3DI2


Conserved Protein Domain Family
IL7

?
pfam01415: IL7 
Click on image for an interactive view with Cn3D
Interleukin 7/9 family
IL-7 is a cytokine that acts as a growth factor for early lymphoid cells of both B- and T-cell lineages. IL-9 is a multi-functional cytokine that, although originally described as a T-cell growth factor, its function in T-cell response remains unclear.
Statistics
?
Aligned: 19 rows
Threshold Bit Score: 95.1847
Threshold Setting Gi: 612005168
Created: 24-Apr-2019
Updated: 18-Jul-2019
Structure
?
Program:
Drawing:
Aligned Rows:
Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
3DI2_A        13 QYESVLMVS--IDQ-LlDSMKEIgSNCLNNEFNFF-KRHICDAnKEGMFlfraARKLRQFLKMNSTGDFDLHLLKVSE-G 87  human
XP_008253910  37 EYENVLMIS--INE-L-DKMIEIgSNCLNNESNFF-KKHSCDDnKEADFleraARKLDQFHDMSINEDFQNHLERVSKgT 111 rabbit
P26895        36 AYQNVLMVN--IDD-L-DNMINFdSNCLNNEPNFF-KKHSCDDnKEASFlnraSRKLRQFLKMNISDDFKLHLSTVSQgT 110 cattle
XP_003269515  36 QYESVLMVS--IDQlL-DSMKEIgSNCLNNEFNFF-KRHICDAnKEGMFlfraARKLRQFLKMNSTGDFDLHLLKVSEgT 111 northern white-...
P10168        36 AYESVLMIS--IDE-L-DKMTGTdSNCPNNEPNFF-RKHVCDDtKEAAFlnraARKLKQFLKMNISEEFNVHLLTVSQgT 110 house mouse
XP_003782221  23 THMGILDINflINK-L-QTDLSSkCSCSSNVTSCLcLPIPSDNcTRPCF----QEGLSQMTNSTVHTEHPQIFNRVKK-T 95  small-eared galago
P15248        23 TLAGILDINflINK-M-QEDPASkCHCSANVTSCLcLGIPSDNcTRPCF----SERLSQMTNTTMQTRYPLIFSRVKK-S 95  human
ELV11413      23 TSEGIWNLNslIQK-W-QEEPSAkCNCSANVTSCLcLPIPSDNcTTPCF----QEGLAQMTHVMANTASSLIFYKVKR-T 95  Chinese tree shrew
NP_001041603  36 EYQHVLMIS--IND-L-DIMIKNrTNCSNNEPNIL-KKHACDDnKEGMFlyraAHKLKQFVKVNNSEDFNLHLSRVSQgT 110 dog
XP_023607687  36 EYQHVIMVS--LND-L-DRIRENdSNCLNNEPNFF-KKHSCDDdKEATFlktaARKLKQFLKMNIHEEFKLHLSIVSQgT 110 little brown bat
3DI2_A        88 TTILlnctgqvkgrkpaalgaaqptkslEE-----------------------NKSLKEQKKlNDLCFLKRLLQEIKTCW 144 human
XP_008253910 112 LTLV------------------------NCtgk------------------eeKKPLKDQKK-NGRCFLKKLLQKIKTCW 148 rabbit
P26895       111 LTLL------------------------NCtskgkgrkppslseaqptknleeNKSSKEQKKqNDLCFLKILLQKIKTCW 166 cattle
XP_003269515 112 TILL------------------------NCtgqvkgrkpaalgeaqptksleeNKSLKEQKKlNDLCFLKRLLQEIKTCW 167 northern white-...
P10168       111 QTLV------------------------NCts-------------------keEKNVKEQKK-NDACFLKRLLREIKTCW 146 house mouse
XP_003782221  96 VAALknnk----------------cpffSC-----------------------EQPCNQTTAgNTLTFLQSLLEIFQKEN 136 small-eared galago
P15248        96 VEVLknnk----------------cpyfSC-----------------------EQPCNQTTAgNALTFLKSLLEIFQKEK 136 human
ELV11413      96 VQGLknnk----------------cpffSC-----------------------EQPCNQTTAgNMLTFLKSLLEVFQKEN 136 Chinese tree shrew
NP_001041603 111 LQLL------------------------NCtpk------------------edNKSLKEQRKqKSLCSLGILLQKIKTCW 148 dog
XP_023607687 111 LKLL------------------------NCtrkdkekkqpslgevqptknleeKKSSKGQKKqDEMCFLMILLEKIKTCW 166 little brown bat
3DI2_A       145 NKILM 149 human
XP_008253910 149 NKILR 153 rabbit
P26895       167 NKILR 171 cattle
XP_003269515 168 NKILM 172 northern white-cheeked gibbon
P10168       147 NKILK 151 house mouse
XP_003782221 137 MRQMM 141 small-eared galago
P15248       137 MRGMR 141 human
ELV11413     137 VRKMR 141 Chinese tree shrew
NP_001041603 149 NKILR 153 dog
XP_023607687 167 NKILS 171 little brown bat
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap