Conserved Protein Domain Family
MHC_II_alpha

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pfam00993: MHC_II_alpha 
Click on image for an interactive view with Cn3D
Class II histocompatibility antigen, alpha domain
Statistics
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PSSM-Id: 307229
View PSSM: pfam00993
Aligned: 88 rows
Threshold Bit Score: 64.1082
Threshold Setting Gi: 597767636
Created: 14-Jul-2016
Updated: 4-Aug-2016
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

pfam00993 is a member of the superfamily cl03058.
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
1R5V_A         2 EHTIIQ-AEfyllpDKRGEFMFDFDGDEIFHVDIEKSETIWRLEEFAK-FASfeAQGALANIAV--------DKANLDVM 71
gi 81908601   41 NHTFRH-TLfcqdgIPNIGLSETYDEDELFSFDFSQNTRVPRLPDFAEwAQG---QGDASAIAF--------DKSFCEML 108
gi 512969512  41 NHTFRH-TVfcqegTPSIGLSESYDEDLLFSFDFSKNTRVPRLPDFAD-WAQ--DQSDAPAIAF--------DKQFCEIM 108
gi 625262942  42 NHTFRH-TVfcqdgNPSIGLSESYDEDQLF-YDFSQNTRVPRLPDFADwAQE---QGDASAISF--------DKEFCNML 108
gi 511902242  41 NHTFQH-TMycqnwNPSIGLSEAYDGDQLFSFDFSQNTRVPRLPEFADwAQK---PGDTSTIFF--------DKTFCQSM 108
gi 731511189  41 NHTFLH-TMycqngTPSLGLSEAYDEDQLFSFDFSQNSRVPRLPEFADwAKD---QGDVSAISF--------DKEFCQSM 108
gi 221042088  33 NHTFLH-TVycqdgSPSVGLSEAYDEDQLFFFDFSQNTRVPRLPEFADwAQE---QGDAPAILF--------DKEFCEWM 100
gi 914899366  41 NHTFRH-TVfcqdgSPSIGLTETYDEDLLFSFDFSRNTRVPRLPEFADwAQD---QRDASAIVF--------DKGFCEAM 108
gi 351703551  92 NHTFRH-TVfcqegTPSIGLSESYDEDLLFSFDFSKNTRVPRLPDFADwAQD---QSDAPAIAF--------DKQFCEMM 159
gi 125824743  17 KDYHKYgLIgacgdADQEDFIVQFDDEQLAHVDFKEQKDVITLPEFAG-------QAVLPPIYVdakraefnCKAYLAVL 89
                         90
                 ....*....|
1R5V_A        72 KERSNNTPDA 81
gi 81908601  109 MREVSPKLEG 118
gi 512969512 109 VQQLDPVLDG 118
gi 625262942 109 IQEIGPQLEG 118
gi 511902242 109 IQEIGPHLEG 118
gi 731511189 109 IQDIGPQFDG 118
gi 221042088 101 IQQIGPKLDG 110
gi 914899366 109 IEKIGPQLEG 118
gi 351703551 160 VQQLDPVLDG 169
gi 125824743  90 REVYASSPEV 99
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