4DPG,1KRS,1EQR,3E9H,1EFW,2XGT,3NEL,1X54,1WYD,5FKU,5GRO,4H02,4AH6,3DM3,1ASY,1YNX,3AMU,4J15


Conserved Protein Domain Family
tRNA_anti-codon

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pfam01336: tRNA_anti-codon 
Click on image for an interactive view with Cn3D
OB-fold nucleic acid binding domain
This family contains OB-fold domains that bind to nucleic acids. The family includes the anti-codon binding domain of lysyl, aspartyl, and asparaginyl -tRNA synthetases (see pfam00152). Aminoacyl-tRNA synthetases catalyze the addition of an amino acid to the appropriate tRNA molecule EC:6.1.1.-. This family also includes part of RecG helicase involved in DNA repair. Replication factor A is a hetero-trimeric complex, that contains a subunit in this family. This domain is also found at the C-terminus of bacterial DNA polymerase III alpha chain.
Statistics
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PSSM-Id: 334496
View PSSM: pfam01336
Aligned: 575 rows
Threshold Bit Score: 29.8924
Threshold Setting Gi: 74543544
Created: 18-Mar-2017
Updated: 23-May-2017
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
4DPG_A   59 KVAGRIHAKR----ASG-GKLIFYDLRGEG-VKLQVMANSrnykseEEFIHINNKLRRGDIIGVQGNPGKT-KKGe-LSI 130  human
Q95Y97   70 LTVGIVKDI-----SQD-GTTYTYDLCDPNnTEMEYRTLKyd---nEGSTFDHSSIVEGTRVRAIGKLKGF-DGN--NTI 137  Caenorhabditis elegans
Q98E34  980 SVAGLVLVRQ----RPGkGNAIFLTLEDDK-AVANVIFWE------RTFTRFRPIVMGARFVKVSGKLQSE-SGV--IHI 1045 Mesorhizobium loti ...
Q828V6 1008 LVAGAKAATQtppvRSG-KRVIFTTLDDGT-GLVDLAFFD------DSHDACAHTVFHSWLLLVRGVVQRRgPRS--LSV 1077 Streptomyces avermi...
Q83C00  979 VVAGMMMGMRtittRSG-KRMAILSLEDQT-GKIDVTLFN------DLYQQVAADLTDHAILVIRGTVGRDdYTGg-QKM 1049 Coxiella burnetii
O27456  140 SIIGMVNDVR----NTK-NNHRIIELEDDT-GEISVVVHNe----nHKLFEKSEKIVRDEVVGVHGTKKGR------F-V 202  Methanothermobacter...
Q9HMR7  167 AIVGMVNDIR----STT-SGHWRVELEDTN-GVFPVLVLKd-----RDVSDLVDDLLLDEVIAVSGTLADD---G--TIL 230  Halobacterium salin...
Q9HLK5  145 KVVGMVSEVS----MTK-NGHKRIVIEDLD-DSITAIVMK-------DRGPVNEIILEDEVIGIIGSVSQS-SKD--PVI 208  Thermoplasma acidop...
Q7NHH2    6 TLEGEVTAYLp---GKR-GLVNRCTLATPE-GEIVVKFPK------EWAYRVTQTIVVGERVQVRGKLKFD-DDGe-TYL 72   Gloeobacter violaceus
Q8DHM7   12 CLEGTVEEIF----YKK-GRPKVVILKTPT-GRVWIKLEK------SLRRELAQVPKVGDRLRLEGTVKEK-YDGwvKQY 78   Synechococcus elong...
4DPG_A  131 IPYEITLL 138  human
Q95Y97  138 MLFNITPV 145  Caenorhabditis elegans
Q98E34 1046 VAEKIEDL 1053 Mesorhizobium loti MAFF303099
Q828V6 1078 VGAAAWNL 1085 Streptomyces avermitilis
Q83C00 1050 VADMLLTL 1057 Coxiella burnetii
O27456  203 VASEIFHP 210  Methanothermobacter thermautotrophicus str. Delta H
Q9HMR7  231 FADDIYFP 238  Halobacterium salinarum NRC-1
Q9HLK5  209 FVNEIIRP 216  Thermoplasma acidophilum DSM 1728
Q7NHH2   73 KATVLLHL 80   Gloeobacter violaceus
Q8DHM7   79 QASHLEFL 86   Synechococcus elongatus
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