Conserved Protein Domain Family
ATPase_2

?
pfam01637: ATPase_2 
ATPase domain predominantly from Archaea
This family contain a conserved P-loop motif that is involved in binding ATP. There are eukaryote members as well as archaeal members in this family.
Statistics
?
PSSM-Id: 307662
View PSSM: pfam01637
Aligned: 28 rows
Threshold Bit Score: 142.854
Threshold Setting Gi: 2496210
Created: 15-Jul-2016
Updated: 4-Aug-2016
Structure
?
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2496254    3 FFNREKEINKILSIIEGEPNNIYFIYGSLNSGKSTLMREIVVNRLDISKy----IPFFIDFRTRNILNVDNfiec----- 73
gi 2496247    3 FYNREKELNYLKTYCQLDPNSILFVYGPKSSGKSTVMRRVIKELEDSNi-----VFFYYNLRKYATYSKEEflrv----- 72
gi 2496250   20 FYNREKELNYLKNYVQLEPNSILFVYGPKSSGKSTVMLRVIEELSKKDDl----VFFYYDLREYATPTKEEflei----- 90
gi 2496255    7 FFDREKEINYLVKVLSFEPNLIYFIYGPINSGKTTLIKHIIENKLDRDKy----VVFYINLREHFISKYEDfiev----- 77
gi 2496248    3 FFNREKEIEEILHIIESEPQRINFIFGSINSGKTALINEIINNRLNKDKy----VVFYFDLREIFISKYDDfiev----- 73
gi 2496243    3 FFDREKEIAEILHILNREPDDVYFIYGPINSGKTALINEIINNRLDKDKy----VVFYFDLREIFISKYDDfiev----- 73
gi 2496251    6 FFNRVEEIKEILSILEEEPNLIYFIYGPINSGKTALINEIINNRLDKNKy----VVFYIDLREIFISKYDEfeaklratk 81
gi 2496246   15 FFNREKEITEILSILEGNPDLVYFVYGPLNSGKTALISEIINNRIDKNKy----VVFYINLRGIFISKYKDfiev----- 85
gi 81553374  19 LFDRERELKDLEKLLET--YPIVVITGLRRVGKSSLVKVFLNKSDLLHItvdgrRLYETSGGNISSHHLTRflg------ 90
gi 2496210    2 FVDREEELKALNEKLDSNNFEFIVIYGRRRIGKTKLALKSVENRe---------HIYYLAVEGDNLKHFKRy-------- 64
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2496254   74 ----------lfevDEKSEIDDFReyaksladllvk---gseeiskyylgmPIKIPKPFFdkifn-kkdksADVYQYIEY 139
gi 2496247   73 ----------ffekSEKKYLLNKLe-------------------------lNLGVFKFGVeenfdfnnlklNDVFAKINE 117
gi 2496250   91 ----------ffekGDKKYLLNRFe-------------------------iNLKIFKFGIeekfdfdniklNDVFSKMKE 135
gi 2496255   78 ----------lfntYEETFIEKLKkyllsfindlp-----knidvkstiltGIPVPKNTLnefls--tknsENVFEYLTK 140
gi 2496248   74 ----------lfeeYEEPFIDKVKrlflslikdypdviksyallnitgvvdSIPIPKNTLnellk--krnvKNVFRYITS 141
gi 2496243   74 ----------lfeeYEGN--KKPVeiiksli-------------kdvpslcGIPAPKNTLeeilk--kkttKNVFRYITK 126
gi 2496251   82 tfgfrliievlfeeYEDD--KKPIeiirsli-------------kdapslcGIPTPKNTLeeilk--kkttKNVFKYITN 144
gi 2496246   86 ----------lfeeYEED--RKPVeiiksli-------------kdvpslcGIPTPKNTLeeilk--kkttKNVFKYITN 138
