3FOZ


Conserved Protein Domain Family
IPPT

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pfam01715: IPPT 
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IPP transferase
This is a family of IPP transferases EC:2.5.1.8 also known as tRNA delta(2)-isopentenylpyrophosphate transferase. These enzymes modify both cytoplasmic and mitochondrial tRNAs at A(37) to give isopentenyl A(37).
Statistics
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Aligned: 1233 rows
Threshold Bit Score: 71.6568
Threshold Setting Gi: 124457024
Created: 18-Jun-2019
Updated: 18-Jul-2019
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
3FOZ_A    46 IYKGMDIGTAKPNA-EELLAAPHRLLDIRDP-----Sq--AY--SAADF-RRDALAEmaDITA---A-GRIPLLVGGTML 110 Escherichia coli K-12
Q6YQU8    38 MYQKYDIGTAKITL-EEAQGIKHHLLDFLAP-----Gt--NY--SIYHF-QKDARKKi--------EeTPLPLFVGGSGL 98  Onion yellows phyto...
B3R0E8    38 IYKKYNIGSAKITF-AEQKSIKHHLLDLKEP-----De--VY--TIYDF-QRDCRKIi--------SnVRLPFLVGGSGL 98  Candidatus Phytopla...
EFC40682  53 MYKECSIGSNKIKE-EEMQGISHHLVNNVSLekcahDkthQY--TVQQFyVDAHEKCl-EILA---R-GKLPILVGGSAF 124 Naegleria gruberi
EGC28765  49 IYKNLSVGSNS-NDtINQKEVPFHLYNFLDI-----Nn-sKF--NVYNY-FQHAKKAinEIVD---R-GNTPIIVGGCGF 114 Dictyostelium purpu...
Q556J1    50 IYKHLTIASNKVTDt---NGIPHHLIDMLDL-----Dd-nNF--CLFDY-YRLAKNTikDVLS---R-GRVPIVVGGCGF 113 Dictyostelium disco...
A0CSW7    38 IYKNWPISSNWPKK-IDN----YELIGKYDG----------LkqTITSY--HYKMEVm-EIL----KqRDNAILEGGCCF 95  Paramecium tetraurelia
CDA37368  36 VYQGFDIGSAKSTP-KELEGIENYFIDSIPW-----Gq--AM--TVFEF-QTNGRQIi-N--SfkdR-NVDGVIVGGTFL 100 Clostridium sp. CAG...
CDE08488  38 VYKGMDIGTAKVTT-EEMEGIPHHLLSFVPV-----Tr--NY--TVFDY-QKDGRQVidEIQS---R-GKNIILVGGTGL 102 Bacillus sp. CAG:988
CDE15418  36 VYKELNIGVAKPTK-EELDGLTYHLIDEVPL-----De--EM--NVKVY-QERARAIldKYVS---E-GQDCIMSGGTFL 100 Clostridium sp. CAG...
3FOZ_A   111 YFKALLe-gLs-PL-Ps--AD-------P---EVRAR---I----EQ----Qaaeq----gwesLHRQLQEVDPVAAARI 160 Escherichia coli K-12
Q6YQU8    99 YLKSAL---FdyELt----PKslflpptS-----------Lpai------------------enMIDFIKQKDPQLIANL 142 Onion yellows phyto...
B3R0E8    99 YIKSAL---FnyELs----NKkn----tS-----------IiyknDK----Kvydvd---dmefMIREIRQKDPKLV--F 147 Candidatus Phytopla...
EFC40682 125 YLNTFId-gTnlEI-P------------------QPTtlsV----QKmddlTrvstd---ewdrRYKVLQEKDPEYASKI 177 Naegleria gruberi
EGC28765 115 YLDSILkgsRepEL-Tq--KE-------------REEidiL----ES----Kikns----qwdyYYDILKEIDIESAKCI 166 Dictyostelium purpu...
Q556J1   114 YLDTILkgsRvdLT-Nd--KE-------------RDEiklY----YN----Kikqed---nwdyYYDLLKKYDIESANMI 166 Dictyostelium disco...
A0CSW7    96 FMNYLLn--------------------------sRKEqfeEnqikAAdleaSkllencrdpqalLKEHFKNYD-DS---I 145 Paramecium tetraurelia
CDA37368 101 YTKALL---FpyYFp----KE-------EntgPVIKEyppL----NE-----------------MLKTIKELDPDSLNLI 145 Clostridium sp. CAG...
CDE08488 103 YLKALLy-rY--EFhEv--P-------------KIEH---I----EDltl------------eeMLATLQREGVSL-ENV 144 Bacillus sp. CAG:988
CDE15418 101 YVRAAL---YpyEF-StvnDE-------I---D-------F----SNksd------------seLFDELQKVDPDSAKEL 143 Clostridium sp. CAG...
3FOZ_A   161 HPNDPQRLSRALEV--FFIS-G-K---TLT--------------ELT-Q----------TsgdalpyqvHQFAI--A--- 203 Escherichia coli K-12
Q6YQU8   143 DLKNPRRILSAYQD--LLEG-------TLR--------------SQKnKkhnsl----------yssliFYLDI------ 183 Onion yellows phyto...
B3R0E8   148 DKYNPRRVVSAYLD--LNSD-------KLR--------------SQKkYknnpi----------ydiltIYLDI------ 188 Candidatus Phytopla...
EFC40682 178 HRNDLYRLNRAYTI--VTES-G-K---TMK--------------EFKyKngfmdkvs----ennldvrgIVLYL------ 226 Naegleria gruberi
EGC28765 167 SRNNVKRLTMSLYFnlIKEV-------KFSslkdqfsdsikdsyDFRc---------------------FYLTT------ 212 Dictyostelium purpu...
