2EJA,3CYV


Conserved Protein Domain Family
URO-D

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pfam01208: URO-D 
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Uroporphyrinogen decarboxylase (URO-D)
Statistics
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PSSM-Id: 307389
View PSSM: pfam01208
Aligned: 136 rows
Threshold Bit Score: 182.779
Threshold Setting Gi: 172045690
Created: 13-Jul-2016
Updated: 4-Aug-2016
Structure
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Program:
Drawing:
Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
2EJA_B          2 PKNDLLLRSLRG-EPIGRFPVWLmrqAGRYMPEYRKIRNrVKNFLELCKNVDLATEISLLPLKILGVDAIIIF-----SD 75  Aquifex aeolicus
Q8THF8          5 NLRDRFLSVLKG-KAADRVPVLS---VTQTGTVSLMEKC-GVFWPEAHSNPEKMAALSLAAHEITKLEAVRYP-----YC 74  Methanosarcina...
Q8TSE3          5 DLRDRFLNTLHG-KAVDKVPVLA---VTQTGTVELMRES-GAAWPDAHFDAKKMADLALSAHTFAGLEAVRYP-----FC 74  Methanosarcina...
Q74AG9          2 TSFERVMAAMGG-VETDRPPFTL------TLSLYGARLI-GASPEQYYTSPRLYAEGQDRVAELFGPDILFAP-----FA 68  Geobacter sulf...
Q39S06          2 TAAERVMAVFTG-EKPDRPPFAL------TLSLYGARLI-NAPLASYYADPALYAQGQVRVAELVSPDIIFAP-----FA 68  Geobacter meta...
2_pfamImport    1 TGMQRFQAIMAG-QLPDRVPVLC------NLLDQGAREL-GMSIKEYYRRGENVAEGQLHMRKKYGYDSLLGL-----FY 67 
16_pfamImport   1 TSMERVLTTMSK-HEPDKVPLFL------MCTHYCAKFL-DISIKNYFSKPENVAKGQMMLLRKFNNDCLNPF-----YS 67 
Q2RG09          2 LNYHEILATAMFrPINPHVPVVL-----WAIGQTYAPFA-KIPDNEYYADPAKMLEAQVKFYERF-PDVLTIPgiwpdLG 74  Moorella therm...
Q2RLD3          4 SQWSIIKKCVNM-EELIQVPVGL-----IVDSPWIPGYV-GISTMDYFTIPEKWLEANIKIIKDF-PEIIFLPgfwveYG 75  Moorella therm...
Q024B9          4 DQWETFKRAARR-EKMDRIPMAL-----IVDSPWIPGYL-GIKHMDYYLDPELWFESNLKIMREF-PDIIFIPswwmeYG 75  Candidatus Sol...
2EJA_B         76 ILVPLEPLGV-KVEFVEGEG-PKLSWSGK-----VSDLKKYdPSq--N--AYVYEIIKRVKE----A-QDEVPVIGFAG- 138 Aquifex aeolicus
Q8THF8         75 VTVLSEAMGC-EVSRGTKEIqPYVKVPPLgk--sGNLPEIPdSLlemGriPTVLKATSLLKD----KtEESLPLIVGIE- 146 Methanosarcina...
Q8TSE3         75 LTVLSEALGC-KVNPGRXDIqPSPGSNPFak--ePEKMELPsDFaqrGriPLIKDVTSILRE----KaGEEVPLIAGME- 146 Methanosarcina...
Q74AG9         69 LAREAEAFGS-TVVYHRHGP-PNVVKPVVknaadFMRLADPdPda-hPalLYLRESVRLLAD----GyKGRVPLAGILT- 140 Geobacter sulf...
Q39S06         69 LALEAEAYGA-ELRYHPDGP-PMVRRHPFraprdAASLSPPaIdt-cPglAYLCESVRRLAD----HfCGSVPLAGVLT- 140 Geobacter meta...
2_pfamImport   68 VAMEAEMLGCrSIIYAEDGP-PNVGQLIIsepedIRRLQIPdDMeelPrfRELSACIRILKR----EaAGRFPVIGVVT- 141
16_pfamImport  68 AAHEYAAFGS-EVIFNEAGP-PNAGEPIIknfddILKLQPPdVkn-sKilRNCLETISILKE----EvGMSVPIAGGVL- 139
Q2RG09         75 LMAELGALGA-ELEFPDDAP-PQSRGGAFedireVENWEVPdPkk-aDytSQTLDYLKYFCKhlpeEpRKKWGFLDGHIf 151 Moorella therm...
Q2RLD3         76 MATEPSGFGC-KINFYPDRT-PTINHIINsp-eeAEDIFVPnPqt-dGlmPFVLNIYRNIEPkv-kDlGRCIKVVAAR-- 148 Moorella therm...
Q024B9         76 MAAEPSILGA-KIKFWQDNT-PSEYHTLYrl-edIDNFPEYeVda-dAfaALTLHRIKMIKPri-eDlGYILPMVTA-R- 148 Candidatus Sol...
2EJA_B        139 --APFTLLSYLIeggaskDFKSTKLFMWENPKEYKR-LMDILTETVLAYLKEQIKAGAD---VVQIFD--SWVNNLSLED 210 Aquifex aeolicus
Q8THF8        147 --SPAALCSRLL------GANNYLGQLLRSPDYIRE-CLEINTEACIEYANALFEEGAD---AVCVPDgiSGPDLLSLDI 214 Methanosarcina...
Q8TSE3        147 --GPASLASRLL------GTYNFLTWMIRRPETLSQ-CLKVTGATCSAYAEILSEAGAD---AVCIVDgiAGPDMLDPRH 214 Methanosarcina...
