6G5I,3RE4,6FDN,1TQI


Conserved Protein Domain Family
RIO1

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pfam01163: RIO1 
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RIO1 family
This is a family of atypical serine kinases which are found in archaea, bacteria and eukaryotes. Activity of Rio1 is vital in Saccharomyces cerevisiae for the processing of ribosomal RNA, as well as for proper cell cycle progression and chromosome maintenance. The structure of RIO1 has been determined.
Statistics
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PSSM-Id: 366498
View PSSM: pfam01163
Aligned: 31 rows
Threshold Bit Score: 194.772
Threshold Setting Gi: 81856970
Created: 24-Apr-2019
Updated: 18-Jul-2019
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
6G5I_z   193 NVYHAsTANGESRAIKIYKTSILVFKDRDKYVSGEFRfrHGycKGNPRKMVKTWAEKEMRNLIRLNTAEIPCPEPIMLRS 272 human
O30245   105 AVFNCysEKFGECVVKFHKVGHTSFKKVKEKRDYGDL--------HFSVLAIRSARNEFRALQKLQGLA--VPKVYAWEG 174 Archaeoglobus fulgi...
Q980T1   107 LVYYGydFNDNKIIVKFHRVGTDSYKKVKFRKSQEKK--------SWLSITVENAKREFEALTCLSNEGGYVPKPLGVEY 178 Saccharolobus solfa...
Q9YBJ6   107 DVYVAvsPAGSKLTVKLHRAGRESFRKVRRHRSYALD--LR--PTSWLDVSKALAEREFKILVRLEEEGARIPSPVAWNR 182 Aeropyrum pernix
Q8U3U1   111 DVYVAitPQGEKVAIKFNRIGERTSARKAYYHSDVFA---DkhHKSWLYVSRLIAKKEHEALVLLSSF-AKVPKPIAWNR 186 Pyrococcus furiosus
Q9BVS4   108 DIYIVanEEGQQFALKLHRLGRTSFRNLKNKRDYHKHr----hNVSWLYLSRLSAMKEFAYMKALYERKFPVPKPIDYNR 183 human
ANM64490 106 DIFEVaqEDGTILAMKLHRLGRTSFRAVKSKRDYLRHr----sSFSWLYLSRLAALKEFAFMKALEEHDFPVPKAIDCNR 181 thale cress
Q9VBU2   108 NIYVVadEEGTPICLKLHRLGRTCFRNVKAKRDYHGRr----hKASWLYLSRISATREFAYMSALYDRGFPVPKPIDFNR 183 fruit fly
Q9HSL0   107 DVYEVq--sFRPMALKFHREGYTQFREVHRGRDYTSEk----eHTSWQYTARKAAEREYDALEALYPT-VNVPRPVDHNR 179 Halobacterium salin...
6FDN_A   108 DIYIVaNEEGQQFALKLHRLGRTSFRNLKNKRDYHKHr----hNVSWLYLSRLSAMKEFAYMKALYERKFPVPKPIDYNR 183 human
6G5I_z   273 HVLVMSFIGkDDMPAPLLKNVQl-sEsKARELYLQVIQYMRRMYQDARLVHADLSEFNMLYHG-G-GVYIIDVSQSVEHD 349 human
O30245   175 NAVLMELID--AKELYRVRVEN-----PDE-VLDMILEEVAKFY-HRGIVHGDLSQYNVLVSE-E-GIWIIDFPQSVEVG 243 Archaeoglobus fulgi...
Q980T1   179 NAVAMEYID--GIELYKIPVTNm-dL-NLDEILEKILQTMRIAYTICHITHGDLSPYNVLIDK-NgNPYLIDWPQATK-- 251 Saccharolobus solfa...
Q9YBJ6   183 HAVVQRYVE--GVLLADVRVLDt--E-AAASILRDVLETLRIAYTRVGVVHGDLSEYNVIATT-EgRGVVIDWPQYVYRD 256 Aeropyrum pernix
Q8U3U1   187 HAIVMEFID--GVELAELRDTDltkE-EAEEILGKVLDEYEKIV-KFGIVHGDMSEFNIVITK-DnDILIIDWAQYLTCA 261 Pyrococcus furiosus
Q9BVS4   184 HAVVMELIN--GYPLCQIHHVE-----DPASVYDEAME-LIVKLANHGLIHGDFNEFNLILDE-SdHITMIDFPQMVSTS 254 human
ANM64490 182 HCVIMSLVQ--GYPMVQVKQLQ-----NPETIFEKIIGI-VVRLAEHGLIHCDFNEFNIMIDD-EeKITMIDFPQMVSVS 252 thale cress
Q9VBU2   184 HCVLMDLVK--GWPMTQVHELL-----DAPQVYDDLMN-LIVRLGNSGVIHGDFNEFNLMVTD-AgKPILIDFPQMMSTS 254 fruit fly
Q9HSL0   180 HAIVMEKVS--GTELSNAKLNP---E-QASGVLDLILREVAAAY-REGYVHADVSEYNVFVDS-D-GVVLFDWPQATPTD 250 Halobacterium salin...
6FDN_A   184 HAVVMELI--NGYPLCQIHHV----E-DPASVYDEAM-ELIVKLANHGLIHGDFNEFNLILDEsD-HITMIDFPQMVSTS 254 human
6G5I_z   350 HPHALEFLRKDCANVNDFFMRHSVAv---MTVREL 381 human
O30245   244 EEGWREILERDVRNIITYFSRTYRTe---KDINSA 275 Archaeoglobus fulgidus DSM 4304
Q980T1   252 ---SEERLEKDLSNLIIFFRKKGID----VDTRKI 279 Saccharolobus solfataricus
Q9YBJ6   257 EPHALELLRRDVEYILKYFRRRAGLk---VELASA 288 Aeropyrum pernix
Q8U3U1   262 NPESLGLLKRDISVLLNAFRRRWGVk---RDFEee 293 Pyrococcus furiosus
Q9BVS4   255 HPNAEWYFDRDVKCIKDFFMKRFSYe--sELFPTF 287 human
ANM64490 253 HRNAQMYFDRDIECIFKFFRKRFNMs---FHEdkg 284 thale cress
Q9VBU2   255 HENAEFFFERDVNCVREMFRRKFGYe--sEDYPKF 287 fruit fly
Q9HSL0   251 HENARELLARDVENIVQYFRQKYPSdvpaVDHDAV 285 Halobacterium salinarum
6FDN_A   255 HPNAEWYFDRDVKCIKDFFMKRFSYeselfptfkd 289 human
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