4PK5


Conserved Protein Domain Family
IDO

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pfam01231: IDO 
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Indoleamine 2,3-dioxygenase
Statistics
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PSSM-Id: 307406
View PSSM: pfam01231
Aligned: 188 rows
Threshold Bit Score: 386.088
Threshold Setting Gi: 443920505
Created: 13-Jul-2016
Updated: 4-Aug-2016
Structure
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Program:
Drawing:
Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
4PK5_A        31 ISKEYHIDEEVGFA-LPNPQENLPDfYNDWMFIAKHLpd---------------lIESGQLRERVEKLNMLSIDHLTDHK 94  human
ELU40446     123 SCFEF--DAQTAFMpPEPPLSRLDGdYEQWELLLDAAftnftcpgdeesvpesqvQFGECWRQSVRKLPVLSIQPLEFDL 200 Rhizoctonia sol...
XP_003034864   1 ----FDVDANTGFMpRR-PLPKLRGkFDLWEAALRSAtetlvlgsdeseeaaqkhPQGSRWRKAIEQLPVLDVDELTCDL 75  Schizophyllum c...
XP_003027519 100 dLPEFDIDGETGFVpPR-PLPRLQGdYQIWEDTLREAagrvslgcdesdeaisrrAYSKSWRQKVDSWPVLDTSDF--GL 176 Schizophyllum c...
EMD38214      25 epEEFDVHPQSGFFpPQ-PLQKLPEaFGIWEQLLADAhscltlsndyseeavakrPKGELWRNRVRDMPLISIVNLTENS 103 Ceriporiopsis s...
EPS99019      17 NPSDFDVDSKSGFFpPA-PLPRLPSeYDAWEAAFAAApsvialagdkseealqkrGDGASWRSTVRSWPVKDVCILCGDI 95  Fomitopsis pini...
XP_006458001  39 sPSDFDIDLQTGFFpTT-PLSRLPSsFDLWEDGLASAagrlplgndsseealarrEFSRNWRDDVKSWPVISIQELGSDL 117 Agaricus bispor...
XP_001874913  41 spAAFDVDSRTGFFpRQ-PLPKLPHtFDIWEDALRNAdgnlslgedesetalakrEFGARWRETIQSLPVLDTSVLHTNL 119 Laccaria bicolo...
XP_001833050 130 spySYDINQHTGFFpPE-PLPKLPPsYEIWEQALRDAngnlslgedesedalerrPYGLEWRARIQEWPVLDTAPLHKNP 208 Coprinopsis cin...
XP_007846503  50 SQRDFDIDPITGFVpSK-PLPRLSAeYELWEQALLDGldniklgedtsdqaiaarPAAERWRSTVSTWPVLSIDKILRNR 128 Moniliophthora ...
4PK5_A        95 -SQRLARLVLGCITMAYVWGk-GhGDVRK------------------VLPRNIAVPYCQLSKKLELPPILVYADCVLANW 154 human
ELU40446     201 rRARRAHHVLAFITQFYVQSlpP-RDCTFdrp-------------piIIPAPIAIPFVGVSRQLDIAPIVTYADTVLWNW 266 Rhizoctonia sol...
XP_003034864  76 rLLQRAHYVLAYLIHFYVHSi-Pdgele--------------pgapiTIPRPLAAPITAVAQHLRMAPVLTYADTILWNV 140 Schizophyllum c...
XP_003027519 177 kEQQRAHYVLAFILHYYAHSi-Pdddmd--------------kcspiHIPKSLSKPLVAVSRALRIAPVLTYADTIIWNL 241 Schizophyllum c...
EMD38214     104 q-LQRAHMVLAWILHFFIHSm-P---QSEkep-------------qvRIPQSLAVPLVEVSKILRIAPVATFADVVLWNY 165 Ceriporiopsis s...
EPS99019      96 rLLQRAHMVLASLMHFYVHSl-P---SSda---------------aiLVPKSISVPLVEVSRELGIAPVLTFADTVLWNW 156 Fomitopsis pini...
XP_006458001 118 rLLQQAHYVLSWLVHLYVHSv-P---LDPtle-------------viVVPQSIAVPLVEVSKILQIAPVLTFADTVLWNY 180 Agaricus bispor...
XP_001874913 120 rLSQRAHYVLAWLVNLYVHSi-Psssdd---------------sdpvHVPKSLALPLVQVSRHLGCAPVLTFADTVLWNW 183 Laccaria bicolo...
XP_001833050 209 rLAQRAHLVLAWLVSFYVHSi-P---PTTstantssgsdsedraeplRVPKSLAVPLMQVSRHLGLAPVLTFADTVLWNW 284 Coprinopsis cin...
XP_007846503 129 aLACRAHLVLAWLVHLYVHSi-P---PMAepe-------------piKVPACLAVPLVAVSRHLGIAPVLTFADTVLWNW 191 Moniliophthora ...
