3VR8,2BS4,1KNP


Conserved Protein Domain Family
FAD_binding_2

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pfam00890: FAD_binding_2 
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FAD binding domain
This family includes members that bind FAD. This family includes the flavoprotein subunits from succinate and fumarate dehydrogenase, aspartate oxidase and the alpha subunit of adenylylsulphate reductase.
Statistics
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Aligned: 62 rows
Threshold Bit Score: 154.753
Threshold Setting Gi: 46397432
Created: 11-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
3VR8_E  43 DVVIIGAGGAGLRAAMGLGEAGFKTAVVTKMFPtrsHTTAAQGGINAAL-GSM--N-P-DDWKWHFYDTAKGSDWLG-DQ 116 pig roundworm
Q7MF00   5 DIAVIGGGIAGYCAALNAIEAGKKTVLISQGQS---ALHFSSGSIDVMAkTPSg-----E-RVEAPFSAMASLPQQHpEH 75  Vibrio vulnificus YJ016
Q7VM49   4 DVVIIGGGLAGLTCGIALQKQGKQCAIINNGQA---AIDFSSGSMDLLScLPSg-----Q-KVHVFCEAFSELSQQApEH 74  [Haemophilus] ducreyi...
P43800   4 DVAIIGGGLAGLTCAIALQQRGKRCVIINNGQA---AIDFASGSLDLLSrMPSttYgEnR-AVENLKENITALRNELpAH 79  Haemophilus influenza...
Q9CL07   4 DVVIIGGGLAGLTCGIALQTQGKQCVIINNGQA---AIDFSSGSLDLLGqLPSg-----R-QIQHFEQNYTALYQQAaQH 74  Pasteurella multocida...
Q83ML0   4 DTVIMGGGLAGLLCGLQLQKHGLRCAIVTRGQS---ALHFSSGSLDLLShLPDg-----Q-PVADIHSGLESLRQQApAH 74  Shigella flexneri
Q8ZAH6   4 DVIIIGGGLAGLACGIRLAEQGKYCAIVSSGQN---ALHFSSGSLDLLAkLPDg-----Q-AVSQPLSALSALAELApEH 74  Yersinia pestis
Q6CZI7   4 DVVIIGGGLAGLTCGIRLAEQGKRCAIVSAGQN---ALHFSSGALDLLShLPDg-----Q-PVSQPLDALDELARQApHH 74  Pectobacterium atrose...
Q9HNS3   6 EVLVIGGGLAGITSALAAADAGADTRLVSYKQS---TLRNASGLVDVLGyTPSg-----DGPVVDPFDAIPSLPd---AH 74  Halobacterium salinar...
Q6A5L1  20 HVVVIGSGLAGLTTALRLRRGGARVTLVTKGVG---GLQLGQGTIDILGyTPD--------RVEKPYQAVQEFASQHpAH 88  Cutibacterium acnes
3VR8_E 117 NAMHY-LTRNAVEAVTELENF----GMPFSRtp--egKIYQRSFGGQSNNygkggvaKRTCC-VADR------TGHSMLH 182 pig roundworm
Q7MF00  76 PYSKM-SPNFVRQSLYWLVDQlkeqGLPLHCqqdesnHHRITPLGTLKAT-------WLSQPfVYQHrq--nvAFKRLLF 145 Vibrio vulnificus YJ016
Q7VM49  75 PYCLL-GQHQVVAKVQQFEQFmq--eLGLVGshk-qnHLRVTPLGGLRHT-------WLSPKsVPVIaenehfPYRQIAI 143 [Haemophilus] ducreyi...
P43800  80 PYSLL-GAEKVLAKAQDFERLanelHLDLIGste-knHWRVTGLGSLRGA-------WLSPNsVPTVqgnepfPHKRIAV 150 Haemophilus influenza...
Q9CL07  75 PYALV-GKDKVIEKARQFEQLaqtlNLGLVGtcd-knHFRVTPLGGLRPT-------WLSPNsVPIVtneemfPHRKIAV 145 Pasteurella multocida...
Q83ML0  75 PYSLL-GPQRVLDLACQAQALiaesGAQLQGsve-laHQRITPLGTLRAT-------WLSSPeVPVWp----lPAKKICV 141 Shigella flexneri
Q8ZAH6  75 PYSKMrNITQLDELVQEAEALlrrcGLDIVGssa-enHLRLTPLGSCRPT-------WLSLAdIPVAplngplPWQRVAV 146 Yersinia pestis
Q6CZI7  75 PYSRM-GAAAVAALLPQVEALlersNISLLGnhq-qnHWRMTPLGKFRAC-------WLSPAdGVTRgladshFGDNPLI 145 Pectobacterium atrose...