Q556J1   167 LKNDFIRLSKSLYFntVKGV-------KFStqkddyqdsianeyDFRt---------------------FYLSG------ 212 Dictyostelium disco...
A0CSW7   146 NSSDRYRIQKALRF--ALLTkGeSitsPFN-----------------------------Qd-------dPRLCDemDirg 187 Paramecium tetraurelia
CDA37368 146 DTKNPRRVERAYDL---AKS-GnKredIESmysnlp---------------------------lypcifIRLKV------ 188 Clostridium sp. CAG...
CDE08488 145 DVSNRRRVERLYTN--V------------M--------------AGV-FptktgnellyDt--------VFIGL--Tt-- 183 Bacillus sp. CAG:988
CDE15418 144 HMNNRRRVEQALRI-------------YYSgqk---------ksDLKmKdisp------------iypvRIFGIemP--- 186 Clostridium sp. CAG...
3FOZ_A   204 -----PasRELLHQRIEQRFHQMLASGFEAEVRALF-----------ArgdlhtdlpS------IRCVGYRQ---MWS-- 256 Escherichia coli K-12
Q6YQU8   184 -----D--RQILKKRVILRLEQMLKQGFIEEVNQi---------------------qThfpnpnFNIIGYRE---IKA-- 230 Onion yellows phyto...
B3R0E8   189 -----D--KNILQARVIERLEKMFKMGFIEETKQi---------------------lQeypyanFNIIGYRE---IKL-- 235 Candidatus Phytopla...
EFC40682 227 -----D--RYKLYASLERRCENLVEAGLLEEVYSLM-----------DrgilldhtvP------FRSIGYKEaydFIN-- 280 Naegleria gruberi
EGC28765 213 -----E--RYKRTTMLNERCEAMVYSGLLDEVFHLLmtqen--finsK---------A------GKSLGYKE---TIK-- 263 Dictyostelium purpu...
Q556J1   213 -----D--RSKMHITLNNRCESMFKMGILEEVYDLLkrdkdlhfknsK---------S------SESIGYRQ---IMD-- 265 Dictyostelium disco...
A0CSW7   188 fffteP--QENISKKIYARCDEMIRQGVIEEFYQFY-----------Qm-------qHqkefrvTTPLGYDE---FVNll 244 Paramecium tetraurelia
CDA37368 189 -----D--KDQLRSKIKERVLIQVKDGLFEEEERLEk-------------------aNpefsstFRGIGFKE---IYQg- 238 Clostridium sp. CAG...
CDE08488 184 -----E--REHLYSIIDTRVSKMISDGLVDEVKSLL-----------PyandskalsT--------AIGYKE---IIS-- 232 Bacillus sp. CAG:988
CDE15418 187 --------VELGNSRINDRVDEMFKDGLIDEVKNFI-----------Ke--------GktnskaFAAIGYKE---VIE-- 234 Clostridium sp. CAG...
3FOZ_A   257 -----YL----------------Eg----------EI-S--Y---D-----E--------MVYRGVCATRQLAKRQITWL 286 Escherichia coli K-12
Q6YQU8   231 -----LL----------------Eg----------KI-T--L---D-----Q--------AKTLIIQKTMQYAKRQKTWF 260 Onion yellows phyto...
B3R0E8   236 -----FL----------------Ek----------KI-N--L---T-----E--------AKKLIISKTMNYAKKQKTWF 265 Candidatus Phytopla...
EFC40682 281 -----YM----------------KtvdrrdhffksaLkKsfL---------R--------FLREFKVSTRRYSKHQNTWF 322 Naegleria gruberi
EGC28765 264 -----LLlnqypnistnkinknkNknknn-kneisE--EsiV---N--------------YIKDFRSVTRQYSKRQDTWF 318 Dictyostelium purpu...
Q556J1   266 -----LLlkpvvrniddts-----inmnqslnaidE--SdvI---S--------------TILNFQTANRNYYRKQYSWF 316 Dictyostelium disco...
A0CSW7   245 kcfqsIL----------------Eg----------RYiS--NkraE-----KqkreyvlkFIQQFYIKSRQYAAYQRKYF 291 Paramecium tetraurelia
CDA37368 239 -----------------------------------K-----R---EgwtkeK--------IINQVMVDTIQYARRQRTFL 267 Clostridium sp. CAG...
CDE08488 233 -----YL----------------Eg----------DC-T--L---E-----E--------AISLIQKNSRHYAKRQYTFF 262 Bacillus sp. CAG:988
CDE15418 235 -----GL----------------En----------NE-T--E---K-----D--------ISDKIKLNTRRYAKRQRTFL 264 Clostridium sp. CAG...
3FOZ_A   287 RGW 289 Escherichia coli K-12
Q6YQU8   261 KNQ 263 Onion yellows phytoplasma OY-M
B3R0E8   266 KNQ 268 Candidatus Phytoplasma mali AT
EFC40682 323 RKD 325 Naegleria gruberi
EGC28765 319 KKD 321 Dictyostelium purpureum
Q556J1   317 KKE 319 Dictyostelium discoideum AX4
A0CSW7   292 RSN 294 Paramecium tetraurelia
CDA37368 268 RHQ 270 Clostridium sp. CAG:568
CDE08488 263 RHQ 265 Bacillus sp. CAG:988
CDE15418 265 RHQ 267 Clostridium sp. CAG:288
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