4KZX


Conserved Protein Domain Family
Ribosomal_S27

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pfam01599: Ribosomal_S27 
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Ribosomal protein S27a
This family of ribosomal proteins consists mainly of the 40S ribosomal protein S27a which is synthesized as a C-terminal extension of ubiquitin (CEP). The S27a domain compromises the C-terminal half of the protein. The synthesis of ribosomal proteins as extensions of ubiquitin promotes their incorporation into nascent ribosomes by a transient metabolic stabilisation and is required for efficient ribosome biogenesis. The ribosomal extension protein S27a contains a basic region that is proposed to form a zinc finger; its fusion gene is proposed as a mechanism to maintain a fixed ratio between ubiquitin necessary for degrading proteins and ribosomes a source of proteins.
Statistics
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Aligned: 74 rows
Threshold Bit Score: 40.263
Threshold Setting Gi: 383796239
Created: 24-Apr-2019
Updated: 18-Jul-2019
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
4KZX_f               102 VLKYYKVDE-NGKISRLRRECPSdeCGAGVFMASHFD---RHYCGKCCLT 147 rabbit
A0B8S9                 3 VHKYYQLSG--ETIKARKPICPR--CGNGVFLAEHED---RMSCGRCGYT 45  Methanothrix thermoacetophila PT
bsuwp:MCON_3182       14 VSKYYELGG--DTIKSRKSVCPR--CGNGVFLADHGD---RQSCGKCGYT 56  Methanothrix soehngenii GP6
CBRAS:FFONT_1334       4 VHNYYEYDYkTKTIKLKNKRCPR--C--GSIMGHYKEpteRWYCGSCGYT 49  Fervidicoccus fontis Kam940
jgi:Mfer_0438          3 KYKLYEIKG--DKIIRKNPFCPR--CSSGVFMADHGD---RYACGKCGYT 45  Methanothermus fervidus DSM 2088
NZAGRC:Abm4_0721       3 VSSLYEVKD--DKLERKNPVCPR--CGGGVFMADHGD---RYACGKCGYT 45  Methanobrevibacter sp. AbM4
jgi:MSWAN_1764         3 KYELYEVKD--NKLVRKNPECVR--CSHGVFMADHGD---RYACGKCGYT 45  Methanobacterium paludis
jgi:Ferp_2229         14 VSRFYEIKG--DRVVRTRKFCPR--CGEGVFMAEHKD---RRTCGKCGYT 56  Ferroglobus placidus DSM 10642
goetting:Ngar_c26980  14 IYKFYKVSG--DKVTRSRRDCPR--CGKGTFMAEHKD---RFTCGKCGFT 56  Candidatus Nitrososphaera gargensis G...
A9A217                11 VYAYFKVDG--DKVSRIKKVCSR--CGKGTYMSEHKD---RNTCGKCGLT 53  Nitrosopumilus maritimus SCM1
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