Conserved Protein Domain Family
zf-TAZ

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pfam02135: zf-TAZ 
TAZ zinc finger
The TAZ2 domain of CBP binds to other transcription factors such as the p53 tumor suppressor protein, E1A oncoprotein, MyoD, and GATA-1. The zinc coordinating motif that is necessary for binding to target DNA sequences consists of HCCC.
Statistics
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PSSM-Id: 307990
View PSSM: pfam02135
Aligned: 209 rows
Threshold Bit Score: 28.9087
Threshold Setting Gi: 0
Created: 16-Jul-2016
Updated: 4-Aug-2016
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

pfam02135 is a member of the superfamily cl02660.
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                            10        20        30        40        50        60        70        80
                    ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 408360352    406 IQQQLVLLLHAHKCSQREkenrdfaaknqppphaaCtLPHCSTMKEVLTHMTSCN---------------VgrL-CHsdt 469
149_pfamImport    1 ILRCIQTLRHAHHCHDAS-----------------CsRTNCQKMKRVLLHPMHCQrq------------aN--GgCP--- 46
147_pfamImport    1 ILRSIQSLRHARHCGDAN-----------------CpRNDCQKLKRVVLHATRCQrk------------aI--GgCP--- 46
89_pfamImport     1 IQRCIQFLRHARQCGDAS-----------------CpQASCLKMKRVMEHTRSCErk------------tN--GgCG--- 46
71_pfamImport     1 IQQCIQNLVHSAKCRDAN-----------------CnRPNCQKMKKIIEHSKRCAklkq-------kqknN--QqCN--- 51
175_pfamImport    1 LQKYEQALVHAASCRDGN-----------------CrIKSCILMKQFIQHLQDIIklknkpthknnnhskN----CG--- 56
99_pfamImport     1 LSRLVKALGHGCSCRDAN-----------------CrVFACKTMKSNVQHFRVHAaa------------aR--NqCN--- 46
92_pfamImport     1 LSRWVKALGHSCYCRDAN-----------------CrVYACKTMKYQVQHFRVHSt-------------dR--NqCS--- 45
183_pfamImport    1 INSYISSLVHASHCRDAN-----------------CrLNVCQKMKRFMQHIRTCKrr------------qD--NsCK--- 46
91_pfamImport     1 IEGCIRSLLHACQCRDAN-----------------CrMQTCAQMKRVLCHTRNCTkk------------aT--NsCL--- 46
                            90       100       110
                    ....*....|....*....|....*....|....*..
gi 408360352    470 tqttkkcsvaHCASSRQIIA-HWKNCsReD-CPV--C 502
149_pfamImport   47 ----------VCKQLITVCYyHAKSCqR-NpCPVpfC 72
147_pfamImport   47 ----------VCKQLLALCCyHAKECqE-NpCPIplC 72
89_pfamImport    47 ----------VCKQFIALCCfHAKQCqE-SpCPIpyC 72
71_pfamImport    52 ----------VCKQFIALCCyHAKHCeE-KsCKImyC 77
175_pfamImport   57 ----------TCSQMARLCLyHAKMCkErNkCPVpsC 83
99_pfamImport    47 ----------VCRSLSFLCYyHSKTCqE-LkCPVplC 72
92_pfamImport    46 ----------VCRFIYYLCCyHSKTChE-LkCLVplC 71
183_pfamImport   47 ----------VCKQLLLLCWtHAKQCkE-SkCPVpfC 72
91_pfamImport    47 ----------LCQQLLSLLWhHARSCeE-SkCPVpfC 72
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