTADK--GLELRLWASYRGQTLARTVRGMMYYNRALQIQA 984 
XP_003569838  980 ---------------------------------------IWA-GK--FQELRLWASYRGQTLARTVRGMMYYYSALKMLA 1017
Q9ZT82        968 ---------------------------------------LWT-TK--LRDLRLWASYRGQTLARTVRGMMYYYRALKMLA 1005 thale cress
KRH22386      940 ---------------------------------------IWT-DK--LSDLRSWASYRGQTLSRTVRGMMYYYKALKLLA 977 
XP_002317308  971 ---------------------------------------IWE-KR--SRDLRLWASHRGQTLSRTVRGMMYYYRALKTLS 1008
Q9S9U0        962 ---------------------------------------IWS-KK--VRDLRLWASYRGQTLSRTVRGMMYYYSALKKLA 999  thale cress
XP_004232875  969 ---------------------------------------IWN-TK--AREIRLWASYRGQTLSRTVRGMMYYYKALKMLS 1006
KRH10874      991 ---------------------------------------IWT-EK--ARDLRLWVSHRGQTLSRTVRGMMYYYRGLKMLA 1028
ERN06585      995 ---------------------------------------LWG-ER--VRDLRLWASYRGQTLARTVRGMMYYYKALEMLT 1032
XP_011271950 1079 RVETPD-------LVQYYGPDQVG-------------------LEQDL---EAMA------------QRKYKLVIAMQRY 1117
XP_002966392  985 FLDSASend-lhgYREMLSRASSMaddsr----------ngshVHRDSfghGQSGslykeeqyraasSLKFTYVVACQIY 1053
XP_003569838 1018 FLDKASeiditegTKHLATFGSIRhendvyprnngfqqrpqrrLNRGA---STVSqlfkge-edgaaLMKYTYVVTCQIY 1093
Q9ZT82       1006 FLDSASemdiregAQELGSVRNLQgelggqsdg-fvsendrssLSRAS---SSVStlykgh-eygtaLMKFTYVVACQIY 1080 thale cress
KRH22386      978 FLDSASeietqegARELVPLNQENsngsnle-----rspspmtLSKAS---SSASllfkgh-eygtaLMKFTYVIACQIY 1048
XP_002317308 1009 YLDSASemdirmgTQELASHHSLRnnrgldgln-sikppsapkLTKAS---SNVSllfkgh-eygsaLMKFTYVVACQLY 1083
Q9S9U0       1000 FLDSASemdirmgTQIAPEARRSYytndggdnt--lqptpsqeISRMA---SGIThllkgs-eygsaMMKFTYVVACQVY 1073 thale cress
XP_004232875 1007 FLDSASevdirhgSQRIVSLGSSNqnnhlnrdg-pamlqtsrkLHRSS---SSVTllfkgh-efgaaLMKFTYVVTCQVY 1081
KRH10874     1029 FLDSASemdvrqgSEH----GSTNqnsslnglpsngpsslqtnLRPTG---SSVSmlfkgh-eygsaLMKFSYVVACQIY 1100
ERN06585     1033 FLDSASemslrdgLRDLVSAASSMpreeeess----savplrrLSRES---SSVSslfkgh-eygtaLMKFTYVVACQIY 1104
XP_011271950 1118 ARFTKEEKDDTE---FLLRAYPDIKISYLLE-EIdeshPQRHKTFYSCMIDGfsdkD-ENGDRIPRYKVKLSGNPILGDG 1192
XP_002966392 1054 GNQKAKNEHQAEeilFLMQKFEALRIAYVDEvP-----GRDAKTFYSVLVKY----DpASNQEVEIYRIQLPGPLKLGEG 1124
