1MPR,1MPM


Conserved Protein Domain Family
LamB

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pfam02264: LamB 
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LamB porin
Maltoporin (LamB protein) forms a trimeric structure which facilitates the diffusion of maltodextrins across the outer membrane of Gram-negative bacteria. The membrane channel is formed by an antiparallel beta-barrel.
Statistics
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PSSM-Id: 334868
View PSSM: pfam02264
Aligned: 92 rows
Threshold Bit Score: 231.391
Threshold Setting Gi: 500092953
Created: 18-Mar-2017
Updated: 23-May-2017
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1MPR_A          3 FHGYARSGIGWTgs-------ggEQQ---CFQATGaqs---kyRLGNECETyAELKLGQEVWKEGDKSFYFDTNVAYSVN 69
gi 503970834   59 FHGYARAGLLVNddlngangtgpYMT---AAGALGap----vgRLGLEDDNyLEANLIHNRTMDDGSSARFHIMLADSVE 131
gi 229340097   45 lHGYLKSGLLLNgd-------gtRSN---SLGLFTnyg---kfRLGNEQNTkIELLPTIKITTDEGTWARVRANLTHETK 111
gi 501290981  115 FKGYARSGFLSRgskg----vwhNYPgafLTPAGAvdg--avgRLGIESNHyLELNFGKKWTFEDGSWARFRAMLAdgve 188
gi 505249190  121 FHGYARSGTVSNnem-----ftvKGVgpyITPAGNlgg--avgRLGLETDTyVEAKLMKNFRDPDGSWGQFGFMLAdgvn 193
gi 306526657  124 FHGYARSGLAIHdsvt----sskANIgpsMTPAGEtgg--hvgRLGNEDDTyLELKLEHRTKLDNGATTRFKVMMAdgqr 197
gi 1114533408 101 FHGYARSGVIMNdsaa----stkSga--yMTPAGEtgg--aigRLGNQADTyVEMNLEHKQTLDNGATTRFKVMVAdgqt 172
gi 503277872   98 FHGYARSGLLMNnsas----ktqGgp--tVTPAGEtgg--nigRLGNEPDTyVELNLEHKQTLTNGATTRFKVMLAdgqr 169
gi 983412349  109 FNAYARSGMLVNshgk----garGgp--gVSPASSlngdahvgRLGNEKDNyAELSFGKKLTFNDGSWARFKTMLAdgat 182
gi 640472917   91 FNAYARSGLLINsrgk----ggrGgp--gISPASSlnddahigRLGNEKDNyLELSLGKRMTFNDGSWAHFKTMIAdgak 164
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1MPR_A         70 qqndw-----estdPAFREANVQGKNLiEWLP-----GSTIWAGKRFYQRh-DVHMIDFYYWDISGPGAGIENIDLGF-G 137
gi 503970834  132 tnnewt---addsqLNVRQVYAELSNLsSFSGpf--eHATLWAGKRFDRDnfDIHFFDSDIVFLSGTGAGIYDVQFTQhW 206
gi 229340097  112 ctadwncvdgddhdIQFREGYVEMGGF-SFAP-----ESVFWAGKRYSSSntSSHQYDWEYIQYNGTGGGVDKIDVGF-A 184
gi 501290981  189 sqnd---wtggnngINFRQVYTEFGNLk--DMpswlsGATFWAGKRFDRDnfDIHFFDSDIVFLAGTGVGVYDAAIADgW 263
gi 505249190  194 snnd---wtggengVNVRWAYAELGNLpMFKGta-leSGSIWAGKRFDKKnfDIHFFDSDFIFLAGTGAGFYDAQVTPdW 269
gi 306526657  198 synd---wtastsdLNVREAFVELGSLpTFTGaf--kDTTLWAGKRFDRDnfDIHWIDSDVVFLAGTGGGIYDVKPVDgW 272
gi 1114533408 173 tynd---wtasssdLNVRQAFVELGNLpTFEGpf--kGSTLWAGKRFDRDnfDIHWIDSDVVFLAGTGGGIYDVKWNDsL 247
gi 503277872  170 tynd---wtasssdLNLRQAFTEIGHLpTFSGaf--kDATVWAGKRFDRDnfDIHWIDSDVVFLAGTGAGIYDMKWSDdA 244
gi 983412349  183 npdpw-vqdndshhLNIRQLYVEMGNFaEFTGpl--kRASIWAGKRFDRDnfDIHFTDSDIMFLGGTGGGINDVDWGSgL 259
