3SM8,3VQR,1Y56,4PAB,5I39,4WCT,3DJE,1ZOV,3BHF,2UZZ,3IF9,6PXS,3AWI,3PVC,1DDO,3DME,4X9N,2R4J,3DA1


Conserved Protein Domain Family
DAO

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pfam01266: DAO 
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FAD dependent oxidoreductase
This family includes various FAD dependent oxidoreductases: Glycerol-3-phosphate dehydrogenase EC:1.1.99.5, Sarcosine oxidase beta subunit EC:1.5.3.1, D-alanine oxidase EC:1.4.99.1, D-aspartate oxidase EC:1.4.3.1.
Statistics
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Aligned: 521 rows
Threshold Bit Score: 33.14
Threshold Setting Gi: 74576847
Created: 22-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
3SM8_A        11 DYLVIG-AGIAGASTGYWLs-AH---G----RVVVLEREaQ------PG--Y-HSTGRSAAHYTVA-YGTPQ------VR 65  Pseudomonas aer...
EWG51937       5 SYLIVG-AGVFGVSTAYQLiqKYpnaS-----VTIVDRDpY------DGdnRvAASWDWNKVVRADy-DDLLy------- 64  Fusarium vertic...
Q9UTM9         4 TIVIVG-CGVFGLSTAVELa-KNhs----fdNIIAIDAEpV------PS--SmSAANDINKIVRPe-YADLKy----mK- 63  Schizosaccharom...
4WCT_B        27 SIIVIG-AGTWGCSTALHLa-RR---Gy--kDVTVLDPHpV------PS--PiAAGNDINKIMEHSeLKDGSsdprsaAF 91  Aspergillus fum...
3DJE_A         8 SLLIVG-AGTWGTSTALHLa-RR---Gy--tNVTVLDPYpV------PS--AiSAGNDVNKVISSGqYSNNKdeievnEI 72  Aspergillus fum...
Q0CK33         8 SILIIG-AGTWGCSTALHLa-RR---Gy--tNVTVLDPYpV------PS--AiSAGNDVNKIISSGqYSSKKde---vEV 69  Aspergillus ter...
Q92261         9 KIVIVGgGGTMGSSTALHL--IRs--GytpsNITVLDVYpI------PS--L-QSAGYDLNKIMSIrLRNGPd------- 68  Penicillium jan...
O43029         6 SVIIVG-AGVFGLSAALELt-KRg--Gy---TIKILDRApP------PV--IdGSSVDANRIIRSd-YADAVy----cS- 64  Schizosaccharom...
XP_011394908  31 SILIIG-SGVFGLTTAYALs-RRh--DfvntTITVVDRAdPsnpdvfPA--PdAASVDTSRIIRAd-YPDAAy----aA- 98  Neurospora cras...
Q18006         6 DVVVVG-AGIFGSCTAYNC--QKiglK-----TLLLEQF-E------LGhkN-GSSHGKSRITRYAh-TEVEy------- 61  Caenorhabditis ...
3SM8_A        66 -ALTA-ASRAFF--DNPPAG-----FCEH-PL-LSPRPEMVV--DFsDDp----------------------EE--L--- 105 Pseudomonas aer...
EWG51937      65 cRLAL-EA------QDIFES------DPLwMPhFHKAGVFWV--CR-SDy----------------------AQdvI--- 103 Fusarium vertic...
Q9UTM9        64 --LAL-EAMEKWrnDPELSS-----V-------YFECGRLST--IS-KDpy--------------------rAR--Fdev 103 Schizosaccharom...
4WCT_B        92 sTFTR-AALKAWktDPVFQP-----Y-------FHETGFIIS--GH-TPal--------------------iDH--I--- 130 Aspergillus fum...
3DJE_A        73 --LAE-EAFNGWknDPLFKP-----Y-------YHDTGLLXS--AC-SQeg--------------------lDR--L--- 109 Aspergillus fum...
