3VI3,3VI3,3V4P,5E6R


Conserved Protein Domain Family
FG-GAP

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pfam01839: FG-GAP 
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FG-GAP repeat
This family contains the extracellular repeat that is found in up to seven copies in alpha integrins. This repeat has been predicted to fold into a beta propeller structure. The repeat is called the FG-GAP repeat after two conserved motifs in the repeat. The FG-GAP repeats are found in the N-terminus of integrin alpha chains, a region that has been shown to be important for ligand binding. A putative Ca2+ binding motif is found in some of the repeats.
Statistics
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PSSM-Id: 334703
View PSSM: pfam01839
Aligned: 186 rows
Threshold Bit Score: 29.4203
Threshold Setting Gi: 81719014
Created: 17-Mar-2017
Updated: 23-May-2017
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
3VI3_A 285 FGYAVAAT-DVNGDGLDDLLVGAPllmdrTp-DGRPQevGRVYVY 327  human
Q82EZ0 408 FGSTVRLT-DLTKDGKPDLVVGAP-----GedNSTGG----IWVF 442  Streptomyces avermitilis
Q8Z036 307 SDWTASIG-DFNGDGRTDIFWNn---------TTTGE--NTAWLM 339  Nostoc sp. PCC 7120
Q7NLR2 225 NWRIAGAG-DFNGDAKPDILWRNY-----Gs-GSEAGa-HRVWYL 261  Gloeobacter violaceus
Q7NLX4 936 NWQVGGVG-DYNGDGKVDILWRn---------GATGQ--NIVWIM 968  Gloeobacter violaceus
Q7NDL9 930 LNWRIGGSgDYNGDGKADILWRn---------GATGA--NTVWLM 963  Gloeobacter violaceus
Q7NF97 279 AGWQLNAFgDYSGDGKPDLVWRn---------YTTGA--NTLWLM 312  Gloeobacter violaceus
Q7NDI7 777 LNWRIGGTdDFNADGKLDILWRn---------QATGQ--NSVWLM 810  Gloeobacter violaceus
Q7NL49 700 RNWTIGGAsDFTADGKTDILWRn---------GATGQ--NTIWIM 733  Gloeobacter violaceus
Q82EY9 159 FGLSIAAA-DFTGDGKPDLAVS-------Tq-SSTGSr-YKIRLI 193  Streptomyces avermitilis
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