Q9HNS3  75 PYRTV-GVDTVRDAMAFFDAH----APRYQGhhtdanALVPTHGGTVKPT-------ARYPAsAAAgl---asDDRDTLL 139 Halobacterium salinar...
Q6A5L1  89 PYAKI-GVEAVKEGIDFLREVvgdsYLLGDGea---tINVPTAVGAIRPT-------ALVPPsMINgn---lkDGDKVVV 154 Cutibacterium acnes
3VR8_E 183 TLYGNSlrchCTFFIEYFALDLLMd--KG----RCVGVIALc------lEDGTIHRFRSK-RTIVATGGYGR-------- 241 pig roundworm
Q7MF00 146 VAVDGY----RDFQPLLAKDNLKKh--PDfqhcEIGEIQVTipgcealrRNPNELRSIDIaRLLKQPQAFNslchq---- 215 Vibrio vulnificus YJ016
Q7VM49 144 LGIEGY----HDFQPQILVDNLKQn--AAfshcDFSIGYLNipeldylrQNAREFRSVNIaQLLEHKLAFEdlvqe---- 213 [Haemophilus] ducreyi...
P43800 151 LGIEGY----HDFQPQLLAANLVLn--PQfehcEVTSGFLNipqldelrKNAREFRSVNIsQLLEHKLAFKdlvke---- 220 Haemophilus influenza...
Q9CL07 146 LGIEGY----HDFQPQLLAENLVQh--AQfahcEVTTGYLNipeldhlrHQSREFRSVNIaQLLEHKLAFSdlvre---- 215 Pasteurella multocida...
Q83ML0 142 VGISGL----MDFQAHLAAASL------ReldlSVETAEIElpeldvlrNNATEFRAVNIaRFLDNEENWPlllda---- 207 Shigella flexneri
Q8ZAH6 147 IGIEGF----LDFQPQMVASAL------QdqgiDATADYLHlpaldrlrDNPSEFRAVNIaRILDLPENRQplade---- 212 Yersinia pestis
Q6CZI7 146 AGIEGF----LDFQSRIVAGTL------QtqgiAARSDELKlpvldrlrQNPSEFRAVNIaRLLDRPENRSalvee---- 211 Pectobacterium atrose...
Q9HNS3 140 VGFETL----PDFNADHAAAHLe----SAgvpfDVRGVTVPfpg--dlrAGAKVTR---YaGLLDANPQVSVdgterplr 206 Halobacterium salinar...
Q6A5L1 155 IGLAQY----KDFHAGLIAQNINRttlPGgghaSARAVVVDfe----prEGEYDATGLAIaRSLDDARTRRmlaeg---- 222 Cutibacterium acnes
3VR8_E 242 -----------AYFSCTTAHMNTGDGTALATRAGIA-LED--LEFIQFHPTGIY----GVGCliteGSRGEGGFLVN-SE 302 pig roundworm
Q7MF00 216 ------lmkhaTQEDLVIMPAIMGNGDGLVLLQQLRrQTNltLHEVPTMPPSLLgiriEEALq--kRFLKQGGVLLKgDQ 287 Vibrio vulnificus YJ016
Q7VM49 214 ------ikqaaGNAQAVFLLACFGLDDQ-RFFDSLKqATAlaLFELPTLPPSLIgirqYRTLr--dQFEKLGGLLLNgDR 284 [Haemophilus] ducreyi...
P43800 221 ------iiesaQGAEAVFLPACFGLENQ-EFMTALRdATKlaLFELPTLPPSLLgmrqRIQLr--hKFESLGGLMINgDS 291 Haemophilus influenza...
Q9CL07 216 ------ireavNGASAVFLPACFGLETQ-EFFSALKqATQleLFELPTLPPSLLgmrqHKQLt--qHFKQLGGLMMNgDK 286 Pasteurella multocida...
Q83ML0 208 ------lipvaNTCEMILMPACFGLADD-KLWRWLNeKLPcsLMLLPTLPPSVLgirlQNQLq--rQFVRQGGVWMPgDE 278 Shigella flexneri
Q8ZAH6 213 ------lsrlsSTAEMILLPACIGLDKS-APLDALRaVVGkpIQLLPTLPPSLLgmrlHQALr--hRFQQLGGLVMPgDA 283 Yersinia pestis
Q6CZI7 212 ------lsllaNGNDAIIMPACLGLDSP-EIVSELAdALGkpVLLLPTLPPSVLglrlHQALs--qRFRQLGGMVMPgDR 282 Pectobacterium atrose...
Q9HNS3 207 lalatrvadaaADADRVGFPAVLGDDDPAGVRDALAdHLGaaVFEVPMGPPSLPglrlSDHLf--gALEAAGVRIETgNP 284 Halobacterium salinar...