Q0CK33        70 nEIIAeQAFNGWknDPIFKP-----Y-------YHDTGVVMS--AT-Tq-----------------------EG--L--- 106 Aspergillus ter...
Q92261        69 lQLSL-EALDMW------KN------DPLfKPfFHNVGMLDC--S--Ss----------------------qEG--I--- 104 Penicillium jan...
O43029        65 --MGI-DALEEWrtNPLFKE-----Q-------FYGSGLMFV--GR-Dn----------------------vEY--R--- 99  Schizosaccharom...
XP_011394908  99 --LAA-EAQLQWrqQTHPDDlgsegR-------YSESGLLVV--AD-GPapppgtpvapgtsvidkskltgmDY--A--- 160 Neurospora cras...
Q18006        62 vDLVG-DAYNQI--FELERI-----RGE--KL-WKKTGLLWVstG--NEv----------------------EK--I--- 101 Caenorhabditis ...
3SM8_A       106 --RRQYESg-----kA-LVP--QMR-L-LDA--EqAC--SIVpvlrrD-----KVFGA--TY-DPTG-ADIDTDALHQGY 160 Pseudomonas aer...
EWG51937     104 ---NNYKK---------LGRasDIQvYtIEE----AK--KLYg----GlyeeaDYTGAkeVLvNRNS-GWGAAGDSLRAV 160 Fusarium vertic...
Q9UTM9       104 aqRNLRKLl------GdSAL------InLSSs-EeIR--KKYp----SlfsnsPLRSDmqAV-VNEHaGYANSAASLKLL 163 Schizosaccharom...
4WCT_B       131 --RKDEVEp------SeTNF------VkLETa-EdFR--RTMp----PgvltgDFPGWkgWL-HKSGaGWIHAKKAMISA 188 Aspergillus fum...
3DJE_A       110 --GVRVRPg------EdPNL------VeLTRp-EqFR--KLAp----EgvlqgDFPGWkgYF-ARSGaGWAHARNALVAA 167 Aspergillus fum...
Q0CK33       107 ---ERLGVr-----vRpED---EPDvAeLTRp-EqFR--QLA-----PgvlkgNFPGWrgYH-IRSNaGWAHARNALVAA 166 Aspergillus ter...
Q92261       105 ---ASLRRkhqdlidAnIGLekTNI-W-LESedD-IL--AKA-----PhftreQIKGWkgLF-CGDG-GWLAAAKAINAI 169 Penicillium jan...
O43029       100 --DMSLENl------TkMGVs----aAkFQTt-EeLR--KLFp----KwigelNDGEAg-YA-NFSS-GWANAEQSVKSV 157 Schizosaccharom...
XP_011394908 161 --RFSWANv------LsLASsdPELaArIKEc-PnTD--AIKa----AlgtggSSGSWg-YI-NGLS-GWANAGASMAWL 222 Neurospora cras...
Q18006       102 --HTNLKL---------KGIkhEV----IKG----TEvgKRYp----QfkfddSW-NG--LI-DPMG-GVIYADKWLNAF 153 Caenorhabditis ...
3SM8_A       161 LRGIRRNQ-GQVLCNHEALE-I-Rr--VdgAWEV-------------RCDa-GS-----------YRAa--vLVNAAGAW 208 Pseudomonas aer...
EWG51937     161 TREAMKLG-VKYIVA-DVAT-VqIengR--ATGI--------------QTakGEii--------sADT----VILSTGAY 209 Fusarium vertic...
Q9UTM9       164 ELKARELG-VEFVFG-KA-G-K--------FKKFvvnhsetdidkndNHV--SVqtedg--tiyhADT----ILLAVGAY 223 Schizosaccharom...
4WCT_B       189 FNEAKRLG-VRFVTG-SPEG-N--------VVSLvye--------dgDVV--GArtadg--rvhkAHR----TILSAGAG 241 Aspergillus fum...
3DJE_A       168 AREAQRXG-VKFVTG-TPQG-R--------VVTLife--------nnDVK--GAvtadg--kiwrAER----TFLCAGAS 220 Aspergillus fum...