4PK5_A       155 kkkdpnkplTY---ENMDVLFSFRDGDCSKGFFLVSLLVEIAAASAIKVIP--TVFKAM---QmqeRDTLLKALLEIASC 226 human
ELU40446     267 eli---epsQPmssSNIRIKDLFTRDPQEEHFFLTSARIEIRGLEAMDIMAkcLRQIEEgvtSeaeQVRLASNLTRLAQV 343 Rhizoctonia sol...
XP_003034864 141 eki---nedGPltmDNLRTETLFSGTEDESAFYMSQVRCELRGAELLGIMAdiANLPPLrarDaamVAEVEGALRRLSGD 217 Schizophyllum c...
XP_003027519 242 eli---npdGPttpDNLQNETLFSETEDESAFYMSQVNCELRGAELLTCMQelSQMTKEdakNpdnLPCVSCMLTRLKLV 318 Schizophyllum c...
EMD38214     166 eli---dptLPltpQNIKYDNLFSGTETERQFYVVSALVEMKGVEMLKIFEdfYNL--QdptTpsaVEKIAVDLVQLKKI 240 Ceriporiopsis s...
EPS99019     157 eli---dpsLPvevNNMRYLNVFSGTETERAFYLSSAAVELRGVEMLDIFNrfQNLPASshtDahvIAQLAKDLNQLAVI 233 Fomitopsis pini...
XP_006458001 181 eli---npaEPlsvNNIRFRHHFSGTEDEDAFYLSSARAELVGVEMLRIFDeyGRLSPna-gDytaVGKVSRDLIRLSGI 256 Agaricus bispor...
XP_001874913 184 eli---dpdQPlsiDNMQFVNLFSGTEDEKSFYQASAKAELRGVELLRIIDdyNSL-Pni-tDltsISKVSRDLGRLVGI 258 Laccaria bicolo...
XP_001833050 285 eli---hpsRPlspDNIRFVNTFSGTDDEKNFYYASALAELRGVEILRIIDdfNNL-Pig-sDlasTTKVSRDLHRLAGI 359 Coprinopsis cin...
XP_007846503 192 eli---npeGPvtiDNMRFLHAFSGTEDEYNFYKVSATVELHGANILRFIDeyNNL-Pnl-rDttaIFKVACDLRNLTTV 266 Moniliophthora ...
4PK5_A       227 LEKALQVFHQIHDHVNPKAFFSVLRIYLSGwkGNPQ--LSDGLVYEGf-----wEdpkeFAGGSAGQSSVFQCFDVLLGI 299 human
ELU40446     344 VDDITTILDAVREGCDPMFFYFTFRPWIRG--ADQGa-DSPMWFYEGvdg-qgiEm--qCSGPSAGQSALMHAFDVFLDI 417 Rhizoctonia sol...
XP_003034864 218 IDELTEVMKGIRPTCDPHVFYWQIRPWFVG--SSEEh----pWVFEGada--gdDl----lGPSGGQSSLMHAIDVFLSI 285 Schizophyllum c...
XP_003027519 319 IEDLDKLIKSVRPLCDPHLFYWKIRPWFIG--STKEh----pWIFDGeep--gsDl----lGPSGGQSTLMHAIDVWLDV 386 Schizophyllum c...
EMD38214     241 VDELTEIFRLIRTTLDPNIFYWKARPWWSG--AKNTlkKME-WVFEGipd--saVl--dIGGGSAGQSSVMHALDIFLDI 313 Ceriporiopsis s...
EPS99019     234 VNQLTEVFRSMRETVDPVEFYWAVRPWWSG--ATSKgpNHPGWILEGvpngdsaHf--dLGGASAGQSSAMHALDVFLDI 309 Fomitopsis pini...
XP_006458001 257 VDDINEVIKSVRPTCDPHVFYWQVRPWYSG--Sg---sDGPRWKYEGvpk--deKl--lRSGPSAGQSSVMHALDIFLGV 327 Agaricus bispor...
XP_001874913 259 IDDISEIIQSIRPLCDPHVFYWDIRPWFEG--SDAKgpGGPRWIYEGvdd--feKl--dLSGPSAGQSSVMHALDIFLDV 332 Laccaria bicolo...
XP_001833050 360 IEDITEIITSVRSACDPHVFYWDIRPWFEG--SDAKgpGGPGWIYEGvde--aeNl--dLSGPSAGQSSVMHALDIFLNI 433 Coprinopsis cin...
XP_007846503 267 IEELASIMQSVRPIVDPHVFYWDMRPWFEG--SDAKgpSGHGWIYEGaeq--shKl--dLSGPSAGQSTAMHALDVFLDI 340 Moniliophthora ...
4PK5_A       300 QQTagg-----------ghA------------------------------------------------------------ 308 human
ELU40446     418 VHPnsrasrgcsfainfpitppsspgmhgkdindisqcpfaskistvdpaynphvqssrtqadtgldtppltplesevpt 497 Rhizoctonia sol...
