3TKA


Conserved Protein Domain Family
Methyltransf_5

?
pfam01795: Methyltransf_5 
Click on image for an interactive view with Cn3D
MraW methylase family
Members of this family are probably SAM dependent methyltransferases based on Escherichia coli RsmH. This family appears to be related to pfam01596.
Statistics
?
PSSM-Id: 307764
View PSSM: pfam01795
Aligned: 14 rows
Threshold Bit Score: 414.038
Threshold Setting Gi: 8134809
Created: 14-Jul-2016
Updated: 4-Aug-2016
Structure
?
Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3TKA_A       38 NYKHTTVLLDEAVNGLNI--------------RPDGIYIDGTFGRGGHSRLILSQLGEEgRLLAIDRDPQAIAVAKTi-- 101
gi 42560202   1 MFHHISVMLNETIDYLNV--------------KENGVYIDCTLGGAGHALYLLNQLNDDgRLIAIDQDQTAIDNAKEvlk 66
gi 30315982   4 EFHHVTVLLHETIDMLDV--------------KPEGIYVDATLGGAGHSEYLLSKLSEKgHLYAFDQDQNAIDNAQKrla 69
gi 2496335    4 NQPHKSVLLDEVIHNLNI--------------KGDGNYLDLTVGFGGHSQHILEQLTTG-TLTGNDMDKDSITFCTElfk 68
gi 1175483    9 SSEHITVLLHEAVNGLAL--------------KENGIYIDGTFGRGGHSRFILSQLSSNgRLIAVDRDPRAIAEAHKi-- 72
gi 8134809   26 ALCHQPVLVQECLTLLEPaivgisrgadstrdGAGAFFIDGTLGDGGHTQAFLHAYPAL-RALGVEIDPSMLARARArlt 104
gi 8134813   18 DFHHVSVLPTALVEGLEP--------------KPGGYYLDATVGAGGHSERLLKLGIPL-ALTMIDRDVQAIAAAMErlq 82
gi 8134826    2 EVLHKPVLLRESVEFLTE--------------NGGKIYVDCTLGGGGHAKEILKKRKDI-FLIGIDRDEEAIEIAKEnlk 66
gi 8134806    4 NAFHFPVLLDAICKLIEDlp-----------vKSDLIYIDSTLGEGVHAKAILEKYDFL-SLVGIERDPQILERARQfls 71
gi 20138894   4 SIPHIPVLVKESLSLFRD--------------RNPVVFCDVTVGAGGHAEAFLTEFPSIeRYDGSDRDLSALALSENrll 69
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3TKA_A      102 ------dDprFSIIHGPF-SALGEYVAERDl--IG---------------KIDGILLDLGVSSPQLDDAERGFSFM-RDG 156
gi 42560202  67 d---hlhK--VTFVHSNF-RELTQILKDLN---IE---------------KVDGIYYDLGVSSPQLDIPERGFSYH-HDA 121
gi 30315982  70 p---yieKgmVTFIKDNF-RHLQARLREAG---VQ---------------EIDGICYDLGVSSPQLDQRERGFSYK-KDA 126
gi 2496335   69 d------kknVVLVHDNF-ANFFNHLKQLK---VT---------------KFDGILIDLGVSSYQLDKPERGFSFK-HAG 122
gi 1175483   73 ------qDlrFQIEHNSF-SHIPEICDKLNl--VG---------------KIDGILLDLGVSSPQLDEAERGFSFM-KDG 127
gi 8134809  105 p---fgkR--LRYVLGWSdVFFASAYASAPaspATgrtaagaagvpgaypAPQAVLLDLGISFFHYRGAMRGFSFA-EEH 178
gi 8134813   83 plvadrkDisINTWQGNF-ADFPGQLE-----------------------QFDGIIADLGVSSPQLDQGDRGFSFR-HTA 137
gi 8134826   67 e---fegR--FSIYKANF-KDLDLVLKEEG---ID---------------KVDGFLFDLGVSMYQL-KGERGFTFQ-EDQ 120
gi 8134806   72 i---feeR--ITYFNDWFdNFFVNYPLNV---------------------KANFILVDLGISMFHYKGSKKGFSFL-EDE 124
gi 20138894  70 p---fkdR--VRLRHASF-EEVDTLTSDG---------------------TYDGVLADLGVSSMQLNNLERGFSFQgEDH 122
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3TKA_A      157 PLDMRMDPTRGQ-SAAEWLQTAEEADIAWVLKTYGEERFAKRIARAIVE------RNREQPMTRTKELAEVVAAATPVKD 229
gi 42560202 122 TLDMRMDQTQEL-TAYEIVNNWSYEALVKIFYRYGEEKFSKQIARRIEA------HREQQPITTTLELVDIIKEGIPAKA 194
