3ZRH,4BOP,5LRX


Conserved Protein Domain Family
OTU

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pfam02338: OTU 
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OTU-like cysteine protease
This family is comprised of a group of predicted cysteine proteases, homologous to the Ovarian tumor (OTU) gene in Drosophila. Members include proteins from eukaryotes, viruses and pathogenic bacterium. The conserved cysteine and histidine, and possibly the aspartate, represent the catalytic residues in this putative group of proteases.
Statistics
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PSSM-Id: 334900
View PSSM: pfam02338
Aligned: 17 rows
Threshold Bit Score: 112.139
Threshold Setting Gi: 75023271
Created: 23-Mar-2017
Updated: 23-May-2017
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
3ZRH_A   195 RTAGDCLLDSVLQATw--------GIYDKDSVLRKAL-----HDSLH----------------------Dcshwfytrwk 239 human
Q8N6M0   153 PSDGHCMYKAIEDQLke------kDCALTVVALRSQT-----AEYMQ----------------------S---------- 189 human
Q9VUN9   178 PSDGDCLYQSIRHQLiv-----naLPGHSVQELREET-----ANYVR----------------------A---------- 215 fruit fly
Q8W457   171 KPDGHCLYRAVENQLanr---sggASPYTYQNLREMA-----ASYMR----------------------E---------- 210 thale cress
Q19681   173 PADGDCMYNAISHQLqe------eGIEISVRKLRKRC-----GTYMR----------------------E---------- 209 Caenorhabditis elegans
P38747   173 QPDGHCLFASILDQLklrhdpkklDQDMDVMKLRWLS-----CNYVQ----------------------E---------- 215 Saccharomyces cerev...
Q9UGI0   438 RTAGDCLLDSVLQATw--------GIYDKDSVLRKAL-----HDSLHdcshwfytrwkdweswysqsfgL---------- 494 human
Q9VH90   513 RSAGDCLLDSAMQATwgvfdrdniLRR----ALADTLhq--cGHVFFtrwk--------------eyemL---------- 562 fruit fly
Q9N4T5   130 TGDGNCLLHAASLGMwgvhdrqlsLRE----TLYELLtngarKEAIRrrwkw------------venhmN---------- 183 Caenorhabditis elegans
EAY95593 180 kPDGHCLYRAVENQLsly---sreTTQYNYQELRQMT-----ANYMK----------------------E---------- 219 long-grained rice
3ZRH_A   240 dweswysqsfglHFSLREEQWQEDwafils-------------lasqpgASLE--------------------------- 279 human
Q8N6M0   190 ------------HVEDFLPFLTNPntgdmytpeef---qkycedivntaAWGG--------------------------- 227 human
Q9VUN9   216 ------------HKDSLISYMIHPetgdilndqqf---eqychdiakthAWGG--------------------------- 253 fruit fly
Q8W457   211 ------------HKTDFLPFFLSEtegdsnsgsaeerfekycrevestaAWGS--------------------------- 251 thale cress
Q19681   210 ------------HSEDFRPFIEDManmdsdsswaty-lggvenvaeiggVWGG--------------------------- 249 Caenorhabditis elegans
P38747   216 ------------HRDDFIPYLFDEetmkmkdide------ytkemehtaQWGG--------------------------- 250 Saccharomyces cerev...
Q9UGI0   495 ------------HFSLREEQWQEDwafils-------------lasqpgASLE--------------------------- 522 human
Q9VH90   563 ------------QASMLHFTLEDS-------------------------QFEEdwstllsla---------------gqp 590 fruit fly
Q9N4T5   184 ------------QSNGLALTLSEN-------------------------EWELewdvvlglssplprkqedngsnstdqi 226 Caenorhabditis elegans
EAY95593 220 ------------HAADFLPFFLSEgkvesgpdples-fkryceevestaAWGG--------------------------- 259 long-grained rice
3ZRH_A   280 -----QTHIFVLAHILRRPIIV-----YgvkyyKSFRGETLGYtRFQGvylpllwEQSFCWKSPIALGYTRGHF 343 human
Q8N6M0   228 -----QLELRALSHILQTPIEI-----I-----QADSPPIIVG-EEYS-------KKPLILVYMRHAYGLGEHY 278 human
Q9VUN9   254 -----HIELKAISSLLRVPIEV-----I-----QAEGAPTLLGqEEFG-------GSPLIICYHRHIYQLGAHY 305 fruit fly
Q8W457   252 -----QLELGALTHCLRKHIKV-----Y-----SGSFPDVEMG-KEYRsg----dDSSLMLSYHRHAFGLGEHY 305 thale cress
Q19681   250 -----ELELKACSMIFEKTIVV-----Y-----KQYGGRHTIG-EEYSsp----kDRALRVVFLRHAYSLGEHY 303 Caenorhabditis elegans
P38747   251 -----EIEILALSHVFDCPISI-----L-----MSGRPI-----QVYNec---gkNPELKLVYYKHSYALGEHY 301 Saccharomyces cerevisiae ...
Q9UGI0   523 -----QTHIFVLAHILRRPIIVygvkyY-----KSFRGETLGYtRFQGvylpllwEQSFCWKSPIALGYTRGHF 586 human
Q9VH90   591 gssleQLHIFALAHILRRPIIVygvkyV-----KSFRGEDIGYaRFEGvylplfwDQNFCTKSPIALGYTRGHF 659 fruit fly
Q9N4T5   227 yesleAIHVFALAHVLKRPVVVvsdtiL-----RNAKGEELSPvAFGGiylplecPPSQCHRSPLVLCYDSAHF 295 Caenorhabditis elegans
EAY95593 260 -----QLELGALTHCLKKHIVV-----Y-----SGSFPDVEMG-KEYKldsggkdGPSIRLSYHRHAYGLGEHY 317 long-grained rice
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