XP_003569838 1094 GNQKMAKDQRAEdilTLMKKNVALRVAYVDEvRH----EMGDMQYYSVLVKF----DqDLQKEVEIYRIRLPGPLKLGEG 1165
Q9ZT82       1081 GSQKAKKEPQAEeilYLMKQNEALRIAYVDEvPA----GRGETDYYSVLVKY----DhQLEKEVEIFRVKLPGPVKLGEG 1152 thale cress
KRH22386     1049 GAQKERKDPHADeilYLMKNNEALRVAYVDEvPT----GRDAKEYYSVLVKF----DqQLDKEVEIYRVKLPGPIKLGEG 1120
XP_002317308 1084 GQQKAKPDHRAEeilYLMKNNEALRVAYVDEvNL----GRDGVEYYSVLVKY----DqQLQREVEIYRIRLPGSIKIGEG 1155
Q9S9U0       1074 GQHKARGDHRAEeilFLMKNHDALRIAYVDEvDL----GRGEVEYYSVLVKF----DqQLQREVEIYRIRLPGPLKLGEG 1145 thale cress
XP_004232875 1082 GSQKTKRDPRAEeilNLMKDNEALRIAYVDEvNL----GRNEVEYFSVLVKY----DqQLKQEVEIYRIKLPGPLKLGEG 1153
KRH10874     1101 GRHKADKNPRADeilYLMQHNEALRVAYVDEvSL----GREGTEYYSVLVKY----DqQLQSEVEIYRIRLPGPLKLGEG 1172
ERN06585     1105 GAQKARKEARAEdilYLMKNHEALRVAYVDEvLA----GRDEVEYYSVLVKY----DrQLQREVEIYRVRLPGPVKIGEG 1176
XP_011271950 1193 KSDNQNHSIIFYRGEYIQVVDANQDNYLEECIKIRSVLAEFEEMDiDNTPPyvpgilykndldpvAIVGAREYIFSENIG 1272
XP_002966392 1125 KPENQNHALIFTRGEAVQTIDMNQDNYFEEALKMRNLLQEFTRYY-GMRKP--------------TILGVREHVFTGSVS 1189
XP_003569838 1166 KPENQNHAIIFTRGDAVQTIDMNQDNYFEEALKMRNLLEQYNYYH-GSQKP--------------TLLGVREHVFTGSVS 1230
Q9ZT82       1153 KPENQNHAMIFTRGDAVQTIDMNQDSYFEEALKMRNLLQEYNHYH-GIRKP--------------TILGVREHIFTGSVS 1217 thale cress
KRH22386     1121 KPENQNHAIIFTRGDAVQTIDMNQDNYFEEALKMRNLLEEYRHNY-GLRKP--------------TILGVRENIFTGSVS 1185
XP_002317308 1156 KPENQNHAIIFTRGDALQTIDMNQDNYFEEALKMRNLLEEFKAFY-GIRRP--------------TILGVRENIFTGSVS 1220
Q9S9U0       1146 KPENQNHALIFTRGDAIQTIDMNQDNHFEEALKMRNLLESFKTYY-GIRKP--------------TILGVREKVFTGSVS 1210 thale cress
XP_004232875 1154 KPENQNHAIIFTRGDAVQTIDMNQDNYFEEALKMRNLLEEFKENY-GLRKP--------------TILGVRENIFTGSVS 1218
KRH10874     1173 KPENQNHAIIFTRGDAVQTIDMNQDNYFEEALKMRNLLEEFNMSY-GIKKP--------------TILGVRENIFTGSVS 1237
ERN06585     1177 KPENQNHALIFTRGDAVQTIDMNQDNYFEEALKMRNLLQEYTKNY-GIRKP--------------TILGVREHVFTGSVS 1241
XP_011271950 1273 VLGDIAAGKEQTFGTLFARTLAE-IGGKLHYGHPDFLNGIFMTTRGGISKAQKGLHLNEDIYAGMNALIRGGRIKHSDYY 1351
XP_002966392 1190 SLAHFMSSQETSFVTLGQRVLANpLKVRMHYGHPDVFDRLWFISRGGISKASRVINISEDIFAGFNCTLRGGNVTHHEYI 1269
