3CM6,2P1J,2XRI,4XR7,2IGI,1J9A,4JS4,1J54


Conserved Protein Domain Family
RNase_T

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pfam00929: RNase_T 
Click on image for an interactive view with Cn3D
Exonuclease
This family includes a variety of exonuclease proteins, such as ribonuclease T and the epsilon subunit of DNA polymerase III.;
Statistics
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PSSM-Id: 279297
View PSSM: pfam00929
Aligned: 41 rows
Threshold Bit Score: 78.1556
Threshold Setting Gi: 75090810
Created: 12-Jul-2016
Updated: 4-Aug-2016
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
3CM6_A   22 LILDFETTSDAA------------N-QDYPCEVIQFAIVAYDVpnd----kiREDISFNKYVKPVLNrtLTKNCVDFTGI 84   Caenorhabditis elegans
Q09798  860 VGIDSEFVALQQeetevrsdgtksTiKPSKLSLARVSVLRGEGp-------nKGLPFIDDYVATDDK--VTDYLTEYSGI 930  Schizosaccharomyces...
4XR7_A  568 VAIDAEFVSLQSelceidhqgirsIiRPKRTALARISIIRGEEge------lYGVPFVDDYVVNTNH--IEDYLTRYSGI 639  baker's yeast
O64348   22 VVIDTETTGLGe--------------YAEIIEIAIINMRGEVLld------tLVKPTKPIPPEVTEInhITNEMVASAPA 81   Enterobacteria phag...
O94626   81 VWIDCEMTGLEVg-------------KHVLMEVAAIITDGNLRp-------vEEKFDAVIKLDEKQLseMNDWCIEQHGK 140  Schizosaccharomyces...
P9WIU1    6 VWIDCEMTGLDLg-------------SDKLIEIAALVTDADLNi-------lGDGVDVVMHADDAALsgMIDVVAEMHSR 65   Mycobacterium tuber...
Q17819   16 IWIDCEMTGLDVe-------------KQTLCEIALIVTDSELNt-------iATGPDIVIHQPKEVLdnMEEWPRNTFHE 75   Caenorhabditis elegans
2IGI_A    8 IWIDLEMTGLDPe-------------RDRIIEIATLVTDANLNi-------lAEGPTIAVHQSDEQLalMDDWNVRTHTA 67   Escherichia coli K-12
1J9A_A   11 IWIDLEXTGLDPe-------------KERIIEIATIVTDKNLNi-------lAEGPVLAVHQSDELLnkXNDWCQKTHSE 70   Haemophilus influenzae
P54964   56 VWIDCEMTGLDHv-------------NDRIIEICCIITDGHLApvkaadgqgDSHYESVIHYGPEVMnkMNEWCIEHHGN 122  Saccharomyces cerev...
3CM6_A   85 PQRSIDTADTFDV--VYEQFQQWLItLGLEEG---KFAFVCDSRQDLWRIAQYqmklsniQMPAFFRQYINLYKIFTNEM 159  Caenorhabditis elegans
Q09798  931 HPGDLDPDRSPYN--VVP-LKVAYKkLRLLVNa--gCIFVGHGLQKDFRIINLlv-----pPEQVVDTVDLFFLSSRQRK 1000 Schizosaccharomyces...
4XR7_A  640 LPGDLDPEKSTK---RLVRRNVVYRkVWLLMQl--gCVFVGHGLNNDFKHINInv-----pRNQIRDTAIYFLQG--KRY 707  baker's yeast
O64348   82 WCDVFPKVLAIISkhKWLAWNSGFDaRMLEQTclnTIFLNKNAYYVTAMVSRIhtshidaKAVYDTWYGEY-DAKHQAFK 160  Enterobacteria phag...
O94626  141 SGLTERCRQSNLT--VKDVENQLLAyIKKYIPkkrEALIAGNSVHADVRFLSVem----pKIIEHLHYRIIDVSTIKELA 214  Schizosaccharomyces...
P9WIU1   66 SGLIDEVKASTVD--LATAEAMVLDyINEHVKqpkTAPLAGNSIATDRAFIARdm----pTLDSFLHYRMIDVSSIKELC 139  Mycobacterium tuber...
Q17819   76 NGLMEKIIASKYS--MADAENEVIDfLKLHALp-gKSPIAGNSIYMDRLFIKKym----pKLDKFAHYRCIDVSTIKGLV 148  Caenorhabditis elegans
2IGI_A   68 SGLVERVKASTMG--DREAELATLEfLKQWVPa-gKSPICGNSIGQDRRFLFKym----pELEAYFHYRYLDVSTLKELA 140  Escherichia coli K-12
1J9A_A   71 NGLIERIKASKLT--ERAAELQTLDfLKKWVPk-gASPICGNSIAQDKRFLVKyx----pDLADYFHYRHLDVSTLKELA 143  Haemophilus influenzae
P54964  123 SGLTAKVLASEKT--LAQVEDELLEyIQRYIPdknVGVLAGNSVHMDRLFMVRef----pKVIDHLFYRIVDVSSIMEVA 196  Saccharomyces cerev...
3CM6_A  160 DrmgpkelsatTNIGKMNEYYDLPTIGRa-HDAMDDCLNIATIL 202  Caenorhabditis elegans
Q09798 1001 L-----------SLKFLAWYLLDEEIQLteHDSIEDALTALKLY 1033 Schizosaccharomyces pombe 972h-
4XR7_A  708 L-----------SLRYLAYVLLGMNIQEgnHDSIEDAHTALILY 740  baker's yeast
O64348  161 Rq--------sLTIAAARHGVLLEGa----HRALADCKMVLAVL 192  Enterobacteria phage N15
O94626  215 K----------RWCPDIPA-YDKKGD----HRALSDILESIGEL 243  Schizosaccharomyces pombe 972h-
P9WIU1  140 R----------RWYPRIYFGQPPKGLT---HRALADIHESIREl 170  Mycobacterium tuberculosis H37Rv
Q17819  149 Q----------RWYPDYKH--PKKQCT---HRAFDDIMESIAEL 177  Caenorhabditis elegans
2IGI_A  141 R----------RWKPEILD--GFTKQGT--HQAMDDIRESVAEL 170  Escherichia coli K-12
1J9A_A  144 A----------RWKPEILEG-FKKENT---HLALDDIRESIKEL 173  Haemophilus influenzae
P54964  197 R----------RHNPALQARNPKKEAA---HTAYSDIKESIAQL 227  Saccharomyces cerevisiae S288c
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