5W7C,5TIC,1PP4,3MIL


Conserved Protein Domain Family
Lipase_GDSL

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pfam00657: Lipase_GDSL 
GDSL-like Lipase/Acylhydrolase
Statistics
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PSSM-Id: 459892
Aligned: 67 rows
Threshold Bit Score: 37.9375
Created: 21-Mar-2022
Updated: 17-Oct-2022
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
5W7C_D         105 IILLGDA-------AGAHFHispewitas---------qmslnsfiNLPTaltneldwpqlsgATGFL-DSTVGIKeksi 167  human
jgi:Fjoh_0246   74 IVHIGDShiqgdlmTNKIRKllqqkfgnagrgfvfpyqlaktngsyNERFscnriw--esyrnIYPVR-NYPVGLSgigl 150 
Q9RDP5          66 VAAVGDS-------ITRGFDaca--------------------vlsDCPEvswat----gssaKVDSLaVRLLGKAd--- 111  Streptomyces...
Q9N4P5         105 VGAMGDS-------LASGRGlwpftdvef--------rgaafpiggDANMdglvt----ipniLSQFG-SNLEGIShgm- 163  Caenorhabdit...
Q05017        1097 VAALGDS-------LTLAMGarpsnssdppm----fwrglswsiggDGALethtt----lpniLKKFN-PSILGFSt--- 1157 rabbit
Q05017         741 VAALGDS-------LTAGIGigskpndlsdgt--tqyrglsyssggDGSLdnvtt----lpniLRQFN-SNLMGFAvgtg 806  rabbit
Q05017         394 IGAMGDS-------LTAGNGagsqpgnildvl--tqyrglswsvggDQNIstvtt----laniLREFN-PSLQGFSvgt- 458  rabbit
KIO51099        74 IVHIGDShiqsdlmTNEVRKnlqqkfgnagrglvfpyqlaktngsyNERFysnraw--esyrnIHPYK-NVPVGLSgial 150 
Q9KZR1         239 VVAFGDS-------ITDGAR--------------------------SQSDanhr-----wtdvLAARL-HEAAGDGr--- 276  Streptomyces...
WP_010912169   215 VIAIGDS-------ITDG----------------------------NGATldadn---rwpdvLAERLvSKQVSVL---- 252  Mesorhizobium
5W7C_D         168 yl--rlwkrnHCNHrdYQNISR---NGASSRN--------------------------LKKFIESLSRNK---------- 206  human
jgi:Fjoh_0246  151 wrdtggfvmeMSVKdaAYKFNTiqiITPKNENmfdlasgsqtkfvetterkvithkikKGEAISVIADKYdvsvaeikra 230 
Q9RDP5         112 ----------AAEH--SWNYAV---TGAR-----------------------------MADLTAQVTRA----------- 136  Streptomyces...
Q9N4P5         164 -------gskRALPdyQFNVAE---IGAETEDlpqq------------------alelVHRIQRYIGRS----------- 204  Caenorhabdit...
Q05017        1158 ---------gTLEGtmGLNVAV---QGARAQDmp----------------------aqARDLVERMRNSPei-------- 1195 rabbit
Q05017         807 -------dasGTNA--FFNQAV---PGAKARDlm----------------------sqVQTLVQRMKDDHrv-------- 844  rabbit
Q05017         459 --------grETTSqaFFNQAV---AGARADGli----------------------pqAQRLVALMKNDTri-------- 497  rabbit
KIO51099       151 wrdaggfaveLNIKdtAYRFNTihiVTPKNENmfdlatssqtktiqsterkvithkikKGEAISTIADKYnisvaeikrd 230 
Q9KZR1         277 ----------DTPRysVVNEGI---SGNRLLTsrpgr-----------------padnPSGLSRFQRDVL---------- 316  Streptomyces...
WP_010912169   253 ------------------NAGI---SGARLLDda----------------------mgVKASARFNRDVL---------- 279  Mesorhizobium
5W7C_D         207 ------------------VLDYPA------IVIYAMIGNDVCSGKsdpv---pamTTPEKLYSNVMQTLKHLNSHLPNgs 259  human
jgi:Fjoh_0246  231 nqlksnniragrilkiptNQTQPKniktseFVPLNLESDAFCHYYksekaldrifLIPNKEAKDFELNGLVLEKNAPG-- 308 
Q9RDP5         137 ------------------AQREPE------LVAVMAGANDACRSTts------amTPVADFRAQFEEAMATLRKKLPKaq 186  Streptomyces...
Q9N4P5         205 ------------------LKNKWA------LITIVTGSEEFCE------------KCEPPSRTSIRRALGVLRRGLPR-- 246  Caenorhabdit...