gi 30315982 127 PLDMRMNQDASL-TAYEVVNHYDYHDLVRIFFKYGEDKFSKQIARKIEQ------AREVKPIETTTELAEIIKLVKPAKE 199
gi 2496335  123 PFDMRMHQSDRVpTALDILERLSEEELTHVLKKFGEIAHPKPIAKALKTl----iNNTKNP--TTVEVAETVKAAASNFE 196
gi 1175483  128 PLDMRMDTTQGL-SAEEWLKQVSIEDLTWVLKTFGEERFAKRIATAIVDfnksavKNGTEFLSRTSQLAELISQAVPFKD 206
gi 8134809  179 MLDMRLDPQASQ-TAADLLNRLPQARLAQLFFEGGEERYARRIAQAVCA------QRRQAPFCSARAFAEVVARVVPPMR 251
gi 8134813  138 PLDMRMDQSQDL-TAAEIINHWSEKDLARIFYEYGEERLSRRIARQIVE------QR---PFQTTTDLAEAITKWVPGKY 207
gi 8134826  121 PLDMRMDKEQTL-TACKVVNNYPERELIRILKEYGEEKFAVRIAKAIVQ------RRKKKPIETTGELVDVILSVVPEYY 193
gi 8134806  125 PLDMRLCSSSCKiSAAEIVNTYSKYDLEALIYDLSNEHYSRRISKAIVE------YRKIKKIETTKELQSIISKVYPFSK 198
gi 20138894 123 PLDMRMDTSRGM-TASEVLNSLREEEIGEIFRNYGEEPLWRSAAAAVVH------FRKKKKILTVKDLKDATSGVFPSYR 195
                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
3TKA_A      230 KFK--------------HPATRTFQAVRIWVNSELEEIEQALKSSLNVLAPGGRLSIISFHSLEDRIVKRFMRENSRGPQ 295
gi 42560202 195 RRKg------------gHPAKRVFQALRIAVNDELSAFEDSIEQAIELVKVDGRISVITFHSLEDRLCKQVFQEYEKGPE 262
gi 30315982 200 LKKk------------gHPAKQIFQAIRIEVNDELGAADESIQQAMDMLALDGRISVITFHSLEDRLTKQLFKEASTV-E 266
gi 2496335  197 KYKs------------rNYLAKVFQAIRIYLNRELESLEIVLQHIPKLLNNKGRFLVIVFHSLEEKLVRNYIFKLTH--F 262
gi 1175483  207 KHK--------------HPATRSFQAIRIFINSELDELESLLNSALDMLAPEGRLSIISFHSLEDRMVKHFMKKQSKGED 272
gi 8134809  252 TARfgkrrgvlgvlpklHPATKAFQALRIAVNRELERLPRLLTAAFTALAPGGRLAVISFHSREDRIVKVHFRHWAKRCS 331
gi 8134813  208 RHGr------------iHPATRTFQGLRIAVNDELGSLEKFIAQAPHWLKSGGKFGIISFHSLEDRIVKHRFRETEN--- 272
gi 8134826  194 KHGk------------iHPATRTFQAIRIEVNKELESLKEALEKTPYHFNSKGRLVVITFHSLEDRIVKHFIKEKEK--- 258
gi 8134806  199 Vk--------------iNPATKTFQALRIYVNDELARLKRSLPFWVENLAKDGILAIITFHSIEDRIVKDFFRSLSCD-- 262
gi 20138894 196 LRKk------------iHPLTLIFQALRIYVNQEGAQLKVLLDSAFRWLRPGGRLAVISFCSLDDRPVKWAFREAEA--- 260
                       330       340       350       360       370
                ....*....|....*....|....*....|....*....|....*....|...
3TKA_A      296 V-PAGLPMTEEQLKKlggrQLRALG-K-LMPGEEEVAENPRARSSVLRIAERT 345
gi 42560202 263 V-PRGLPVIPEAYTP----KLKRVNrKpITATEEDLDDNNRARSAKLRVAEIL 310
gi 30315982 267 V-PKGLPFIPDDLKP----KMELVSrKpILPSAEELEANNRSHSAKLRVVRKI 314
gi 2496335  263 VqPPELPVKLTP-------PFELITkKpILPTEQEIKTNPRVRSAKLFVIEKK 308
gi 1175483  273 I-PKGLPLREDQIQRn--qKLRIIG-KaIQPSDAEIQANPRSRSAILRVAERI 321
gi 8134809  332 C-PARVPICSCGGVA----RASLITkKpLVPSCVERAANAASRSATLRVIEKR 379
gi 8134813  273 --------------------LRVLTkKpIIAGEEEQRQNPRARSAKLRWAEKI 305
gi 8134826  259 ---EGI--------------FRIITkKpVTPSEEEIRENPASRSAKLRVAEKI 294
gi 8134806  263 -------------------LYAKISkKpIMPSFDEIKKNKPSRSAKLRVVKKL 296
gi 20138894 261 ---RGL--------------GKILTkKvIMPSYEETRMNPRSRSAKLRCFEKS 296
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap