1U0R


Conserved Protein Domain Family
NAD_kinase

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pfam01513: NAD_kinase 
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ATP-NAD kinase
Members of this family include ATP-NAD kinases EC:2.7.1.23, which catalyzes the phosphorylation of NAD to NADP utilising ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus. Also includes NADH kinases EC:2.7.1.86.
Statistics
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Aligned: 18 rows
Threshold Bit Score: 179.483
Threshold Setting Gi: 124028542
Created: 24-Apr-2019
Updated: 18-Jul-2019
Structure
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Program:
Drawing:
Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
1U0R_A     7 VLLVVHTGr--------------------DEATETARRVEKVLGDNk-----iALRVLSAEAVDRGSLHLAPDDMRAMGV 61  Mycobacterium tuber...
P74430     4 VGIIFNDDk--------------------PTACSVAQELQEQLQQS-------GFTVAMETGSGGLLGYSQPDRPICHT- 55  Synechocystis sp. P...
Q8U1V2     3 FGIVARRDk--------------------EEALKLAYRVYDFLKVS-------GYDVVVDKDTYEHFPY----------- 44  Pyrococcus furiosus...
Q58327   304 FGIVVREDk--------------------EEAINLAIEICKYLKDK-------NIPFCVEDFL----------------- 339 Methanocaldococcus ...
O26958     4 IGIIARFDv--------------------AEAVEIAERVASFLLNR-------GVEITVDLKLTEELP------------ 44  Methanothermobacter...
GAA58009   8 IGIVGHPRh--------------------PTALTTHEMLYRWLCTK-------GYEVIVEQQIAHELQLK---------- 50  Clonorchis sinensis
P27748    15 VGIIANPIsardirr-------vianansLQLADRVNIVLRLLAALascgverVLMMPDREGLRVMLARHLARRQGPDSG 87  Cupriavidus necator...
Q9HRC1     4 VGVVVNPIagmggrvglkgtdgnvaearkRGADQRAPQRARTALDAlrdaagdVSVVTYDEPMGGGVAAAAGFTPTVVGH 83  Halobacterium salin...
Q9HJA2     9 VAFFVNPLagygsffnlkgsdglkiedpeKSISIRRSMEFLRLVDFs-----rYFFIVPSGYMGEREVSAFTSRYSVIYQ 83  Thermoplasma acidop...
Q971Y1     5 IGFLVNPIagsggrighkg-----sddlyienleTPLKIKRFLSLApk---kgVEYIVAENKMGEIYFNN-DFKFTVIET 75  Sulfurisphaera toko...
1U0R_A    62 E---------------IEVVDADQHAADGCELVLVLGGDGTFLRAAELARNa--SIPVLGVNLGRIGFLAEA--EAEAID 122 Mycobacterium tuber...
P74430    56 ----------------RIEHLTPPHFDESMPFAIVLGGDGTVLSAFRQLAPl--GIPLLTINTGHMGFLTEI--YLNQLP 115 Synechocystis sp. P...
Q8U1V2    45 ----------------FNERDVIPLEEFDVDFIIAIGGDGTILRIEHMTKK---DIPILSVNMGTLGFLTEV--EPSDTF 103 Pyrococcus furiosus...
Q58327   340 ----------------RERVGGDKFDISAISHIIAIGGDGTILRASRLVNGe--TIPIIAVNMGKVGFLAEF--CKDEVF 399 Methanocaldococcus ...
O26958    45 ----------------QLREYGEDIRNMDADMILTIGGDGTILRTRSLIEDk--EIPILGINMGTVGFLTEV--DPENVF 104 Methanothermobacter...
GAA58009  51 ----------------NVKTGTLAEIGQLADLAVVVGGDGNMLGAARTLARy--DIKVIGINRGNLGFLTDL--DPDNAQ 110 Clonorchis sinensis
P27748    88 LpavdyldmpvtarvdDTLRAARCMADAGVAAIIVLGGDGTHRAVVRECG----AVPIAGLSTGTNNAYPEM--REPTII 161 Cupriavidus necator...
Q9HRC1    84 Pttpa-------staaDTRAAVEAFIDHGVDVILFVGGDGTATDVATAVTAhdaSVPVLGVPAGVKVYSAVFavQPAAAG 156 Halobacterium salin...
Q9HJA2    84 Ahwps--------trdDTLGFLRNV--GDADILVFAGGDGTARDILSAGV----RIPVIGVPAGVKMYSSVFaiSPSHAA 149 Thermoplasma acidop...
Q971Y1    76 Lnkek-------ttreDTIYVTNRFLELKCDIIVFAGGDGTARDIYSVVDQ---KIPILGIPSGVKMHSGVFanTPEAAA 145 Sulfurisphaera toko...
1U0R_A   123 AVLEHVVA-QDYRVEDRL----TLD---------------------------VVVRQGGR---------------IVNRG 155 Mycobacterium tuber...
P74430   116 TAIEQLIN-GDYQIESRS----MMT---------------------------VRLMREEN---------------LLWEA 148 Synechocystis sp. P...
Q8U1V2   104 FALSRLIE-GEYYIDERI----KVR---------------------------TYINGENR------------------VP 133 Pyrococcus furiosus...
Q58327   400 EIIDKVIY-GEYEIEKRS----KLS---------------------------CKIIKDNR---------------VIKTP 432 Methanocaldococcus ...
O26958   105 SALEAVLR-GEYAVEKRT----LLS-----------------------------VYHNDE------------------LP 132 Methanothermobacter...
GAA58009 111 QQLADVLE-GHYISEKRF----LLE---------------------------AQVCQQDC---------------QKRIS 143 Clonorchis sinensis
P27748   162 GLATGLYAtGRIPPAQALasnkRLD---------------------------IVIRDGNGgfr----------rdIALVD 204 Cupriavidus necator...
Q9HRC1   157 RVAATFED-----TTTRE----VSDidegayrdgevqttlrgvvatpvtegaDALQPAKQayagttgalaagvadSV--- 224 Halobacterium salin...
Q9HJA2   150 QSLNAISK-PDIRTADAE----VMDideelyrrgvlsa--rsygylkvpilnDIVMNSKAeydmgg---vediaeYIIDH 219 Thermoplasma acidop...
Q971Y1   146 IILTKYVN-GEATLTDAE----ILDvdeeeyrkgryev--klygiaktvtfgNYLTPSKEeiisnee-eleaiaeYVINN 217 Sulfurisphaera toko...
1U0R_A   156 WaLNEVSLEKGPRLGVLG--VVVEIDGRPVSAFGCDGV-----------------------------LVSTPTGSTAYAF 204 Mycobacterium tuber...
P74430   149 LsLNEMVLHREPLTSMCH--FEIQVGYHASVDIAADGI-----------------------------IVSTPTGSTAYSL 197 Synechocystis sp. P...
Q8U1V2   134 DaLNEVAILTGIPGKIIH--LKYYVDGGLADEVRADGL-----------------------------VVSTPTGSTGYAM 182 Pyrococcus furiosus...
Q58327   433 SaLNEMVVITKNPAKILE--FDVYVNDTLVENVRADGI-----------------------------IVSTPTGSTAYSL 481 Methanocaldococcus ...
O26958   133 SaLNEVVLMTRRPAKMLH--IEISVDDEVVEELRADGI-----------------------------IIATPSGSTAYSM 181 Methanothermobacter...
GAA58009 144 TaINEVVLHPGKVAHMIE--FEVYIDEIFAFSQRSDGL-----------------------------IISTPTGSTAYSL 192 Clonorchis sinensis
P27748   205 AvISHEHFIGARALWKTDtlAAVYVSFADPEAIGLSSIagllepvgrreegglaielaapgegefdlCAPIAPGLMCTVP 284 Cupriavidus necator...
Q9HRC1   225 --RDGVTYVLGPGGTLAEiaDALGVSGSPLGVDVYRDGalvvrdgsase--------itaalgtdnvVYVSPIGGQGFVF 294 Halobacterium salin...
Q9HJA2   220 --MDDRYYVIGPGNTCKTieTEMGINTNPLAFDIIRNRklikedaaeqd--------iydacrkgcrLIISPIGGQNFLI 289 Thermoplasma acidop...
Q971Y1   218 LiRDNEYYIFGSGSTVKYilKKLGYKTNFLAIDVTYGKklvktsvnyy---------dllnltgelnLILTPIGKQGFLI 288 Sulfurisphaera toko...
1U0R_A   205 SAGGPVLWPDLEAilvvpnnaHALFGRPMVTSPEATIAIEieadGHDALVFCDGRREMLIPAGSRLEVTRCVTSVKWARL 284 Mycobacterium tuber...
P74430   198 SAGGPVVTPDVPVfqlapicpHSLASRALVFSDLEPVTIFpa-tPNRMVLVVDGNGGCYVLPEDRVHLSKSPYPAKFIRL 276 Synechocystis sp. P...
Q8U1V2   183 SAGGPFVDPRLDVilvvpllpLPKTSVPMVIPGSSRVDITlv-sDREIILAIDGQYYEYLPPDVEITVVKSPRKTKFVRF 261 Pyrococcus furiosus...
Q58327   482 SAGGPIVEPNVDCfiispicpFKLSSRPLVISASNRIKLKlk-lEKPALLVIDGSVEYEINKDDELIFEKSDSYAYFVKG 560 Methanocaldococcus ...
O26958   182 SAGGPIVDPRVEAflivpicpFKLSARPLVVSNKSVIRVKllrkGKKAIAVIDGQYEEEINHMDEVIFRKSERKAHFVRL 261 Methanothermobacter...
GAA58009 193 SAGGPILTPSLDAitlvpmfpHTLSARPLVINSSSTIRLRfshrRNDLEISCDSQIALPIQEGEDVLIRRCDYHLNLIHp 272 Clonorchis sinensis
P27748   285 VAGWQRLEHGRPH------------------------RVR----QRSGIVALDGERELAFGPDDEVTVTLHDHAFRSIDV 336 Cupriavidus necator...
Q9HRC1   295 GRGNDQISPAIID-----------RSEVRVVASPQKLD------QTGVLRVDTGSEDTDASLRGWQRVRTGRFEKRLVNV 357 Halobacterium salin...
Q9HJA2   290 GRGNKQISSRVLE--------LLDAEDIIVVASPS---------KAETIRALYVDSDVNPWKNGYVRVLSGYGKYKIVPV 352 Thermoplasma acidop...
Q971Y1   289 GRGNQEIGPEVLQ--------KIRRDKIIIVSTRSKLN------TIECLRIDTGNPLLDRKFQGIYKVIVGYEEFVAIKT 354 Sulfurisphaera toko...
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