2OWA,2OLM,3MDB


Conserved Protein Domain Family
ArfGap

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pfam01412: ArfGap 
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Putative GTPase activating protein for Arf
Putative zinc fingers with GTPase activating proteins (GAPs) towards the small GTPase, Arf. The GAP of ARD1 stimulates GTPase hydrolysis for ARD1 but not ARFs.
Statistics
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PSSM-Id: 307528
View PSSM: pfam01412
Aligned: 126 rows
Threshold Bit Score: 104.249
Threshold Setting Gi: 121961702
Created: 15-Jul-2016
Updated: 4-Aug-2016
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
2OWA_B         24 DNFFQIVRN--R-PENRTCFDC---ESRNP-TWLSLS-FAVFICLNCSSDHRKMGVHISFVRSSDLDKFTPIQLVRMDIg 95
gi 74851131    10 YGLLRSLFQ--D-PNNQCCAEC---NSANV-PYVCIK-LGVFICPTCAHFLSTLG---FKVRPIMGSSFSEEDISRLQSi 78
gi 75014053     5 DTILWRLRE--L-EENSKCADC---TDSFP-RYMNTT-YGTFVCSVCGAIHRELG---NRVKSISSDKFTQQDIERLEKv 73
gi 75030764    12 KEVLRKLSQ--N-GGNKNCFDC---GMRGP-LYVVSD-FGILVCSGCSAVHRSFQ---HKVKGITMSEFTDDEIARFSVs 80
gi 122023343   62 RDEVRKLSQ--K-CGNRFCIDC---GIRGP-LYVVTN-FRVFVCSTCAALHRSLQ---HKVKGISMTEFTDEEVACLNVg 130
gi 122077827    5 RDEVRKLSQ--K-DGNRFCMNC---RMRGP-VYVVLD-FGTFVCSACASLHRNKQ---HKVKGITMTEFTDEEVARLKVc 73
gi 122020242  247 QSPLYALCIadR-PSNQICADC---GEKWP-TWAVLGpFGCFVCIHCVGVHRQLRPHCC--REVQLDNWDAAEIDFMAKr 319
gi 145344977    6 EQALTALAR--E-PGNKTCFSCvgpGSLAP-RSVCVP-FGIFVCTRCSGIFRDFN---FRIKSISASTFSGDEVEMLRRk 77
gi 126649149   11 IERLRSFQK--ScIENRKCANC---NEIGP-NYVCIN-FGTFVCSVCSGIHREFN---HKVKGISLSKWKFDEIRLICSl 80
gi 159111158   10 KNAIDALRR--K-PENKQCADC----KSLSvPYINLT-CGTFVCARCAGIHREFD---HRVKSVSNSVFKLDEIQALG-- 76
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|...
2OWA_B         96 GNGRARNYFKQVl-----------gVNFSPKTKEYASSIcGRQYKQILDSEIS 137
gi 74851131    79 GNLVSKQFWLARwtpmd----ivmpP---PEDPNLESFL-RLKYIEKRWTSSL 123
gi 75014053    74 GNKMADEIWLSKwsqqq----yplpFP--SDEKRVRDFI-KMKYIEKKWIKEG 119
gi 75030764    81 GNDRARKVWLSTfhd-------qlpRS--GNVMALKDHV-HVVFEERRFWSAQ 123
gi 122023343  131 GNDRAARVWLASyen-------nkpPH--GSDIAVRDFI-VNAFENMAYVNRE 173
gi 122077827   74 GNDRAESVWLHGfkg-------erpPV--GNDFALQQFF-SRVYVAKEFASSA 116
gi 122020242  320 GNDVVNDELEYAgfflgsgdavykpVGSSSRREVREEYI-TLKYEGTF-TRER 370
gi 145344977   78 GNEAARRTFLARwnp-------aepLPQSGNTVRGKVWI-KAVFVDKLYYDDA 122
gi 126649149   81 GNKKDFLTFLGNrdfn-----slgpPPNSNNHLILKEFI-RNKYINRIWINQS 127
gi 159111158   77 GNDLDKRTYLPYwseqv----fklpEPGSEDNGRVRDFI-RMKYVEKRFCHEQ 124
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