1L7E,1X15,2EEZ,2VOE


Conserved Protein Domain Family
AlaDh_PNT_C

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pfam01262: AlaDh_PNT_C 
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Alanine dehydrogenase/PNT, C-terminal domain
This family now also contains the lysine 2-oxoglutarate reductases.
Statistics
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PSSM-Id: 279586
View PSSM: pfam01262
Aligned: 75 rows
Threshold Bit Score: 176.521
Threshold Setting Gi: 81539017
Created: 25-Jul-2016
Updated: 4-Aug-2016
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
1L7E_C  150 IDGAYEFARAFPMMMTAAGTVPPARVLVFGVGVAGLQAIATAKRLGAVVMATDVRAATKEQVESLGGKFITVddeamkta 229  Rhodospirillum rubrum
Q24858  708 IEASNKFGRLLMGQVTAAGKSQPANVLVIGVGVAGLAAISTAKALGAQVKAFDTRKAAKEQAESVGAEFCTVsvdedaen 787  Entamoeba histolytica
Q18031  171 IEAANHFGRFFTGQITAAGKVPPAKVLVIGGGVAGLSAIGTSRGMGAVVRGFDTRAAVKEHVESLGAQFLTVnvkedgeg 250  Caenorhabditis elegans
Q6NYQ7  201 VLAANNFGRFFTGQITAAGKVPPAKVLIIGGGVAGLAAAGSARAMGAIVRGFDTRAAALEQFKSLGAEPLEVdikesgeg 280  zebrafish
Q7RV12  207 LEASNVFGRFLTGQVTAAGKIPPCKVLVIGAGVAGLSAIATARRMGAIVRGFDTRSAAREQVQSLGAEFIEVelqedgsg 286  Neurospora crassa
P73496  164 IEAANRFGRFFTGQITAAGKVPPAKVLVIGAGVAGLAAIGAAKSLGAIVRAFDTRPVVKEQVESLGGEFLLLdfkedgtg 243  Synechocystis sp. P...
Q7VL24  143 IEAANVFGSFFTGQITAAGKVPPAKVLVIGAGVAGLAAIGAANSLGAIVRAFDSRPEVKEQVKSMGAEFLAIdfeedags 222  [Haemophilus] ducreyi
Q9F3D4  151 IEAAHVFGRFFTGQVTAAGKVPPAKVLVAGAGVAGLAAVGAASSLGAIVRATDPRPEVADQVRSLGGEYLAVdvaqeesa 230  Streptomyces coelic...
Q6AA35  182 VEAAFAYGRTFGGQVTAAGKVPPAKVFVIGTGVAGLAALGAANSMGAEVYATDVRPETAEQVQSMGAIFLHVrtgdsdqg 261  Propionibacterium a...
1X15_A  150 VEAAHEFGRFFTGQITAAGKVPPAKVMVIGAGVAGLAAIGAANSLGAIVRAFDTRPEVKEQVQSMGAEFLELdfkeeags 229  Escherichia coli
1L7E_C  230 etaggyakemgeefRKKQAEAVLKELVKTDIAITTALIPGKPAPVLITEEMVTKMKPGSVIIDLAVEAGGNCPLSEPGKI 309  Rhodospirillum rubrum
Q24858  788 kf--gyanaasqrlIDAEYALFRQLLPETDIVITTANVPGKKSPILITQDMVDSMKIGSVIVDLAAANGGNCEVTRSGET 865  Entamoeba histolytica
Q18031  251 gg--gyakemskefIDAEMKLFADQCKDVDIIITTALIPGKKAPILITEEMIKSMKPGSVVVDLAAESGGNIATTRPGEV 328  Caenorhabditis elegans
Q6NYQ7  281 qg--gyakemskefIEAEMKLFAKQCLDVDIIITTALIPGRKAPVLITKEMVETMKDGSVVVDLAAEAGGNIETTVPGEL 358  zebrafish
Q7RV12  287 ag--gyakemspefIAAEMKLFTEQAQEVDMIITTALIPGKPAPKLITKAMVEIMKPGSVIVDLAAEAGGNCEVTQPGKL 364  Neurospora crassa
P73496  244 qg--gyakvmseefIAAEMALFAAQAKEVDIIITTALIPGRPAPKLITEPMVKSMRAGSVVVDLAAEQGGNCEVTKPGEV 321  Synechocystis sp. P...
Q7VL24  223 gd--gyakvmseefNRRSMELYAEQAKDVDIIITTAAIPGKPAPRLITKEMVDSMKPGSVVVDLAAATGGNCDYTKAGEV 300  [Haemophilus] ducreyi
Q9F3D4  231 dg---yakatsadyDRAAARLYHEQARDVDVVITTALIPGRPAPRLLTAADVAAMRPGSVVVDMAAAQGGNVEGTVAGRT 307  Streptomyces coelic...
Q6AA35  262 vssdgyaketsddyNARAAELYMEQAGKDDVIITTAAIPGKPSPKLITAEMVYAMKPGSVIVDLAALGGGNCELTRPGES 341  Propionibacterium a...
1X15_A  230 gd--gyakvmsdafIKAEMELFAAQAKEVDIIVTTALIPGKPAPKLITREMVDSMKAGSVIVDLAAQNGGNCEYTVPGEI 307  Escherichia coli
1L7E_C  310 VVK-HGVKIVGHTNVPSRVAADASPLFAKNLLNFLTPHv-dKDTKTlVMKLE------DETVSGTCVTRDGAIVH 376  Rhodospirillum rubrum
Q24858  866 YLYdNRITIIGQTDYTVKMSPQASQLYSQNIFNFLNLIc-kKASDF-TIKLE------EPIVRQMVVCSAGQKMW 932  Entamoeba histolytica
Q18031  329 YVK-HGVTHIGFTDLPSRLPTQSSELYSNNIAKFLLHLg--KDKTF-FVNEE------DEVARGALVVRDGQMKW 393  Caenorhabditis elegans
Q6NYQ7  359 SVH-KGVIHVGYTDIPSRLPTQASTLYSNNITKLIRAIspdKETFYfDVKNEfdfgtmDHVIRGSVVMQDGKVLF 432  zebrafish
Q7RV12  365 INY-KDVKIIGYTDLPSRLPTQSSTLYSNNITKFLLSMa-pNNQEY-GIDLQ------DEVVRGAIVINKGNILP 430  Neurospora crassa
P73496  322 YEY-EGVTIIGYTDLPSRMASQSSQLYGTNLWHLLKDMg--GSEAF-KVDVE------DEVIRGALVSHEGKITW 386  Synechocystis sp. PCC 6803
Q7VL24  301 VITdNQVKVIGYTDFPARLPTQSSQLYGTNLVNLLKLLtpnKDGQI-AINFD------DVVVRGVTVIRDGEVTW 368  [Haemophilus] ducreyi
Q9F3D4  308 VVTgNGVTVIGYTDLAARLPAQASQLFGTNLVNLLRLLtpgKDGRI-VIDFD------DVVQRTVTVVRAGTVTW 375  Streptomyces coelicolor
Q6AA35  342 YVTdNGVTIIGYTDLPSRLPGQASQLYGTNLVNLLKLAtpeKNGEL-VLNFD------DEVIRTMTVCHEGQVAF 409  Propionibacterium acnes
1X15_A  308 FTTeNGVKVIGYTDLPGRLPTQSSQLYGTNLVNLLKLLckeKDGNI-TVDFD------DVVIRGVTVIRAGEITW 375  Escherichia coli
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