Q74AG9        141 --APVDLPAIIM------GIDAWLETLLFEPELASA-VLEKTGRHFVAMASRLLGDGAD---FVAMPVmfFNTALVTSRI 208 Geobacter sulf...
Q39S06        141 --APVDLPAMLM------GLDGWLETLLFEPALAET-VLAAATEHFAAMAGALAAAGAA---CIAIPLmlANPTLVTPEV 208 Geobacter meta...
2_pfamImport  142 --ASFTLPAMLM------GISGWLNLFLSGPTELRSlLLEKCSQFCRRQILALRQAGAD---LIVYTNsvGTATFVTSRQ 210
16_pfamImport 140 --SPFSLPILQM------GFDKYIELIYEKPELLEH-LIKINERFCTEWANMQLAAGAS---FITTIDsmSVSSIIPKSI 207
Q2RG09        152 cgGPGEISGLLL------GYDKFSYAMYDYPQLVHI-LLRKVTDFIKSYIDAQIEIVGEp-kRVIIWD--HIPGMLSREL 221 Moorella therm...
Q2RLD3        149 --GPLTIASHLM------GVTNFLIGLKTDPANTHK-LLKKTTTLAKNWLEAQAEVLSEv-eGIMVLD--DIVGFLSQDD 216 Moorella therm...
Q024B9        149 --GPLCTAGFVR------GTTHFMIDIVEDPKGAHR-LIDLCTRVVIDWLKAQQAVMGDkveGIFILDdiVG--FINEEH 217 Candidatus Sol...
2EJA_B        211 YGEYVYPYVNYLISELKD-FsdtPVIYFFRGSS-S-FIDLAVD-YRADALSVDWSV-DIpELFKiyDK----GFQGNLEP 281 Aquifex aeolicus
Q8THF8        215 FDRLIKPAYRRFCKKARG-----MKILHMCGNAfP-FLETLSE-CGFEGISVEEKVwDLkGAKK--SLgkgiCLIGNVAS 285 Methanosarcina...
Q8TSE3        215 LEALIRPEYESFCKSGKG-----IKLIHVCGNStP-ILKTLSR-CGFQGISIEEKVtDLqTAKK--LVgsktKLIGNLSS 285 Methanosarcina...
Q74AG9        209 AAERIVPALAAAFAQVPG-----PLVFHHGGNRiApFLGELAElPGVAGFVIDPRD-SFqDARA--RVgdgrVLLGKLNG 280 Geobacter sulf...
Q39S06        209 ISRSIVPPLAQAFARTPI-----PIILHHGGNPaMpFLPLVKDlPNVAGFVIGPGD-SFaAARS--IVgeekLILGNLNG 280 Geobacter meta...
2_pfamImport  211 FHDLVLPSVLRDLEGIGTgD---LVYFNGGGQInP-QLKTLVEqTPLRAFYINPFD-DIgEAAG--MLngqaLLVGTIND 283
16_pfamImport 208 YLKTGFLSAKRTIPTIKS-----DVAIATSSASsSsILEEILE-SGIKAILVSHTD-DLaEIKK--KVgqraTLLGNLNG 278
Q2RG09        222 FDEFIHPYMKEVFTHVEKaT---LRIYHNENNYpH-LLDLMRD-IPANVCHIGPKH-DLvESKR--VLk--kCVMGNVHP 291 Moorella therm...
Q2RLD3        217 YLEFAHPYLKEIFDAFPQc----IKMYHNDSDNiV-CFSYLQD-LSINIFNFTHLQ-DIaKVRQ--LVgnkiCLLGNIPP 287 Moorella therm...
Q024B9        218 YLEFAHPYLKRICDAFPDnW---VKLYHNDAEVdA-CLDHLPD-AGFNVLNWGKQR-HItEVKR--RVgdrmCLMGNVNP 289 Candidatus Sol...
2EJA_B        282 -AVLY-ASEEVIEEKTLGLLRri-pVKTRYVFNLGHG---LAPDMELEKVKYLVDLVKSF 335 Aquifex aeolicus
Q8THF8        286 sSTLLfGSPEDVKAEARKSLEgg-----vdILAPSCG---IAPLTPLENMKALVEARDEY 337 Methanosarcina acetivorans
Q8TSE3        286 sGIMLnGTCEEIKLEAQKCLEdg-----idILAPGCG---IAPKTPIKNIRAMVEARDEY 337 Methanosarcina acetivorans
Q74AG9        281 p-LLGlLTPDDACRVTAEILAdrrdDRHFIFASSAAD---VPWNTPPETISAVADTIRQW 336 Geobacter sulfurreducens
Q39S06        281 p-VLNrLTPEQAGARAAAILAdrrdDPHFVLASSSAD---VPLDTPLETLLAVRAAVEGH 336 Geobacter metallireducens GS-15
2_pfamImport  284 i-RLInGSKEEIDDQVKGIMEqg-----krVTGFAFGtlmMPYVIPEENIRAMLESAYRY 337
16_pfamImport 279 i-EMCrWTRFDAEYNVKEAIRkagvGGGFILCDSLGD---IPYQVSEDILYEISESVNKW 334
Q2RG09        292 iQELLlGTNEEIEAKCKTIIEta-gRGGGLWLSTGGG---MAPETPVEKMQVLIDCTKKY 347 Moorella thermoacetica ATCC 39073
Q2RLD3        288 lDVLTnGTPDMVAEAAVNCLNqh-gNKAGIILSAGGG---TSPGTPGRNIHALIKATANY 343 Moorella thermoacetica ATCC 39073
Q024B9        290 lEIAVrGTPEEVKDETLEVLEga-gGE-GIILSVGGG---VSPGMPRENILAMLEALQEF 344 Candidatus Solibacter usitatus Ell...
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