XP_003569838 1231 SLAWFMSAQETSFVTLGQRVLANpLKVRMHYGHPDVFDRLWFLTRGGLSKASRVINISEDIFAGFNCTLRGGNVSHHEYI 1310
Q9ZT82       1218 SLAWFMSAQETSFVTLGQRVLANpLKVRMHYGHPDVFDRFWFLSRGGISKASRVINISEDIFAGFNCTLRGGNVTHHEYI 1297 thale cress
KRH22386     1186 SLAWFMSAQETSFVTLGQRVLANpLKVRMHYGHPDVFDRFWFITRGGISKASRVINISEDIFAGFNCTLRGGNVTHHEYI 1265
XP_002317308 1221 SLAWFMSAQETSFVTLGQRVLANpLKVRMHYGHPDVFDRFWFLPRGGISKASKVINISEDIFAGFNCTLRGGNVTHHEYI 1300
Q9S9U0       1211 SLAWFMSAQETSFVTLGQRVLANpLKVRMHYGHPDVFDRFWFVPRGGISKASRVINISEDIFAGFNCTLRGGNVTHHEYI 1290 thale cress
XP_004232875 1219 SLAWFMSAQETSFVTLGQRVLADpLKVRMHYGHPDVFDRFWFLSRGGISKASKVINISEDIFAGFNCTLRGGNVTHHEYI 1298
KRH10874     1238 SLAWFMSAQETSFVTLGQRVLANpLKVRMHYGHPDVFDRFWFLGRGGVSKASRVINISEDIFAGFNCTLRGGNVTHHEYI 1317
ERN06585     1242 SLAWFMSAQETSFVTLGQRVLANpLKVRMHYGHPDVFDRLWFLSRGGISKASKVINISEDIFAGFNCTLRGGNVTHHEYI 1321
XP_011271950 1352 QCGKGRDLGFGSILNFTTKIGAGMGEQILSREYYYLGTQLPIDRFLSFYYAHAGFHVNNLFIVLSVQLFMI--VLVNLGA 1429
XP_002966392 1270 QVGKGRDVGLNQIALFEAKVASGNGEQTLSRDVYRLGHRLDFFRMLSFYYTTVGFYLNNMMVVLTVYAFLWgrVYLALSG 1349
XP_003569838 1311 QVGKGRDVGLNQISMFEAKVSSGNGEQTLSRDIYRLGHRVDFFRMLSVFYTTIGFYFNTMLVVLTVYTFAWgrLYLALSG 1390
Q9ZT82       1298 QVGKGRDVGLNQISMFEAKVASGNGEQVLSRDVYRLGHRLDFFRMLSFFYTTVGFFFNTMMVILTVYAFLWgrVYLALSG 1377 thale cress
KRH22386     1266 QVGKGRDVGLNQISMFEAKVASGNGEQVLSRDVYRLGHRLDFFRMLSFFYTTVGFFFNTMMVVLTVYSFLWgrLLLALSG 1345
XP_002317308 1301 QVGKGRDVGLNQISMFEAKVASGNGEQVLSRDVYRLGHRLDFFRMLSFYFSTVGFYFNTMMVVLTVYTFLWgrLYLALSG 1380
Q9S9U0       1291 QVGKGRDVGLNQISMFEAKVASGNGEQALSRDVYRLGHRLDFFRMLSFFYTTVGYYFNTMLIVFTVYAFLWgrLYLALSG 1370 thale cress
XP_004232875 1299 QVGKGRDVGLNQIAMFEAKVASGNGEQVLSRDVYRLGHRLDFFRMLSFFYTTVGFFFNNMIVVVMVYTFLWgrLYLALSS 1378
KRH10874     1318 QVGKGRDVGLNQISMFEAKIASGNGEQVLSRDVYRLGHRLDFFRMLSVFYTTIGFYFNSMVIVLMVYAFLWgrLYMALSG 1397
ERN06585     1322 QVGKGRDVGLNQISMFEAKVASGNGEQVLSRDIYRLGHRLDFFRMLSFYYTTVGFFFNTMMVVLTVYAFLWgrLYMALSG 1401
XP_011271950 1430 LAhES--TICEYDKDIPFTdlqvplgcynLQPVLDWVTIFVLSVFIVffiafVPLLVQELTERGAWRAVSRFFHHLASLS 1507
XP_002966392 1350 VE-----RGLLSSSTSNSA----------LTAALNQQFIVQLGLFTA-----LPMIVENSIERGFSKAVWDFFTIQLQLA 1409
XP_003569838 1391 LEa---gIQGSANVTNNKA----------LGAVLNQQFVIQLGFFTA-----LPMILENSLERGFLPAVWEFFTMQMNFS 1452
