1C5A


Conserved Protein Domain Family
ANATO

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pfam01821: ANATO 
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Anaphylotoxin-like domain
C3a, C4a and C5a anaphylatoxins are protein fragments generated enzymatically in serum during activation of complement molecules C3, C4, and C5. They induce smooth muscle contraction. These fragments are homologous to a three-fold repeat in fibulins.
Statistics
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PSSM-Id: 307779
View PSSM: pfam01821
Aligned: 114 rows
Threshold Bit Score: 30.2934
Threshold Setting Gi: 537238540
Created: 13-Jul-2016
Updated: 4-Aug-2016
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
1C5A_A         21 CCYDGAYR-NDDETCEERAARIkI-GPKCVKAFKDCC 55   domestic pig
P37889        435 CCAAGQQWaIDNDECQEIPENG-AqSDICRIAQRQCC 470  house mouse
XP_012399157  480 CCAAGQQWaIDNAECTEIPVSG-AdGDVCRIAQKQCC 515  Tasmanian devil
CAF96111        4 CCQDGRNRgNNGHDCTIIPAF--SsSYTCRIAQEQCC 38   spotted green pufferfish
XP_011611780   80 CCQDGRNRgDHGQDCTIIPNL--SsSHMCRIAQERCC 114  torafugu
O42182         29 CCEDGKKRgLESQDCSSLPLI--SeSTTCRVVQEQCC 63   zebrafish
XP_015208785   28 CCRNGRDWaTQKQDCSTLPLM--SeLPTCRIAQEQCC 62   spotted gar
XP_003221476   33 CCTHGYEWaSQKRDCSSLPLN--PdSKECSIAQEQCC 67   green anole
AAC05388       33 CCDKGVEWaNKNRICTSLPLI--SeSRECSMTQVQCC 67   chicken
XP_005994038   32 CCTQGQEWaTRTRVCSSLPFV--SdVQECRFAQQQCC 66   coelacanth
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