gi 640472917  165 spdpw-iqdnnshhINIRQLYVEMGGFdEFSGaf--dNAYLWAGKRFDRDnfDIHFTDSDIMFLGGTGGGIYDVKLSNaL 241
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1MPR_A        138 KLSLAATRSTEAGGSYtfssqniydevKDTAN--DVFDVRLAg-LQTNPDGVLELGVDYGRANTTdgyk----------- 203
gi 503970834  207 KANFSIYGRDFGEIDSs-------------ST--DVENYIATm-NNRF--GNFQVMVSGMASSDNqnrd----------- 257
gi 229340097  185 KMDVGVYAFTPSGENSad--------pDDSSTqgYPEDISLNvwFKKIADSGLDFQVVGHTMEKSswr------------ 244
gi 501290981  264 KSNFSVYSRNFGNVGVynt--------------piVDDYIFTs-NNKF--GNWQLMLNGFAAAKNgqyanlpwsaatlas 326
gi 505249190  270 KTNLSVYGRDFL---------------NDTSE--SIKSYVVTs-NNYI--GNWQVMLNGMRATNNdeg------------ 317
gi 306526657  273 KSNLSIYGRSLGEITS-------------LDK--EIQNYIVTs-NNFV--GPFQFMLSGLRARNNdikentgsn-----n 329
gi 1114533408 248 RSNFSLYGRNFGDIAD-------------SSN--SVQNYIVSm-NNFA--GPVQMMVSGMRAKDNddrqdan-------- 301
gi 503277872  245 RSNLSLYGRTFGDIEN-------------NDN--TSQNYILSl-NNFA--GPLQLMVSGMRARDNddrvdte-------- 298
gi 983412349  260 RGDYSVYARNFGDLGSd----------NYADN--DIQNLLFTa-NHFY--GNWQLMTTVMTAQGNddlkdntstt----g 320
gi 640472917  242 KGNYSVYGRNFGDLGSn----------HYKDN--DIQNLMFTa-NHFY--DNWQLMLTGMAAQGNddlkdntstt----g 302
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1MPR_A        204 ----ladgA-----SKDGW--MFTAEHTQsm----lkGYNKFVVQYATDAmttqgkgqargsdgsssfteelsdgtkiny 268
gi 503970834  258 -----tdsAsptkrAETGVhaLFAYHGESfyg--lsdGFSKSGVLVGQGLgaelkgig---------------------- 308
gi 229340097  245 ------qnG-----PTSGL--GLTAVYNFdgfygltnGYSRITAQYGEGLaagdslgkn--------------------g 291
gi 501290981  327 savagttqR-----AETGMlaMLAYGDTSfyg--iapGVSKTALQFGWGLgaearvlg---------------------- 377
gi 505249190  318 -----dtgR-----ATRGYhgLLAYHAPSfyg--lgdGLSKFGVLYGHGLgaevkrlg---------------------- 363
gi 306526657  330 annvtntnA-----GDSGYhaLAAWHGDSfyg--lrdGTAKVALLYGHGLggevksig---------------------- 380
gi 1114533408 302 -gnlvkgdA-----ANTGVhaLLGLHNESfyg--lrdGTSKTALLYGHGLgaevkgig---------------------- 351
gi 503277872  299 -gnkvkgdA-----ANTGLhaLVGLHNDSfyg--lrdGSAKTALLYGHGLgaevksig---------------------- 348
gi 983412349  321 syalrsdnT-----AKNGYyaMLALHDKQqfyg-lapGVSESALQYGVGLgaearqpg---------------------- 372
gi 640472917  303 syalrsdnT-----AKNGYyaMLAYRDKQqfyg-lakGVSETALQYGEKLgaearqpg---------------------- 354
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1MPR_A        269 ankvinnnGNMWRILDHGAISLGdKWDLMYvGMYQNIDw-------DNNLGTEWWTVGVRPMYKWTPIMSTLLEVGYDNV 341
gi 503970834  309 sngdlnddAKAMRVFSYGVTRFAdHWRIAPaVMAEYSQdr-----iKTNDEFKWASVNVRLAQELTQNFEMVYEGTYQYM 383
gi 229340097  292 wgfgnakdAKSARIVFDGLANLSeSWELSTfAFYQSDSdyapwagtKTGADRDIYAIGVRPHNQITKNFAMQYELGYEHI 371
gi 501290981  378 adgnlahdAKTVRLATYGVTDLApDLHFAPaVMAQISQdr-----yVDGDSYKFITLNGRLMQDITRSFAMQYELTYQYA 452
gi 505249190  364 avgnllddARALRLMSFGIADIAqNWKVSPaVMAEVSKdr-----fNKGDDYKWASANLRLINSINKNFAMQYEGSYQYM 438
gi 306526657  381 sdgnltqnANTWRLATYGTTALNkTWSFAPaILAQSSKdr-----yVQGDDYRWVTFNARFIQEITENFALAYEGSYQYM 455
gi 1114533408 352 sdgalrpgANTWRFASYGTTPLSdRWFIAPaVLAQSSKdr-----yVDGDSYQWATLNLRLIQEVTQNFALAWEGSYQYM 426
gi 503277872  349 sdgallpeANTWRLASYGITPLGgGWHIAPaLLAQSSKdr-----yVKGDSYEWATANLRLIQEITQNFEMQYEGSYQYM 423
gi 983412349  373 sdgdltenAASLRFASYGILPLGkNWQLAPsVIAQHSEdr-----yRDGDRYDWATFNLRVSQGISAHFALLYEASWQYM 447
gi 640472917  355 sdgdltenAKSLRFASYGILPAWqNWEFAPsVIAQHSEnr-----yQDGDRYDWVSFNFRASQALTQHFALLYEASWQYM 429
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1MPR_A        342 Ksqqt--------------gdrnNQYKITLAQQWQA---GD--SIWSRPAIRIFATYAKwdek----------------- 385
gi 503970834  384 Dldnsv------------dqakgSFYKATIAPTFKL---ATsaGFFDRPEIRFAVSYVDwssald--------------- 433
gi 229340097  372 Kedvad-------------gadgGFYKATIAPTLML---ET--GFWARPQIRAFVTYAKwddg----------------- 416
gi 501290981  453 Dlapngytayg---lrtgqhvngSIGKVTIAPTFYLdqlGL--GLMTRPQLRVFGSYIMwdkklhnfslsdafgpqsgsy 527
gi 505249190  439 Dldstf------------skakgDFYKLTVAPTFKLd-tGA--GFFARPELRLFASWMKwdkqlngftydgs-------- 495
gi 306526657  456 Nldpqgyl--------srnqvsgGFYKLTFAPTFKVg-dIS--NLLSRPELRIFASYMDwdkrldnyasd---------- 514
gi 1114533408 427 Dlqpegyn--------drhavngSFYKLTFAPTFKVg-sIG--DFFSRPEIRFYTSWMDwskkldnyand---------- 485
gi 503277872  424 Dlrpkgyn--------srnavsgSFYKLTVAPTLKAs-dVG--EFLKRPEIRLFATWMDwdhrldnyasd---------- 482
gi 983412349  448 DlnpngrsyryndnvyqyqavrgDFYKLTFAPTFKVg-dVL--DIKARPEIRFFATWMNwdkaldryain---------- 514
gi 640472917  430 DlnpngrrynsdqgiktyqpvegGFYKLTFAPTFKVg-dVF--DIKARPEIRVFATYMNwdkeldryain---------- 496
                         490       500       510       520
                  ....*....|....*....|....*....|....*....|....
1MPR_A        386 --wgyiKdgdnisryaaatnsgistnsrgdSDEWTFGAQMEIWW 427
gi 503970834  434 -dyavsLdsdas--------------tmgsGGETVFALQMETWF 462
gi 229340097  417 --asskIdsgyt--------------rngeTDTLNFGIQAEVWF 444
gi 501290981  528 ltnvrlSd---------------------kAGSFLFGGQMEIWY 550
gi 505249190  496 ------------------anegfgatkfkgSSKWLVGAQMEVWF 521
gi 306526657  515 --------------------dafgstgfkaGGEWTFGVQMETWF 538
gi 1114533408 486 --------------------dalgsngfksGGEWSFGMQMETWF 509
gi 503277872  483 --------------------dafgsngfkaGGEWNFGVQMETWF 506
gi 983412349  515 --------------------ddfgskgftaGGTWNFGVQTEIWF 538
gi 640472917  497 --------------------ddfgskgftaGGNWNFGVQAEIWF 520
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