gi 81553374  91 ------------eeLSRISKSQKL---------------------------LNVLKRVRGitvsgtsielnPK-EFSLSD 130
gi 2496210   65 ----------------ASKVEPTI-----------------------------------------------EYAKEDWEA 81
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 2496254  140 LFAKLNEKGKK----PILIFDELQMIKeiTl----nGNRKLLWSLFQFLVALTKVQHLCHVFCLSSDSLFIEyvyk---t 208
gi 2496247  118 SINAVVEDGKK----PVLIIDELQKLKniYf----nGGKSLLNELFNLFVSLTKMEHLCHVICLTSDTLFIEeiyq---s 186
gi 2496250  136 SINAVIKDGKK----PILIIDELQKLKsiYfngegkGDKSLLNELFNLFVHLTKVRHLCHVICLTSDTLFIEeiyr---n 208
gi 2496255  141 IFEDIKKKGKQ----PILIIDELQKIGdlKi------nGFLIYELFNFFIDLTKEKHLCHVLCLSSDSLFIErvyn---e 207
gi 2496248  142 VLIKIKREGKQ----PIIIIDELQKIGdlKl------nGFLIYELFNYFVSLTKHKHLCHVFCLSSDSLFIErvyn---e 208
gi 2496243  127 VLMDIKKEGKQ----PILIIDELQKIGdmKi------nGFLIYELFNYFVSLTKHKHLCHVFCLSSDSLFIErvyn---e 193
gi 2496251  145 ILMDIKREGKQ----PIIIIDELQKIGdmKi------nGFLIYELFNYFVSLTKHKHLCHVFCLSSDSLFIErvyn---e 211
gi 2496246  139 VLMDIKKEGKQ----PIIIIDELQKIGdmKi------nGFLIYELFNYFVDLTKELHLCHVFCLSSDSLFIEqvys---e 205
gi 81553374 131 LLEKLNETAKRrkkkIVIFFDEAQYLRyyGs----rGGNDLLALFAYCYDN---FENVRFIISGSEVGVLHDflkledys 203
gi 2496210   82 YFNFLKDK--------IIIIDEFPNLIk--------ENPNVLSLFQRIVDIHLKNTKTKLIILGSSISMMGEkvls--yk 143
                       250       260       270       280       290
                ....*....|....*....|....*....|....*....|....*....|....*....
gi 2496254  209 geLEGRADY-ILVDDFdkqtaLKFIDFLAKEIlnKKLpkdEKELIYSYVGGKPVLIIKV 266
gi 2496247  187 stLENTSKY-YLIDWLrkgtiRNILKE-------EGFseeEINYCLDYL-SLPYEIVDL 236
gi 2496250  209 stLENTSEY-YLIDWLrkesiRNILKE-------EGFseeEVDYCLKYL-SLPYEISQL 258
gi 2496255  208 gtLKDRCKY-YLVDDFdykttKAFLKK-------HNFndeEIDIVWHYFGGKPIKLVEA 258
gi 2496248  209 amLEGRCKY-ILVDDFdretaLKFMDFLAKEn-nINLtneDKELIYNYVGGKPIDIIYV 265
gi 2496243  194 amLDGRAKY-LLVDDFdketaLKFMDFLAKEn-nISLtneDKELIYNYVGGKPKDIKYV 250
gi 2496251  212 amLKERVDY-ILVDDFdketaLKFIDFLSEEIlnKKLsdeDKELIYSYVGGKPILIINV 269
gi 2496246  206 amLKDRVDY-ILVDDFdketaLKFMDFLAEEIlnKKLsddEKELIYSYVGGKPILIIKV 263
gi 81553374 204 spLHGRGIGfLTVRPFtfdqsVDFLMEGFREVgek--infDVEEIVREIDGIVGYLVLF 260
gi 2496210  144 spLYGRKTGvLKIKPLkfkhlKEFFPKAiw---------eELVEIYGFADGIPYYLEKV 193
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap