2WP8


Conserved Protein Domain Family
RNB

?
pfam00773: RNB 
Click on image for an interactive view with Cn3D
RNB domain
This domain is the catalytic domain of ribonuclease II.
Statistics
?
Aligned: 60 rows
Threshold Bit Score: 153.207
Threshold Setting Gi: 74852807
Created: 23-Apr-2019
Updated: 18-Jul-2019
Structure
?
Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection:
2WP8_J  507 RKDLRDKLICSIDP--PGCVDI-----NDALHAKKLP-------NG--NWEVGVHIADVTHFVKPGTALDAEGAARGTSV 570  baker's yeast
Q2JH83  252 RRDLRDWFCITLEP--LDLQHPhglepNVAVSLQRQE-------ND--HWLLGIHIADVAHWLDPDHPLEQEAQQRTATV 320  Synechococcus sp. J...
Q8YXH3  245 klDLRNLFTFTITGinSDTKVI-----ENAISLEKTI-------AG--NWQLGFHIADVSHYVQPDEPLDREAIKRGRSV 310  Nostoc sp. PCC 7120
Q46363  245 RTWITAKLQLVTFG--DGPRGEtlpwqEVALSLE----------SQanQWQVGIHITDIAHYIAEDSLLDQLARKRGTTV 312  Synechocystis sp. P...
Q31LX8  247 RLDLRSVFTVAIAA--DDSRPL-----DVALSLQPGE-------SG--GWQVMVHTVEVAPYLPLQSDLDLEAQRHGIDL 310  Synechococcus elong...
Q8DHS2  247 RQDLRELVTITLVA--PGQEP------QVAFSL---Dg------LGpdLWQLGIHISDVGGLLPRDELLDRTARRQGMSL 309  Synechococcus elong...
Q7V7I0  239 RQDLSSQPALLLRS--WQVSDA-----------PPLPavyvephAG--GTRLWIHAPAVAERLTIGNNLDLWLRDRAEAL 303  Prochlorococcus mar...
Q7VBV4  238 RNNLESQPCILFKS--WSSKNC-----------PLLPalysepsNG--GMTLWIHIPTIGERLNYGSKLDEWIRNRSNSI 302  Prochlorococcus mar...
Q4WSW3  759 RRDFRSETTFTIDP--SGAIEL-----DNAYHIKPLA-------DG--KVEIGIHVSDIAHFVKANSLVDREAKKRGTAV 822  Aspergillus fumigatus
P24276  692 FTDTNEYNIFAISE--LGWVS------EFALHVRNNG-------NG--TLELGCHVVDVTSHIEEGSSVDRRARKRSSAV 754  Saccharomyces cerev...
2WP8_J  571 YLVDKRIDMLPMLLGTDLCSLKPYVDRFAFSVIWELDDS-ANI-VNVNFMKSVIRSREAFSYEQAQLRIddkt------- 641  baker's yeast
Q2JH83  321 YLDTMVLPLFPPEVHNRL-ALLPQQERLAYSLLVTLDPE-GVV-QNFEIYPSLVQSRAHLSYGQVQALLattadlg---- 393  Synechococcus sp. J...
Q8YXH3  311 YLGDLVLSMLPDTVADR-ASFVTGSDRLALSFLITISSQlGEV-LEWEIQPSVINVDNNVSKQQAEAILqgaat------ 382  Nostoc sp. PCC 7120
Q46363  313 YLEEQICPLFPEGLIGR-CSLIPDEDRLALSFFLTVDDR-GEV-TGFEYHSSVVKVDHQLDFSEVQTALad--------- 380  Synechocystis sp. P...
Q31LX8  311 RLGETALPFLPPVLTQGVGRFAVGEDRRAVSLLIRVDAT-GAV-QDYELQPSLVQLDQVLSPAEATDLLadsk------- 381  Synechococcus elong...
Q8DHS2  310 ATPELSLPLLPQELET--LRLLPGGDRAAISLLIVLNTA-GEV-QSYRIYRSCIRVDACVTSEQVAATLal--------- 376  Synechococcus elong...
Q7V7I0  304 CLGEVWHPLLGQILSKA-CSFKVGEINDAVSVALDISAD-GEV-TNWHFSLSSIKPVAEIGPKTLTALSnrkpkartvpa 380  Prochlorococcus mar...
Q7VBV4  303 CFGEEWQCFLGDKLNKE-AGFEIGKSNSAITLELFIDKN-GKC-QSWEFYLSTIKPVAKVSQKNLDDILkrkkrsrivpa 379  Prochlorococcus mar...
Q4WSW3  823 YLMDRLVNMLPRRVSTELCSLLPEQDRLTVSVVFTANPEtGAVdDDVWIGKSIIKSAGRLSYDEVNSVIkgetn------ 896  Aspergillus fumigatus
P24276  755 FMPQKLVNLLPQSFNDEL-SLAPGKESATLSVVYTLDSStLRI-KSTWVGESTISPSNILSLEQLDEKLst--------- 823  Saccharomyces cerev...
2WP8_J  642 ---qndELTMGMR--------ALLKLSVKLKQKRLEAGALNL-A---SPEVKVHMDSETs-------DPNE---VEIKKL 696  baker's yeast
Q2JH83  394 pdeevpELMALLQ--------NLLRLSQILRAKRHQAGGFDL------PLLDLLTPHSAdes--gygP------LLISDR 451  Synechococcus sp. J...
Q8YXH3  383 -kkdspQIIERLQ--------NLTTIGQAIKESRLARGSLQLnL---PSNQNPYYDE----------GSLG---AVLVND 437  Nostoc sp. PCC 7120
Q46363  381 ----ieSVSGELKpyggllqeLFFQICPLIKSQRLQRGSFNLqT----ETASPRLDE----------GRLG---VIMTQE 439  Synechocystis sp. P...
Q31LX8  382 ---akgEGIKALK--------ELQTIADLWRTQRRERGGFEL-------TVTPAIGNDEg----------A---LGVISR 430  Synechococcus elong...
Q8DHS2  377 ----gdSSGDWLR--------ALIHLANAVSQRRQARGSIEV-------------------------TPAEalrLAYADE 419  Synechococcus elong...
Q7V7I0  381 alkpvkDHLAQLE--------TLIFCARTLQMGEQASGSIEL-Dl-aVPELQCLGDLRWadpdsyhhQ------WALPLD 444  Prochlorococcus mar...
Q7VBV4  380 slkllkDYINNIE--------DLLYISKIINENLIKAGLIQL-Dl-pVPVIENLEDLDKtvpggefnG------WSDTYK 443  Prochlorococcus mar...
Q4WSW3  897 -vsvagISANIIQ--------TLNTITRKFREARFGN---RV-SnppPLRLLYQLDD-En-------VPVE---RNIFDS 952  Aspergillus fumigatus
P24276  824 -----gSPTSYLS--------TVQEIARSFYARRINDPEATLlP---TLSLLESLDD-Ek-------VKVD---LNILDR 876  Saccharomyces cerev...
2WP8_J  697 LA-TNSLV-------EEFMLLANISVARKI-YdAFPQTAMLRRHAAPPSTNFEILNEMLNtrknms-----islessKAL 762  baker's yeast
Q2JH83  452 LG-AHALM-------TEILLLANQILGHHL-R-QLGIPSLARVQPAPAAEALQSFLRLANamkldlnl-qdpavvtlADW 520  Synechococcus sp. J...
Q8YXH3  438 SP-VRSLL-------MELVLLVNELIATHL-S-ALGIPAIWRTQGTPDSEDVQEMLKLAInlgvelal-epevdiepLDY 506  Nostoc sp. PCC 7120
Q46363  440 TLpIRSLL-------AELMVVLQREVALQL-Q-ALGIPGLYCGQVAPEGEDLTDIVKLAGnldlgvki-dlegdiipQHY 509  Synechocystis sp. P...
Q31LX8  431 SPaIAGAV-------QEILIQANRLVTEHL-Q-ALELPVLYVGQRSPDLGSIQDAQRLAAglglaievdenetelnrLAL 501  Synechococcus elong...
Q8DHS2  420 GL-APAIFlpkvtpwTSLVILANELLGRHL-A-KLGVPALYRTQPVPELYGVQDFLKLCQnlnlplsl-dhpsqvtpRDY 495  Synechococcus elong...
Q7V7I0  445 QTdPQSVL-------SPMIRAAHRAWAQHA-Q-NLQLPGLVIEASEADNNTLNDVAKSALaldialel-deegrpaaTEL 514  Prochlorococcus mar...
Q7VBV4  444 DKdPQSII-------SVFTKYANIILKDHF-I-SYNISFIALKFKQPDNIQLNDVIKSALvldtkinv-neegiisfKDL 513  Prochlorococcus mar...
Q4WSW3  953 TD-ARELV-------EELRHKANFFVARKLvS-AMPDKAFLRRQPSPNSRRLHSFIDRMNrlgydf------dpsssgTL 1017 Aspergillus fumigatus
P24276  877 TL-GFVVI-------NEIKRKVNSTVAEKIyT-KLGDLALLRRQMQPIATKMASFRKKIQnfgynf------dtntadEL 941  Saccharomyces cerev...
2WP8_J  763 ADSLDRCvdpEDPY-----FNTLVRIMSTRCMMAAQYFYSG------AysypdfRHYGLAVDI-Y--------------- 815  baker's yeast
Q2JH83  521 QRICARI---TAPDvlasgASPALVAQMLATLPPVEYRLQPle--eqL------GHFGLGLKEpY--------------- 574  Synechococcus sp. J...
Q8YXH3  507 QQLTRAF---AESP-----SEQVLTYLLQDTLKPAVYSTTK------A------SHFGLALLQ-Y--------------- 550  Nostoc sp. PCC 7120
Q46363  510 HHLSQGF---ESLP-----AKAVLNHLLANTLKIEKYFSHP------A------PHFALAYDSgY--------------- 554  Synechocystis sp. P...
Q31LX8  502 QQLSDAT---QTSE-----LASLLDHLLLQTFKPSFYSTLA------V------PHFSLGLET-Y--------------- 545  Synechococcus elong...
Q8DHS2  496 QRFMAQL---ATSD-----LAALLQELLLDKLKPASDSPVV------L------THFGLATAEgY--------------- 540  Synechococcus elong...
Q7V7I0  515 AKAFSTT---ACRR--------VLDQQLRHALPETLLR------------------LGINDSQ-Kengniesdhedtktk 564  Prochlorococcus mar...
Q7VBV4  514 ILSLKES---PNKR--------LIEKIISNTILDKYYS------------------IPTSNSD-Dlglskedst---nli 560  Prochlorococcus mar...
Q4WSW3 1018 QSSLCKV---QDDD-----LRKGMETVLLKAMQRAKYYVAStvqdeqR------HHYTLNLPV-Y--------------- 1067 Aspergillus fumigatus
P24276  942 IKGVLKI---KDDD-----VRVGIEILLFKTMPRARYFIAGkvdpdqY------GHYALNLPI-Y--------------- 991  Saccharomyces cerev...
2WP8_J  816 -----THFTSPIRRYCDVVAHRQLAGAI 838  baker's yeast
Q2JH83  575 -----ATFTAPLRRYADLLNLRALHLAL 597  Synechococcus sp. JA-2-3B'a(2-13)
Q8YXH3  551 -----THFTAPLRRYPDLLMQRVYYQLL 573  Nostoc sp. PCC 7120
Q46363  555 -----THCVSPAQRYGDLVIQRLLKLVL 577  Synechocystis sp. PCC 6803 substr. Kazusa
Q31LX8  546 -----GHFVAPSQRYADLWLQRVILALF 568  Synechococcus elongatus PCC 7942
Q8DHS2  541 -----GHFCSPLQRYTDIVNQRILHLLL 563  Synechococcus elongatus
Q7V7I0  565 dsnlqSPWCCPTIHYTDLVNQEIIVTLL 592  Prochlorococcus marinus str. MIT 9313
Q7VBV4  561 sadieAPWSSPGMNYADVINQFILLKLL 588  Prochlorococcus marinus
Q4WSW3 1068 -----THFTNPSRRYADIIVHRQLEAVL 1090 Aspergillus fumigatus
P24276  992 -----THFTAPMRRYADHVVHRQLKAVI 1014 Saccharomyces cerevisiae S288C
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap