4F38


Conserved Protein Domain Family
Rho_GDI

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pfam02115: Rho_GDI 
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RHO protein GDP dissociation inhibitor
Statistics
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PSSM-Id: 307981
View PSSM: pfam02115
Aligned: 41 rows
Threshold Bit Score: 215.571
Threshold Setting Gi: 576040488
Created: 15-Jul-2016
Updated: 4-Aug-2016
Structure
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Program:
Drawing:
Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4F38_B        11 LAQIAAENEEDEHSvnYKPPAQKSIQEIQELDK------------------------DDESLRKYKEAL-LGRvaV---S 62
gi 410902049  11 LAEIAAANEESEGSvnYKAPAQKSLQEIQELDK------------------------DDDSLRRYKEAL-LGKasV---V 62
gi 340383732  11 LPPEVPEGEEDETTpgYKAPKKVDLQTIQQMDA------------------------DDESLVKYKQQL-LGQtaGildE 65
gi 573028148  59 DPTIADEELATTATagYKVGEKKSLAEYSQLDA------------------------EDESLARWKASLgIGAstG---A 111
gi 313225538   8 eqlkalaikeeeeeskYKAPAEKSIEELQKLDE------------------------SDEALKRYKEQL-LGNleSaksA 62
gi 891592738  10 NGTNELDDEFVDNSvpVSLGEKKTLNEYVHMDA------------------------EDPSLTKWKESLgISNkgYs--- 62
gi 562885093   7 eAHLEEDDDELDEKlnYKPPPQKSLKELQEMDK------------------------DDESLAKYKKTL-LGDgpV---V 58
gi 357627405 195 ARTPEDDTEEEEIKssYKPPPEKSIEEILSADQ------------------------EDESLRKYKEAL-LGQaqTgpvI 249
gi 195428573   8 QHHADDHHDEDVHDanYQAPPEKTIEEIMAADQ------------------------EDESLRRYKEAL-LGAaqAekiI 62
gi 576040488   2 ashqeddllpenttgykltqpkHTLEEYKKMESsvieqntnmspdrkiqfvvpepheNDESLQRYKASLgLGNgk---dL 78
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
4F38_B        63 aDPNVPN-VVVTRLTLVCSTAPG-PLELDLT--GD--LESf---kKQSFVLKEGVEYRIKISFRVNREIVSGMKYIQHTY 133
gi 410902049  63 tDPKLPN-VHVTRMTLMCDTAPG-ALVLDLT--GN--LENi---kKSTFVLKEGVDYKIKITFKVNKEIVSGLRYTQTST 133
gi 340383732  66 gGSN-----VLLKQMIIAPEGRD-EITLDLT--GD--LSKf---kKNPVVIKEGTQYRLKIVFRVQREIVSGLRYNHGAF 132
gi 573028148 112 vDPNAPK-LSLHALSLVSSSAPGgSVSINLQ--QS--KEQlaqfkQNPLNVKEGVEYSVKIRFSVGSDILSGLKYVQVVK 186
gi 313225538  63 ---DARR-VVVKKILLNSKDLPS-PLIMDLS-------DTs---kKQSFKIKEGAEYTIGIEFKVNNEIVSGLRYNQVVT 127
gi 891592738  63 -PPNDPRtVVIEQLSLLVNGR-D-PIHVDMQdeGS--VEQi---qKKGFVIKEDSEYRIAVRFRVQHELISGLRYVQVVR 134
gi 562885093  59 aDPSVPN-VVVTRLTLVCDSAPG-PITMDLT--GD--IEAl---kKELFVLKEGVEYRVKINFKVNRDIVSGLKYVQHTY 129
gi 357627405 250 vDANDPR-KVIVKKLALCVAERD-DLELDLS--GD--LTDl---kKQVFVIKEGVQYKIRIDFIVQREIVHGLKYVQKTY 320
gi 195428573  63 vEPNDPR-KVIVKKLALVVEGRD-DMELDLT--GD--ISQl---kQQVFVIKEGVQYKVRIDFIVQREIVHGLKYVQKTY 133
gi 576040488  79 sDPNDPR-VCIILSLTMESPGRE-PVVIDLS--EPgaLENl---kKKPFKIKEGANFTMSAKFKVQHEILSGLHYVQVIK 151
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
4F38_B       134 RKGVKI--DKTDYMVGSYGPRA-EE---YEFLTPMEEAPKGMLARGSYNIKSRFTDDDRTDHLSWEWNLTIkKE 201
gi 410902049 134 RKGVKV--DKTDYMVGSYGPRPeEE---YEYVTPVEEAPKGMLARGTYTIKSKFTDDDKHDHLSWEWNLTIkKD 202
gi 340383732 133 RKGIKV--DKSNLMVGSYGPKT-EA---HVFTTPVEDAPSGMLARGDYTIKSKFTDDDKNPILEWEWVLKIaKD 200
gi 573028148 187 RAGIKV--DKMEEMIGSYGPRA-EP---YEKTFASSEAPSGMMARGNYSVRSRVVDDDNNVFADWEWAFKIaKD 254
gi 313225538 128 RKGIKV--DKMNLMVGSYAPRA-DD---YTFTTELDEAPSGMLARGSYKVQSKFIDDDKTEHAVWEWQFDIaKK 195
gi 891592738 135 RVGMTV--DKSSTMIGSYSPNE-TP---YEFTTEPEEAPSGFLARGHYEAIGKFIDDDQVVHHVVQWSFDVtKN 202
gi 562885093 130 RTGLKV--DKATFMVGSYGPRS-EE---YEFLTPTEEAPKGMLARGTYHNKSFFTDDDKHDHLTWEWNLSIkKD 197
gi 357627405 321 RLGVPV--DKMTHMVGSYPPKT-EI---QSYTTPPEDAPSGMMARGSYTVNSLFTDDDKNVHLQWEWSFEIkKD 388
gi 195428573 134 RMSLPV--DKMAHMVGSYPPKK-EI---QNYLTPPEEAPSGMISRGTYSVSSVFTDDDKHIHLKWDWTFEIkKD 201
gi 576040488 152 RHGIRIpgGKSDEMIGSYAPNT-DKqpvYVKKFQEETAPTGWAVRGKYDVTSSFVDDDQKTHLKFDWAFEIdKD 224
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