3V8V


Conserved Protein Domain Family
UPF0020

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pfam01170: UPF0020 
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Putative RNA methylase family UPF0020
This domain is probably a methylase. It is associated with the THUMP domain that also occurs with RNA modification domains.
Statistics
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Aligned: 14 rows
Threshold Bit Score: 199.121
Threshold Setting Gi: 81784987
Created: 14-Mar-2019
Updated: 18-Jul-2019
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
3V8V_A 162 RGYRDRAGIAPIKETLAAAIVMRSGWQPGTPLLDPMCGSGTLLIEAAMLATDRAPGLH---------------------- 219 Escherichia coli ATCC...
Q9K0V4 165 RGYRLDTGEAPLRENLAAGLLLSAGYDGTQPFQDPFCGSGTIAIEAAWIAARRAPGMMrrfgfeklqnfdktlwsdlrrr 244 Neisseria meningitidi...
P50840 164 RGYRVDQGGAPIKETLAAALVQLTNWTPDRPFVDPFCGSGTIAIEAALIGQNIAPGFNrdfvsedwewigkdlwnkarle 243 Bacillus subtilis sub...
Q57880 166 RGYRVFNHPAHLNATIASSLVYLSDWKDDEMLLDPMCGSGTIPIEGALMKRNIPPGKFrenkygfkfidi--fgyelldk 243 Methanocaldococcus ja...
O28105 192 RWWRVYNHPAHLNAAIACGMLRIADWKVDESLIDPMCGSGTIPIEAALMVRNVP--NLrdfaykk------------lce 257 Archaeoglobus fulgidu...
O26820 160 PHKRPFFYPGSMSPKLARCMVNLSGVKAGDRILDPFCGTGGILIEAGLMGVRVV-------------------------- 213 Methanothermobacter t...
O29011 149 PDRRPFLMPSAIKPKLARALVNLTGVLEGETLLDPMCGTGSFLIEAGLMGINPI-------------------------- 202 Archaeoglobus fulgidu...
Q9YAV9 170 PGRRPFFKPGPLSPRLSRAFVNLSRLQRGGSFADPFCGTGGFAIEACLLGASRIA------------------------- 224 Aeropyrum pernix
Q9RTT7 193 RAWRECNMGGGLNATIAYAMHKLAGQRDEDRIFNPMSGSGTLLIERALLGPYAA-------------------------- 246 Deinococcus radiodurans
P97770 295 RNITHFG-PTTLRSTLAYGMLRLCEPKPTDVIVDPMCGTGAIPIEGATEWSHCYHIAG---------------------- 351 house mouse
3V8V_A 220 ---RgrwgfsgwaqhdeaiwqevkaeaqtrarkglAE---YSSH--FYGSDSDARVIQRARTNARLAGIGELITFEVKDV 291 Escherichia coli ATCC...
Q9K0V4 245 aeaQ-------------------------------TRp--VRAP--IAGSDNDRRIVQTALDNARRAGVDDIVSFSVADA 289 Neisseria meningitidi...
P50840 244 veeK-------------------------------AN---YDQPltIFASDIDHRMVQIAKENAEEAGLGDLIQFKQMQV 289 Bacillus subtilis sub...
Q57880 244 ikkE-------------------------------IVenkNIYK--IIGLDKNQKYLDGAKDNAKNAEVLDTIEFICGDA 290 Methanocaldococcus ja...
O28105 258 welA-------------------------------FEpneVRLK--LYGMEKFRKHLVGAIRNAVNAGVADTIEFRQGDA 304 Archaeoglobus fulgidu...
O26820 214 ------------------------------------------------GADIDWRMVEGTRENLQHYGITDFEVIRS-DA 244 Methanothermobacter t...
O29011 203 ------------------------------------------------GIDFIEKIVRGCRVNLEYYGIEGSVLLGDAKN 234 Archaeoglobus fulgidu...