Q9ZT82       1378 VEk----SALADSTDTNAA----------LGVILNQQFIIQLGLFTA-----LPMIVEWSLEEGFLLAIWNFIRMQIQLS 1438 thale cress
KRH22386     1346 IE-----AAMESNSNNNKA----------LSIILNQQFMVQIGLFTA-----LPMIVENSLEQGFLQAVWDFLTMQLQLS 1405
XP_002317308 1381 VE-----KYALKHSSNNKA----------LGTILNQQFIIQLGLFTA-----LPMIVENTLEHGFLPALWDFLTMQLQLA 1440
Q9S9U0       1371 VE-----KIAKDRSSSNEA----------LGAILNQQFIIQLGLFTA-----LPMILENSLERGFLPAVWDFITMQLQLA 1430 thale cress
XP_004232875 1379 VE-----DYASKNATSNKA----------LGSILNQQFVIQLGVFTA-----LPMIVENSLEHGFLPAVWDFITMQLQLA 1438
KRH10874     1398 IE-HGikHAAMNNATNNKA----------LGAVLNQQFAIQVGIFTA-----LPMVVENSLEHGFLPAVWDFLTMQLQLA 1461
ERN06585     1402 IEa---aIMVDADSTNNTA----------LGTVLNQQFIIQLGLFTA-----LPMIIENSLEHGFLQAIWDFITMQLQLA 1463
XP_011271950 1508 PFFEVFVCQIYATSLIVDITFGGARYISTGRGFAVSRIHFSYLYSKFASSSIYSGTKLFLML--------LFATVSIWQP 1579
XP_002966392 1410 SMFFTFSMGTKTHYFGRTLLHGGAKYRATGRGFVVKHERFAENYRLYSRSHFIKGLELALLLvvyeaygsFSKDTVVYIL 1489
XP_003569838 1453 SVFYTFSMGTKSHYYGRTILHGGAKYRATGRGFVVQHKSFAENYRLYARSHFIKAIELGIILtvyafhsvIARNTLVYII 1532
Q9ZT82       1439 AVFYTFSMGTRAHYFGRTILHGGAKYRATGRGFVVEHKGFTENYRLYARSHFVKAIELGLILivyashspIAKDSLIYIA 1518 thale cress
KRH22386     1406 SVFYTFSMGTRSHFFGRTILHGGAKYRATGRGFVVEHKSFAENYRLYARSHFVKAIELGLILtvyashstVATDTFVYIA 1485
XP_002317308 1441 SLFYTFSMGTRSHFFGRTILHGGAKYRATGRGFVVQHKSFAENYRLYARSHFVKAVELGVILtvyaanspLARNTFVYIA 1520
Q9S9U0       1431 SFFYTFSMGTRTHYFGRTILHGGAKYRATGRGFVVEHKKFAENYRLYARTHFIKAIELAIILlvyaayspLAKSSFVYIL 1510 thale cress
XP_004232875 1439 SLFFTYSMGTRAHFFGRTILHGGAKYRATGRGFVVQRKSFGENYRLYARSHFVKAIELGVILvvyasrspLTKDTFVYIA 1518
KRH10874     1462 SLFYTFSLGTRTHFFGRTILHGGAKYRATGRGFVVAHKSFAENYRLYARSHFVKGIELGVILivyaahspLARDTFLYIV 1541
ERN06585     1464 SVFYTFSMGTRTHFFGRTILHGGAKYRATGRGFVVQHKNFAENYRLYARSHFVKGIELGVVLtvyasysvVAANTLVYII 1543
XP_011271950 1580 ALLWFWITLVSMCLAPFIFNPHQFAFADFFVDYKDFIHWL-SKGNRKWH-SNSWVN--HVKQSRIRYTGLKKKVIghnse 1655
XP_002966392 1490 LTFSSWFLALTWILAPFVFNPSGFDWLKTVDDYEDFFNWVfYRGGVLVKaDQSWESwwDEEQDHLRTTGIWGKVF----- 1564
XP_003569838 1533 MMLSSWILVVSWIMAPFAFNPSGFDWLKTVYDFDDFMNWIwYPGGIFSKaEHSWEVwwYEEQDHLRTTGLWGKIL----- 1607