XP_003034864 286 DHElrysrtpaptaenrkaD------------------------------------------------------------ 305 Schizophyllum c...
XP_003027519 387 DHMlrykrvpepceankraD------------------------------------------------------------ 406 Schizophyllum c...
EMD38214     314 DHKletkrspppsernlqsE------------------------------------------------------------ 333 Ceriporiopsis s...
EPS99019     310 DHRlatkrapapsepnrraD------------------------------------------------------------ 329 Fomitopsis pini...
XP_006458001 328 DHKkgst--------gkdgH------------------------------------------------------------ 339 Agaricus bispor...
XP_001874913 333 DHKlrqrrypapssenkraD------------------------------------------------------------ 352 Laccaria bicolo...
XP_001833050 434 DHKlqerrypapspenkraD------------------------------------------------------------ 453 Coprinopsis cin...
XP_007846503 341 DHKlrqrrypapseenkraD------------------------------------------------------------ 360 Moniliophthora ...
4PK5_A       309 ----AQFLQDMRRYMPPAHRNFLCSLES-N--PSVREFVlskGDagLREAYDACVKALVSLRSYHLQIVTKYILIPASQ- 380 human
ELU40446     498 vipvdlkipRMRKYMPGGHQLFLDHLRSlKfgPTIRALAqdsTH--LANSYNVALQALSGFRDAHIRVVTRYVICPARSk 575 Rhizoctonia sol...
XP_003034864 306 ----TGFMRRMWRYMPGAHRDFLEHLEQaP--FRVRDLAeetPV--LRDAYDDAVAALKRLRDNHMRIAVLYVVSAGRSl 377 Schizophyllum c...
XP_003027519 407 ----LGFMRRMWRYMPGVHRDFLEYLEAaP--VRLRNLAqevPA--LLEPYDAAVMAMKRLRDAHIGIAVLYVVSAAKEl 478 Schizophyllum c...
EMD38214     334 ----LGFMERMRRYMPGKHREYLEHMASvR--PTVRDVAqnvST--LVVRFDEAVLALKKLRDLHIRVVTLYVVNQTRS- 404 Ceriporiopsis s...
EPS99019     330 ----LGFMQRMQRYMPGKHRAYLTHL------RSVRPLVertPS--LREPYNTAVEALKRLRDFHLRIVAIYVVTKAGSt 397 Fomitopsis pini...
XP_006458001 340 ----GSFMERMRLYMPGKHREYLISLSClS--RSLRELAkeeSI--LRESYNSAVAALQKLRTEHIKIACRYTVSMAHTq 411 Agaricus bispor...
XP_001874913 353 ----HGFMERMRRYMPGKHREYLSSLAAtP--RPIRQLAqstPT--LREPYDNAVLALKRLRDNHIRIACLYVVTMSRTe 424 Laccaria bicolo...
XP_001833050 454 ----HGFMERMRRYMPGQHREFLNVL-StS--RSIRQLAqstPA--LRDAYDTAVTALKRLRDTHIRIACLYVVTMSRSt 524 Coprinopsis cin...
XP_007846503 361 ----HGFMQRMRRYMPGKHRQYLEHLEAtP--RSIRELAqstPM--LREPYNNAVMALKRLRDSHMRIACLYVVTMSHSv 432 Moniliophthora ...
4PK5_A       381 -----------------QpkenktsEDPSKLEAKGTGGTDLMNFLKTVRSTTEKS 418 human
ELU40446     576 tv--------------------vrdPALDSGSVRGTGGTSLVPLLKVYRDETLHr 610 Rhizoctonia solani AG-1 IA
XP_003034864 378 ppgcpls---amarameKkg-------pSGGRSKGTGGSEVSALLKAGRDATRRA 422 Schizophyllum commune H4-8
XP_003027519 479 ppgcpls---mmakameAkg--------pEGKSKGTGGSEVSTLLKAGRDATRRT 522 Schizophyllum commune H4-8
EMD38214     405 -----------------TpsaglvsEVQNEGPARGTGGSSVSILLKAGRDATARS 442 Ceriporiopsis subvermispora B
EPS99019     398 ppe-----------rfaPesegdavGTRKDGPARGTGGSEVSNLLKAGRDATKRA 441 Fomitopsis pinicola FP-58527 SS1
XP_006458001 412 pnsgcpv--lsawnqtpEg--------eKRKKTLGTGGNEVVTLLKHGRDATQRT 456 Agaricus bisporus var. bisporus H97
XP_001874913 425 pgarggcpasamidrlrEsr------lSGRGPVRGTGGNELSLLLKAGRDATRRA 473 Laccaria bicolor S238N-H82
XP_001833050 525 pgsrggcpaaamierlhAnr------lAGKGPVRGTGGNELSILLKAGRDATRRA 573 Coprinopsis cinerea okayama7#130
XP_007846503 433 pdarsgcpasqmlkrleEsr------aSGKGPVRGTGGNELSLLLKAGRDATRRA 481 Moniliophthora roreri MCA 2997
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