Q6A5L1 223 ------lrgfvNPGEIVALPAVLGIDNHSEVLADFKkILGaeVFEIASLPPCVPgmrlNNKLv--aTAKNERVDYVLgSK 294 Cutibacterium acnes
3VR8_E 303 GERfmeryapkaKDLASRDVVSRAET-IEIMEGRGvgpekDHiYLQLHH-LPAEQLHQRLPGISETAKIFAG------VD 374 pig roundworm
Q7MF00 288 VLS---------GEWDAQGHLVSISTrNLGDIPLH-----ANaYILASGsYFSQGLKASLDK-IVEPIFGLDm-----vA 347 Vibrio vulnificus YJ016
Q7VM49 285 AVR---------AEF-DGDRVARIFTtLHQEESIN-----AAhFVLASGsFFSNGLVAEFER-VKEPIFDLDiignkaFI 348 [Haemophilus] ducreyi...
P43800 292 ALN---------ATF-EGNQVRCINTrLLEDEEIT-----ADnFVLASGsFFSKGLISEFDK-IYEPVFESDiigvegFN 355 Haemophilus influenza...
Q9CL07 287 VIA---------ADV-HHQRVTQVYTqLHQEIPIQ-----AKdVVLASGsFFSKGLVAEFEK-IREPIFALDlvendrFN 350 Pasteurella multocida...
Q83ML0 279 VKK---------VTC-KNGVVNEIWTrNHADIPLR-----PRfAVLASGsFFSGGLVAERNG-IRETILGLDv-----lQ 337 Shigella flexneri
Q8ZAH6 284 VLR---------AEL-VDNRITGLYSrNHGDIPLR-----AAqMVLASGsFFSNGLVATFDK-IYEPILDLDi-----lS 342 Yersinia pestis
Q6CZI7 283 AVR---------ASL-SSQEI-AVHShHHRDIPLR-----AKhAVLASGsFFSNGLVTQFDR-VTEPVFGLDv-----rF 340 Pectobacterium atrose...
Q9HNS3 285 VVD---------ADTTAGGVETVYVEkNGARIPNS-----ADeYVLATGgLVGKGIDSDRDA-VYEPIFDCRi-----aH 344 Halobacterium salinar...
Q6A5L1 295 VTG---------CTVADGKVVSVTVGtAGAGKEIK-----ADaVVLAGGgFESGALKLDSHGHLHETILDLPvtmpegVK 360 Cutibacterium acnes
3VR8_E 375 VTKEpi----pVIPTV--HYNMGGIPTNYKAQVikytKEGGDKIVPGLYACGECAcHSVHGANRLGANSL 438 pig roundworm
Q7MF00 348 KPHRrqwrndqFFSASahPFMAFGVETDAMFRP-----SLNGQVCQNLYCCGSVL-SGYDPVFEGSGGGV 411 Vibrio vulnificus YJ016
Q7VM49 349 NSERvswtdkrFAAAQ--PYQSAGVAINHHCQV-----YKNGHLIPNLYAIGNVI-GGFWGIEQGCASGV 410 [Haemophilus] ducreyi 35000HP
P43800 356 NKDRftwtahrFAHPQ--PYQSAGVAINAQCQV-----KKCGQFLTNLYAVGNVI-GGFNALELGCGSGV 417 Haemophilus influenzae Rd KW20
Q9CL07 351 LQDRmtwthsrFSAPQ--PYQQTGVVIDEHCRA-----RKSGQFFENLYAIGNIV-GGFNGIELGCGSGV 412 Pasteurella multocida subsp. mu...
Q83ML0 338 TATRgewykgdFFAPQ--PWQQFGVTTDETLRP-----SQAGQTIENLFAIGSVL-GGFDPIAQGCGGGV 399 Shigella flexneri
Q8ZAH6 343 LPHRadwshsnLFAPQ--PYLQFGVNTDNHLRP-----LRGGVALENLHAIGAVL-GGYDPLQQGCGAGV 404 Yersinia pestis
Q6CZI7 341 AEQRegwsqqdVFAPQ--PYMQFGAIVDEHLHP-----RIAGETVNNLYAIGAVL-EGFDPIVQGCGAGV 402 Pectobacterium atrosepticum SCR...
Q9HNS3 345 SDDRyawfdddAFGDH--AFAQFGVRTDDTLRPr---DDDGAAAHANLRAAGAVL-GGYNFAAEHSGSGV 408 Halobacterium salinarum NRC-1
Q6A5L1 361 EEDLihg--dyWGSPQ--PLFLCGVEVDETMLV----TYQGKPVHSNVYAAGGVI-AGATRWQEKSGEGI 421 Cutibacterium acnes
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