3V8V


Conserved Protein Domain Family
UPF0020

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pfam01170: UPF0020 
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Putative RNA methylase family UPF0020
This domain is probably a methylase. It is associated with the THUMP domain that also occurs with RNA modification domains.
Statistics
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PSSM-Id: 279509
View PSSM: pfam01170
Aligned: 13 rows
Threshold Bit Score: 198.348
Threshold Setting Gi: 81784987
Created: 13-Jul-2016
Updated: 4-Aug-2016
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
3V8V_B 162 RGYRDRAGIAPIKETLAAAIVMRSGWQPGTPLLDPMCGSGTLLIEAAMLATDRAPGLHrgrwgfsgwaqhdeaiwqevka 241 Escherichia coli K-12
Q55156 172 RGYRPALGNAPLKETLASALLTMAGWTPELPLYDPLCGSGTFLLEAGLQSLNIAPGKFqpgfcfqqwpdfdqdlwhsllq 251 Synechocystis sp. PCC...
P44524 162 RGYREDAGQAPLRETLAAAIVMRSGWQVGSPLVDPMCGSGTLLIEAAQMEAKIAPQLYrlhwgfdfwkahnqsawekvkn 241 Haemophilus influenza...
Q9K0V4 165 RGYRLDTGEAPLRENLAAGLLLSAGYDGTQPFQDPFCGSGTIAIEAAWIAARRAPGMMrrfgfeklqnfdk-tlwsdlrr 243 Neisseria meningitidi...
P50840 164 RGYRVDQGGAPIKETLAAALVQLTNWTPDRPFVDPFCGSGTIAIEAALIGQNIAPGFNrdfvsedwewigk-dlwnkarl 242 Bacillus subtilis sub...
Q57880 166 RGYRVFNHPAHLNATIASSLVYLSDWKDDEMLLDPMCGSGTIPIEGALMKRNIPPGKFrenkygfkfidi---fgyelld 242 Methanocaldococcus ja...
O28105 192 RWWRVYNHPAHLNAAIACGMLRIADWKVDESLIDPMCGSGTIPIEAALMVRNVP--NLrdfaykk-------------lc 256 Archaeoglobus fulgidu...
Q9YEM1 173 RRYRVYDHPAALKASLAYVMLRLAGARDGDTILDPMCGGGTVAVEAALLFETSR-------------------------- 226 Aeropyrum pernix
O26820 160 PHKRPFFYPGSMSPKLARCMVNLSGVKAGDRILDPFCGTGGILIEAGLMGVRVV-------------------------- 213 Methanothermobacter t...
O29011 149 PDRRPFLMPSAIKPKLARALVNLTGVLEGETLLDPMCGTGSFLIEAGLMGINPI-------------------------- 202 Archaeoglobus fulgidu...
Q9YAV9 170 PGRRPFFKPGPLSPRLSRAFVNLSRLQRGGSFADPFCGTGGFAIEACLLGASRIA------------------------- 224 Aeropyrum pernix
Q9RTT7 193 RAWRECNMGGGLNATIAYAMHKLAGQRDEDRIFNPMSGSGTLLIERALLGPYAA-------------------------- 246 Deinococcus radiodurans
P97770 295 RNITHFG-PTTLRSTLAYGMLRLCEPKPTDVIVDPMCGTGAIPIEGATEWSHCYHIAG---------------------- 351 house mouse
3V8V_B 242 eaqtRARkglAEYSshFYGSDSDARVIQRARTNARLAGIGELITFEVKDVAQLTnpLPKGp-YgtVLSNPPYGERLDSEP 320 Escherichia coli K-12
Q55156 252 takaGER---DTLQapLWGSDGDREVIQAAKSNAQQCQLGGKIHWQKLNFADIEppAAEG--V--LICNPPYGKRIGQEE 324 Synechocystis sp. PCC...
P44524 242 eaieLAEekqREIQphFYGFDLDHRVLKKAQKNAQNAGVSHLIKWQQADVAALKnpRLNe--VgtVICNPPYGERLGTTP 319 Haemophilus influenza...
Q9K0V4 244 raeaQTRp--VRAP--IAGSDNDRRIVQTALDNARRAGVDDIVSFSVADAQSVR---PNGe-NgiMVSNPPYGVRLEEVR 315 Neisseria meningitidi...
P50840 243 eveeKAN---YDQPltIFASDIDHRMVQIAKENAEEAGLGDLIQFKQMQVKDFT---TNl-eFgvIVGNPPYGERLGEKK 315 Bacillus subtilis sub...