Q05017        1196 -----------------dLEKDWK------LVTLFVGGNDLCHFCenp-----egSSEGEYVQHIQQALDVLYEELPR-- 1245 rabbit
Q05017         845 -----------------nFQEDWK------VITVQIGASDLCDYCtds-----nlYSAANFYDHLRDALDALHREVPR-- 894  rabbit
Q05017         498 -----------------nFQEDWK------IITVFIGGNDLCDFCndp-----vrYSPQNFTDNIGTALDILHAEIPRaf 549  rabbit
KIO51099       231 nhlksnniragrtlkivtNETRPKnitsseFVSLDLESDSFTHSYhsdkasdkiyLIPNKNADKYELNGIILEKDAPG-- 308 
Q9KZR1         317 ------------------ERTNVK------AVVVVLGVNDVLN------------SPELADRDAILTGLRTLVDRAHA-- 358  Streptomyces...
WP_010912169   280 ------------------AQPGVK------AVILLIGINDISWP-----------GTPFAPEKSLPSLAALTTGYLQL-- 322  Mesorhizobium
5W7C_D         260 hvilygLpdgtflwdNLHNRYHPLGQLnkDMTYaqlysflnclq--vspchgwmssnKTLRTLTSERAEQLSNTLKKIAA 337  human
jgi:Fjoh_0246  309 ------ItysgigvnGAKFSDYNKYPLffEQLKalhpdlli---------fslgtneSFDKLEASEYIRRLREFIKNIKE 373 
Q9RDP5         187 vy-vssIpdlkrlwsQGRTNPLGKQVWklGLCPsmlgdadsl-------dsaatlrrNTVRDRVADYNEVLREVCAKDRR 258  Streptomyces...
Q9N4P5         247 ------------------ALIVLLGPVhvASTYrqninl------------mrprckCLEKMTGSNYRKLFDVWKRYFVE 296  Caenorhabdit...
Q05017        1246 ------Tfv----nvVEVMELAGLHQDqgGRCAtllaaqshctcfkysqssvemqelKKVNWNLQSGLSRLSYSHQYVQR 1315 rabbit
Q05017         895 ------Alv----nlVDFMNPSVTRQVflGNPDkcpvqqasalcncvlsprensyelARLEALAQAYQSSLRELVESGRY 964  rabbit
Q05017         550 vnlvkvLeisklrelYQETKVSCPRMIlrSLCPcvlkfd------------dnsteiASLIETIKEYQERTQQLIDSGRY 617  rabbit
KIO51099       309 ------LmysnigvnGAKFSDYNKYPLffEQLKalhpdlll---------fslgtneSYDHMEAAAYISELRKFISNIKA 373 
Q9KZR1         359 ---------------------RGLRVVgaTITPfg--------------------gyGGYTEARETMRQEVNEEIRSGRV 397  Streptomyces...
WP_010912169   323 ---------------AAQAHAHNLIIVggTLTPfegals-------------gtpldAYYTPEKEALRQKVNNWIRTSGA 374  Mesorhizobium
5W7C_D         338 Sek---------------ftNFNLFYMDF----------------AFHEIIQEWQKRGGQpwqliepvDGFHPNEVALLL 386  human
jgi:Fjoh_0246  374 QninvpiivmtsppslfrgrKPNHFVGEYaqrindiaekdgfavwDLYDELGGLSGIGQLkaegligkDWVHYSKKGYEK 453 
Q9RDP5         259 Cr-----------------sDDGAVh-------------------EFRFGTDQLSHw-----------DWFHPSVDGQAR 291  Streptomyces...
Q9N4P5         297 Fe-----------------tEFNVDNGTFg---------------VLSIPSLAIHS---RnpqtllvpGKPLLNRKGHSY 341  Caenorhabdit...
Q05017        1316 E-------------------DFAVVVQPF-----------------FQNTLVPLNGRGDTdltf-fsdDCFHFSERGHAE 1358 rabbit
Q05017         965 Dtr----------------eDFSVVLQPFf--------------hSIQLPVLQDGRLDTSff----apDCVHPNQKFHSQ 1010 rabbit
Q05017         618 Dtr----------------dDFTVVLQPF-----------------FEKVNMPKTQDGLPdnsf-fapDCFHFSSKAHAH 663  rabbit
KIO51099       374 QnievpiivmtpppsllkarKPNVYVRDYakaiieaaqtdgfavwDLYNEFGGFDGIRSLkatgligpDWVHYSKKGYEK 453 
Q9KZR1         398 F--------------------DTVVDFDKal-------------rDPYDPRRMRSDYDSG--------DHLHPGDKGYAR 436  Streptomyces...
WP_010912169   375 F--------------------DAVVDFDLll-------------rDPLHPTRLLPEFDSG--------DHLHPGDKGNRA 413  Mesorhizobium
5W7C_D         387 LADHF 391  human
jgi:Fjoh_0246  454 QGSLF 458 
Q9RDP5         292 LAEIA 296  Streptomyces coelicolor
Q9N4P5         342 AAKWL 346  Caenorhabditis elegans
Q05017        1359 MAIAL 1363 rabbit
Q05017        1011 LSRAL 1015 rabbit
Q05017         664 AASAL 668  rabbit
KIO51099       454 QGNLF 458 
Q9KZR1         437 MGAVI 441  Streptomyces coelicolor
WP_010912169   414 MAEAI 418  Mesorhizobium
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