Q9ZT82       1519 MTITSWFLVISWIMAPFVFNPSGFDWLKTVYDFEDFMNWIwYQGRISTKsEQSWEKwwYEEQDHLRNTGKAGLFV----- 1593 thale cress
KRH22386     1486 MTFSSWFLVASWIMAPFVFNPSGFDWLKTVYDFEDFMNWIwNRQRVFAKaEQSWEKwwYEEQDHLKVTGFWGKLL----- 1560
XP_002317308 1521 MTISSWFLVISWIMAPFVFNPSGFDWLKTVYDFGGFNNWIwYSGGVFTKaEQSWETwwYEEQSHLRTTGLWGKLL----- 1595
Q9S9U0       1511 MTISSWFLITSWIISPFLFNPSGFDWLKTVNDFDDFIAWLwSRGGLFTKaDQSWFTwwNEEQEHLKTTGVWGKLL----- 1585 thale cress
XP_004232875 1519 MTISSWFLVVSWITSPFVFNPSGFDWLKTVYDFDDFMHWIwYNRGVFVKaDQSWETwwYEEQDHLRTTGLWGKLL----- 1593
KRH10874     1542 MTISSWFLVVSWIMSPFVFNPSGFDWLKTVYDFEDFINWIwYPGGPFKKaEYSWETwwYEEQDHLRTTGIWGKLL----- 1616
ERN06585     1544 MTLTTWFLVVSFIMSPFLFNPSGFDWLKTVYDFDDFMNWIwYTGGVFTKaEQSWETwwYEEQDHLKTTGIWGKVL----- 1618
XP_011271950 1656 sssgelkkshlyntfltELLLPFiqsvflffayTFINAQNGVrnveatnsVLRLIIL----VFAPILINSVTLVLIFALS 1731
XP_002966392 1565 -----------------EVILSL----------RFFFFQYGI--------VYQLGIAnhstSILVYLLSWIYVVVAFLLH 1609
XP_003569838 1608 -----------------EILLDL----------RYFFFQYGV--------VYQLKIAdgsrSIAVYLLSWICVAVIFGVF 1652
Q9ZT82       1594 -----------------EIILVL----------RFFFFQYGI--------VYQLKIAngstSLFVYLFSWIYIFAIFVLF 1638 thale cress
KRH22386     1561 -----------------EIILDL----------RFFIFQYGI--------VYQLGIAarstSIVVYLLSWVYVFVVFGIY 1605
XP_002317308 1596 -----------------EIILDL----------RFFFFQYGV--------VYHLDISggstSIVVYLISWTYMVVAVGIY 1640
Q9S9U0       1586 -----------------EIILDL----------RFFFFQYSI--------VYHLRIAenrtSIGVYLISWGCIIGIVAIY 1630 thale cress
XP_004232875 1594 -----------------EIILDL----------RFFFFQYGI--------VYQLHITggktSIGVYLLSWIIMVAVVAIY 1638
KRH10874     1617 -----------------EIILNL----------RFFFFQYGI--------VYQLGITgennSIAVYLLSWIVMVVLVAIY 1661
ERN06585     1619 -----------------EIILDL----------RFFFFQYGI--------VYHLGIAggskSIFVYLVSWIYVVVAVAYY 1663
XP_011271950 1732 CLIGPLM 1738
XP_002966392 1610 KILSFAH 1616
XP_003569838 1653 VLMSYAR 1659
Q9ZT82       1639 LVIQYAR 1645 thale cress
KRH22386     1606 VVVAYAQ 1612
XP_002317308 1641 VIIAYAS 1647
Q9S9U0       1631 ITTIYAQ 1637 thale cress
XP_004232875 1639 IAIAYAK 1645
KRH10874     1662 IIIAYAQ 1668
ERN06585     1664 VVMSYAR 1670
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