Q9YAV9 225 ------------------------------------------------CGDLDWAMVRGGPLNLSRYCPPGIWFYSAWNA 256 Aeropyrum pernix
Q9RTT7 247 ----------------------------------------------LVGVDIDPVAVACARTNLRAAGKEVEVAQVDALH 280 Deinococcus radiodurans
P97770 352 ---D-------------------------------NN---PLAV--NRAANNISSLLTKSQIKDGKTTWGLPIDAVQWDI 392 house mouse
3V8V_A 292 AQLtnPLPKGp-YgtVLSNPPYGERLDSEPAL-IALHSLLGRIMKNQFg---gWNLSLFSASPDLLSCLQLR--ADKQYK 364 Escherichia coli ATCC...
Q9K0V4 290 QSV--R-PNGe-NgiMVSNPPYGVRLEEVRAL-QALYPQLGTWLKKHYa---gWLAAMFTGDREMPKFMCLS--PKRKIP 359 Neisseria meningitidi...
P50840 290 KDF--T-TNl-eFgvIVGNPPYGERLGEKKAV-EQMYKEMGQAFEP-Ld---tWSVYMLTSNENFEEAYGRK--ATKKRK 358 Bacillus subtilis sub...
Q57880 291 TKL--HEKFNe-SdvIIANPPYGIRIGSKRSV-KKLYDEFLSSAKEIMhg-ssRLIVITAEDKMFKDAIAKN--NFEVKE 363 Methanocaldococcus ja...
O28105 305 T-----EMTGe-YdvIITNPPYGLRIHRKGAI-ERLYHSFARAAKRCMnq-nsRLVIITAEHRVFANAAEEA--GLQCTH 374 Archaeoglobus fulgidu...
O26820 245 RDL--R-LDEk-VdaIVTDPPYGISASTAGEKsEKLYREFLDSAHSNLae-ggMICMAAPHYLDLESLIDERf-SIRERY 318 Methanothermobacter t...
O29011 235 LPL--R-DEs--VrgIATDYPYLRSTKAAGTL-DELYSKTSEEFERVLk---kGGRAAIVTNIDVESFFSNF--EIEMKT 303 Archaeoglobus fulgidu...
Q9YAV9 257 AKL--P-LSSnsVdsIATDPPYGRSTTTGRMGyLSLTRAFLNTAVEVLrs-egWIVYAGPTRMSPETLAEDAglRVVKVI 332 Aeropyrum pernix
Q9RTT7 281 TGL--P-SRs--FdlVISDLPWGDAIGSHQSN-ETLYPAFLKEMHRLTsr-rgRLCLLTHELRLFERVMREQs-DWEAKE 352 Deinococcus radiodurans
P97770 393 CNL--PLRTAs-VdiIVTDMPFGKRMGSKKRN-WNLYPACLREMSRVCrpgtgRAVLLTQDKKCFTKALSGMghVWRKVH 468 house mouse
3V8V_A 365 AKNGPLDCVQKN 376 Escherichia coli ATCC 8739
Q9K0V4 360 LYNGNIDCRLfl 371 Neisseria meningitidis MC58
P50840 359 LFNGFIKTDYYQ 370 Bacillus subtilis subsp. subtilis str. 168
Q57880 364 EFNVMFGGLMTR 375 Methanocaldococcus jannaschii DSM 2661
O28105 375 ERFVKYGGLLTK 386 Archaeoglobus fulgidus DSM 4304
O26820 319 SMRMHRSLTRVI 330 Methanothermobacter thermautotrophicus str. Delta H
O29011 304 EERVHGSLTRRI 315 Archaeoglobus fulgidus DSM 4304
Q9YAV9 333 EMFVHGSLTRSI 344 Aeropyrum pernix
Q9RTT7 353 LFQVYSGGHHPK 364 Deinococcus radiodurans
P97770 469 VVWVNIGGLHAA 480 house mouse
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