2E9H,3J81,2D74,2NXU


Conserved Protein Domain Family
eIF-5_eIF-2B

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pfam01873: eIF-5_eIF-2B 
Click on image for an interactive view with Cn3D
Domain found in IF2B/IF5
This family includes the N-terminus of eIF-5, and the C-terminus of eIF-2 beta. This region corresponds to the whole of the archaebacterial eIF-2 beta homolog. The region contains a putative zinc binding C4 finger.
Statistics
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PSSM-Id: 334720
View PSSM: pfam01873
Aligned: 202 rows
Threshold Bit Score: 114.894
Threshold Setting Gi: 269861084
Created: 18-Mar-2017
Updated: 23-May-2017
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2E9H_A         16 VSDQFYRYKMPRLIAKVEGKGngiKTVIVNMVDVAKALNRPPTYPTKYFGCELGAQTQFDvK-NDRYIVNGSHEANKLQD 94
gi 156389677   10 nmDQFYRYKMPKLIAKVEGKGngiKTVIVNMPDIAKALSRPPSYPTKYFGCELGAQTQIDlK-NERYIVNGAHQADKLQE 88
gi 1073706285  10 lTDQFYRYKMPKIIAKVEGKGngiKTVLVNMTEVAKALNRPPTYPTKYFGCELGAQTQLDaK-NDRYIVNGAHEASKLQD 88
gi 196007526    9 NNDPYYRYKMPRIIAKVEGKGngiKTVIVNMTEIAKSLQRPPSYPTKYFGCELGAQTQLDsK-NDRYIVNGSHDGSKLQE 87
gi 1087812008  10 VQDVFYRYKMPCIIAKVEGKGngvKTVIVNMSDVAKAIGRPATYACKFFGCELGAQTQFDlK-NDRYIVNGSHENTRLQD 88
gi 1005939517  10 lSDQFYRYKMPKLLAKVEGKGngiKTVIVNMVDIAKSLNRPPMYPTKYFGCVLGAQVNYDpK-NERYIVNGSHESNKLQD 88
gi 313229326   12 VNDPFYRYKMPGIVAKVEGQGngiKTVIVNMVDIARALNREPVFPTKFFGMELGAQTQID-EkNDRFIVNGSHDEAKLQD 90
gi 340371745   10 NTDPYYRYKMPLLIAKVEGKGngiKTVIVNMVEIGKALQRPPSYPCKYFGCELGAQTQMDpK-NGRYIVNGAHEGPKLQD 88
gi 260830485    9 VQDQFYRYKMPRIIAKVEGKGngiKTVIPNMTEVAKALSRPATYTTKFFGCELGAQTQLDvK-NDRYIVNGAHDAAKLQD 87
gi 725581540    9 VSDQFYRYKMPRLIAKVEGKGngiKTVIVNMVDVAKALNRPPTYPTKYFGCELGAQTQFDvK-NDRYIVNGSHEANKLQD 87
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|
2E9H_A         95 MLDGFIKKFVLCPECENPET---DLH--Vn-pKKQ--TIgNS--CKACGY 134
gi 156389677   89 ILDGFIERFVLCSSCENPET---VLV--V---DTRkeRIgQN--CKACGH 128
gi 1073706285  89 ILDGFIRRYVLCASCDNPET---VLG--V---LQRkgIItTK--CRACGH 128
gi 196007526   88 ILDGFIKKFVLCPECENPET---DLS--V---DSR--KEkIKtsCLACGY 127
gi 1087812008  89 MLDIFIKKFVLCNECENPET---TMI--V---KRG--TIgLV--CKACGN 126
gi 1005939517  89 LLDGFIQKYVLCPSCHNPETvlgVLT--K---KN---IItTS--CKACGy 128
gi 313229326   91 ILDVYIKKFVLCSKCENPET---TLT--V---KRD--DIiEC--CKACGH 128
gi 340371745   89 LLDGFIKNFVLCEECENPET---NLV--VqtgKNR--Iv-QT--CIACGH 128
gi 260830485   88 LLDIFIKKFVLCQECDNPET---NLKvfV---KKG--VIaQH--CIACGH 127
gi 725581540   88 MLDGFIKKFVLCPECENPET---DLH--VnpkKQT--IG-NS--CKACGY 127
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