Q0CK33       167 AREAQRLG-VRFVAGSPQGR-V--------ITLIf-----------eNNDvkGAvtadg--kiwrAEQ----TILCAGAA 219 Aspergillus ter...
Q92261       170 GTFLKSQG-VKFGFG--SAGtF--------KRPL--------------FApdGAtcsgv-etvdgTKYfadkVVLAAGAW 223 Penicillium jan...
O43029       158 VNYLAHAG-VSFISG-PE-G-T--------VEELite--------enVVK--GVrtttg--aymaEKL----IFAT-GAW 208 Schizosaccharom...
XP_011394908 223 YKRVRAEGrINFVA-----G-E--------VTNLevs--------gnTVT--GArlsdg--rvlsADL----VMVSAGAW 272 Neurospora cras...
Q18006       154 RDEFKKIG-GIIHDREIVLS----------HSEIs-----------------NNlfvttnksrysSKK----IIFTVGCW 201 Caenorhabditis ...
3SM8_A       209 cdaia---------glagVrPlGL--QP-----KRRSAFIFAPPPG------------IDCHDWp--------------- 245 Pseudomonas aer...
EWG51937     210 taklley-----saarhnL----PdlRSgdritAAGITTGMVTLDDqsfa-----kmkDMPVGFqgytyrhnspfigslp 275 Fusarium vertic...
Q9UTM9       224 lnay------------------lntsHR-----VCAKGLPVAHIQLtdee-----fktYKNMPI---------------- 259 Schizosaccharom...
4WCT_B       242 sdsl------------------ldfkKQ-----LRPTAWTLCHIQMgpee-----vkqYRNLPV---------------- 277 Aspergillus fum...
3DJE_A       221 agqf------------------ldfkNQ-----LRPTAWTLVHIALkpee-----ralYKNIPV---------------- 256 Aspergillus fum...
Q0CK33       220 agqfldfkdqlrptawtlV-H-IQl-KP-----EERAQYKNMPVVFniekgf-ffepdEERGEI---------------- 274 Aspergillus ter...
Q92261       224 sst------------------lvDleDQ-----CVSKAWVFAHIQLtpqe-----saqYKDVPV---------------- 259 Penicillium jan...
O43029       209 tasll-----------------pndhTR-----FLATGQPVAYIKLtpee-----yirFLTNPV---------------- 245 Schizosaccharom...
XP_011394908 273 tgrl------------------vdltGQ-----AIATGQVLGYIDLtpee-----eaqLAHMPV---------------- 308 Neurospora cras...
Q18006       202 i---------------------tKf-LPdlkfnIEPISISVCYWKTknesdshllnedHYPVVIa--------------- 244 Caenorhabditis ...
3SM8_A       246 mLVSLDESFYLKP---D-A-----G---ML--Lg--SpaNa----------------------------DPVEA--HDVQ 279 Pseudomonas aer...
EWG51937     276 pTKDREIKWWGRNi-fSnH-----R---AV--LpgrVvsApp-------------------------deKDYAQ--WKVP 317 Fusarium vertic...
Q9UTM9       260 -IFDPDCAYAFPPy-pVtK-----L---IK--La-sTgyEyvcnvetdyde-------nskvvsiphsgPSKSSl--PKY 317 Schizosaccharom...
4WCT_B       278 -LFNIAKGFFMEPd-eDkH-----E---LK--Ic-dEhpGycnflpdpn-----------rpgqeksvpFAKHQi--PLE 331 Aspergillus fum...
3DJE_A       257 -IFNIERGFFFEPd-eErG-----E---IK--Ic-dEhpGytnxvqsa-------------dgtxxsipFEKTQi--PKE 308 Aspergillus fum...
Q0CK33       275 -KICDEHPGYTNMttgAdG-----R---VRs--------------------------------------iPFEK--TQVP 305 Aspergillus ter...