Q57880 243 kikkEIVenkNIYK--IIGLDKNQKYLDGAKDNAKNAEVLDTIEFICGDATKLH--EKFNe-SdvIIANPPYGIRIGSKR 317 Methanocaldococcus ja...
O28105 257 ewelAFEpneVRLK--LYGMEKFRKHLVGAIRNAVNAGVADTIEFRQGDAT-----EMTGe-YdvIITNPPYGLRIHRKG 328 Archaeoglobus fulgidu...
Q9YEM1 227 ----------------VYCVDLNPRHTRGARLNAESARVGGRVEVYTWDARMLHelLGEDs-VdrIVSNPPYGIRLGDPV 289 Aeropyrum pernix
O26820 214 ------------------GADIDWRMVEGTRENLQHYGITDFEVIRS-DARDLR---LDEk-VdaIVTDPPYGISASTAG 270 Methanothermobacter t...
O29011 203 ------------------GIDFIEKIVRGCRVNLEYYGIEGSVLLGDAKNLPLR---DEs--VrgIATDYPYLRSTKAAG 259 Archaeoglobus fulgidu...
Q9YAV9 225 ------------------CGDLDWAMVRGGPLNLSRYCPPGIWFYSAWNAAKLP---LSSnsVdsIATDPPYGRSTTTGR 283 Aeropyrum pernix
Q9RTT7 247 ----------------LVGVDIDPVAVACARTNLRAAGKEVEVAQVDALHTGLP---SRs--FdlVISDLPWGDAIGSHQ 305 Deinococcus radiodurans
P97770 352 ----DNN---PLAV--NRAANNISSLLTKSQIKDGKTTWGLPIDAVQWDICNLP--LRTAs-VdiIVTDMPFGKRMGSKK 419 house mouse
3V8V_B 321 AL-IALHSLLGRIMKNQFGG---WNLSLFSASPDLLSCLQLR--ADKQYKAKNGPLDCVQKN 376 Escherichia coli K-12
Q55156 325 AL-GDFYQQIGDVLKQRFRG---WTAFVFSGNKALTKRIGLR--TSARFPVNNGGLPCTLLK 380 Synechocystis sp. PCC 6803 substr. Kazusa
P44524 320 AL-IALYSVFGQRLKKEFCG---WNVSVFSSESTLLDCLRMR--ASRQFKAKNGPLDCVQKN 375 Haemophilus influenzae Rd KW20
Q9K0V4 316 AL-QALYPQLGTWLKKHYAG---WLAAMFTGDREMPKFMCLS--PKRKIPLYNGNIDCRLfl 371 Neisseria meningitidis MC58
P50840 316 AV-EQMYKEMGQAFEP-LDT---WSVYMLTSNENFEEAYGRK--ATKKRKLFNGFIKTDYYQ 370 Bacillus subtilis subsp. subtilis str. 168
Q57880 318 SV-KKLYDEFLSSAKEIMHGs-sRLIVITAEDKMFKDAIAKN--NFEVKEEFNVMFGGLMTR 375 Methanocaldococcus jannaschii DSM 2661
O28105 329 AI-ERLYHSFARAAKRCMNQn-sRLVIITAEHRVFANAAEEA--GLQCTHERFVKYGGLLTK 386 Archaeoglobus fulgidus DSM 4304
Q9YEM1 290 DV-RILYREFMPSAARVLRSg-gRAAIITAETKALVAAARSS--GLRMAGARRVRHGDLWVD 347 Aeropyrum pernix
O26820 271 EKsEKLYREFLDSAHSNLAEg-gMICMAAPHYLDLESLIDERf-SIRERYSMRMHRSLTRVI 330 Methanothermobacter thermautotrophicus ...
O29011 260 TL-DELYSKTSEEFERVLKK---GGRAAIVTNIDVESFFSNF--EIEMKTEERVHGSLTRRI 315 Archaeoglobus fulgidus DSM 4304
Q9YAV9 284 MGyLSLTRAFLNTAVEVLRSe-gWIVYAGPTRMSPETLAEDAglRVVKVIEMFVHGSLTRSI 344 Aeropyrum pernix
Q9RTT7 306 SN-ETLYPAFLKEMHRLTSRr-gRLCLLTHELRLFERVMREQs-DWEAKELFQVYSGGHHPK 364 Deinococcus radiodurans
P97770 420 RN-WNLYPACLREMSRVCRPgtgRAVLLTQDKKCFTKALSGMghVWRKVHVVWVNIGGLHAA 480 house mouse
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