2NZH,1PYB,3ERS,3PCO,4R1J,1E7Z


Conserved Protein Domain Family
tRNA_bind

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pfam01588: tRNA_bind 
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Putative tRNA binding domain
This domain is found in prokaryotic methionyl-tRNA synthetases, prokaryotic phenylalanyl tRNA synthetases the yeast GU4 nucleic-binding protein (G4p1 or p42, ARC1), human tyrosyl-tRNA synthetase, and endothelial-monocyte activating polypeptide II. G4p1 binds specifically to tRNA form a complex with methionyl-tRNA synthetases. In human tyrosyl-tRNA synthetase this domain may direct tRNA to the active site of the enzyme. This domain may perform a common function in tRNA aminoacylation.
Statistics
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PSSM-Id: 279869
View PSSM: pfam01588
Aligned: 38 rows
Threshold Bit Score: 77.6676
Threshold Setting Gi: 74509587
Created: 15-Jul-2016
Updated: 4-Aug-2016
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2NZH_B       15 IRTGTIVKAEEFPEARVpAIKLVIDFGTEIgiKQSSAQITKRYKpeg-linKQVIAVV-NFPPR-------RIAGFKSEV 85
gi 6226174   45 FEVAYIRNIKPHPSADK-LKLCDVETKNGI--LQIVCGASNVRAdikvvlaNIGIEIP-KGNLKik---esVIRGQKSYG 117
gi 12644560  45 VVFGKVVEVKEHPTKKK-LAVVKVQVQEHIf-IDVVTVDKSVREg-----dGVIVALP-NAKVGnmcvterEFDGVVSKG 116
gi 12230006  45 IITARVIERFDHPASEK-LIVCKVDTGKRI--YTVITADKTVNEgdyvilaLEGATLN-NGLKIep----rEFKGVISEG 116
3PCO_D       45 VVVGEVVECAQHPNADK-LRVTKVNVGGDRl-LDIVCGAPNCRQglrvavaTIGAVLPgDFKIKa-----aKLRGEPSEG 117
gi 3123292   46 VVIGHVLEREQHPNADK-LNKCLVDIGAEAp-VQIICGAPNVDKgqkvavaTVGAVLPgNFKIKk-----aKLRGEESNG 118
gi 93141320  45 VVVGRVLEREQHPNADR-LSVCQVEIGQAEp-VTIVCGASNVRAdiwvavaTLGSYLP-CIDLKlk---ptKLRGVRSEG 118
gi 2500989   45 VVLGRVISREKHPNADK-LSVCVVDIGTEEp-STIVCGAANVRAdilvpvaTLGSYLP-KVDLKik---paKLRGVKSSG 118
gi 81637622  96 FVVGYVESKEKHPNADK-LSVCKVNVGEET--LQIVCGAPNVDQgqkvvvaKVGAVMP-SGLVIkd----aELRGVPSSG 167
gi 2500986   44 VVVGKILEKAPHKNAEK-LSVCQVDVGKEV--LQIVCGAKNVAPnqfvpvaLNGALIG-STTIAk-----tELRGVESHG 114
                        90       100       110
                ....*....|....*....|....*....|.
2NZH_B       86 LVLGGIp-----GQGDVVLLQPDQPVPNGTK 111
gi 6226174  118 MLCSEEel--llSSNSDGIIELPKDAVVGDN 146
gi 12644560 117 LLLSAQel--glEEKSEGVLKIHEDFKPGTD 145
gi 12230006 117 MLCSLEel--glEEKSDRVYRFPDPVELGVN 145
3PCO_D      118 MLCSFSel--giSDDHSGIIELPADAPIGTD 146
gi 3123292  119 MICSLQe----lGIESKLVAKEYAEGIFVFP 145
gi 93141320 119 MICSLSelgltkESEGIHIFPEDAGLQAGQP 149
gi 2500989  119 MICSLAelg-lsKESEGIHIFPDLDLPSGSP 148
gi 81637622 168 MICSAKeldlpdAPAEKGILVLEGDYEAGDA 198
gi 2500986  115 MICSSIel--gfPKINDGILELDESvgelvl 143
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