Q92261       260 -VYDGDYGFFFEPn---eH-----GvikVCdeFpgfSrfKlhqpyg-----------------atspklISVPRshAKHP 313 Penicillium jan...
O43029       246 -YLDFDTGFYIFPp-tPdG-----Y---LK--Fa-rHgyGftrmqnlksg---------kvesvppkkpLVSPIl--PKE 301 Schizosaccharom...
XP_011394908 309 -ILNLSTGLFVIPp--RnG-----V---LK--Va-rHayGylnpttlsvpplasfvttpaaavslplttLTDPTlqIPTE 374 Neurospora cras...
Q18006       245 qEMDLQVFHYSLPd---tDypgsmK---FCyhFg-----------------------------------dALTQ--DLAH 281 Caenorhabditis ...
3SM8_A       280 PEQLDIa----TGMYLIEEA--TTLtiRR-----PE----H--TWAGLRSfvADGDLVAGY---AanAE-GFFWVAAQGG 338 Pseudomonas aer...
EWG51937     318 NSLKED-----IDNANRLFF--GS---KGahwkyEK----HriCWDAFTS---SGDFIISPha----gAkGLYVATCGSF 376 Fusarium vertic...
Q9UTM9       318 --AIIQ-----MRRFLDTFL--PDL--ADr---sLIn--tKm-CWI-SDT--EDANFLIDKv--P--QFdNVFVANGDSG 373 Schizosaccharom...
4WCT_B       332 --AEAR-----ARDFLHDTM--PHL--ADr---pLSf--aRi-CWD-ADT--PDRAFLIDRh--P--EHpSLLVAVGGSG 387 Aspergillus fum...
3DJE_A       309 --AETR-----VRALLKETX--PQL--ADr---pFSf--aRi-CWC-ADT--ANREFLIDRh--P--QYhSLVLGCGASG 364 Aspergillus fum...
Q0CK33       306 REAEMR-----VRKLLSETM--PQL--ADr---pFSf--aRi-CWC-ADT--PNREFIIDRh--P--EYpSLVLGCGASG 363 Aspergillus ter...
Q92261       314 TDTYPDsseetIRKAIARFM--PRF--KDkelfnRS----M--CWC-TDT--ADANLLICE---Hp-KWkNFILATGDSG 376 Penicillium jan...
O43029       302 --AELD-----LRRNLQRTYg-EEI--SQr---pFYk--tRi-CYY-TDT--ADAEFVFDYh--P--DYeNLFVCTGGSG 358 Schizosaccharom...
XP_011394908 375 --GADD-----LRRALHEMVplPSL--RDr---pFSk--tRi-CWY-SDT--PTADFIVDYh--P--KYkGLFVATGDSG 432 Neurospora cras...
Q18006       282 PAQRSQrcidlPAKFIQKYM--PVV--DG-----SAptriDkcIYT-NSP---DDHYIIGTiptK---NpNILVGGCGSG 345 Caenorhabditis ...
3SM8_A       339 YGIQTSAAMGEASAAL 354 Pseudomonas aeruginosa
EWG51937     377 HGYKFFPVLGKYVVQM 392 Fusarium verticillioides 7600
Q9UTM9       374 HAFKFLPNIGRYIAQR 389 Schizosaccharomyces pombe 972h-
4WCT_B       388 NGAMQMPTIGGFIADA 403 Aspergillus fumigatus
3DJE_A       365 RGFKYLPSIGNLIVDA 380 Aspergillus fumigatus
Q0CK33       364 RGFKYLPSIGSIIADA 379 Aspergillus terreus NIH2624
Q92261       377 HSFKVLPNIGKHVVEL 392 Penicillium janthinellum
O43029       359 HGFKFFPILGKYSIGC 374 Schizosaccharomyces pombe 972h-
XP_011394908 433 HAFKFLPVIGEKIADV 448 Neurospora crassa OR74A
Q18006       346 SGFKVAPGIGKALAEM 361 Caenorhabditis elegans
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