1MJH,3IDF,1TQ8,3CIS,3DLO


Conserved Protein Domain Family
Usp

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pfam00582: Usp 
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Universal stress protein family
The universal stress protein UspA is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. UspA enhances the rate of cell survival during prolonged exposure to such conditions, and may provide a general "stress endurance" activity. The crystal structure of Haemophilus influenzae UspA reveals an alpha/beta fold similar to that of the Methanococcus jannaschii MJ0577 protein, which binds ATP, though UspA lacks ATP-binding activity.
Statistics
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Aligned: 169 rows
Threshold Bit Score: 50.8624
Threshold Setting Gi: 81772960
Created: 23-Apr-2019
Updated: 18-Jul-2019
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
1MJH_A   5 YKKILYPTDFSETAE-IALKHVKA---FKTL-KAEEVILLHVIDEREikkrdifslLLGVAGLNKSVEEFENELknkltE 79  Methanocaldococcus ja...
P72937 154 WRNLLVPYDASSAGN-YLIERLKS---ALEKaPPGKVESCYFLSILE---------DGMRRPELLEIRRQEAEA-----K 215 Synechocystis sp. PCC...
Q9HW73   3 LHNLLVVVDPSSDEQ-PALTRAQWi----AE-HSGASVELLLCDFNP---------ALDGGLFFDSHSLQRARD-----L 62  Pseudomonas aeruginosa
P44195   3 FKNILVVLNPSNEKQ-YALARAVRlveEQKN-ETKVKITALLSVYDL---------SYEMSALLSSEERSEMHQ-----Q 66  Haemophilus influenza...
Q8ZP84   4 YQNMLVVIDPNQDDQ-PALRRAVY---LHQR-IGGKIKAFLPIYDFS---------YEMTTLLSPDERTAMRQG-----V 64  Salmonella enterica s...
O30112   6 RGRVILVI-DDTDCGrVAAERLVF---MARAgFRGDVFVVFGKDIEI---------SPIASYEKEMKIYTSLRV-----K 67  Archaeoglobus fulgidus
Q9YFW0 163 FRKILVGA-DRNTSK-SMIDYAVN---AAST-DDGKVILAHIIEPPL---------EEPSYEVKNVFKYGEKAG-----E 222 Aeropyrum pernix
O67136   3 FNRIIVGIDGSPASL-IATRHAFK---IGKH-FDIPVIGMYVIDERL---------MDESFLLDLSSILGFTFY-----P 63  Aquifex aeolicus
Q8YWH9   1 mKNILLCTDGSAYAE-NVYRYGAWfasQFHAk----INVLFVTDIRS---------QKVVSTGNLSGSIGLGAS-----E 61  Nostoc sp. PCC 7120
Q8NLF3 168 VTRVNYAFTNESDDFeQGLRSSAE---LATN-WNVP---LRILAFSP---------TGITSAPTSRSLDISTEL-----S 226 Corynebacterium gluta...
1MJH_A  80 EAKNKMEN------------------IKKELEDVGFKVKDIIVVGIPHEEIVKIAEDEGVDIIIMGSHG-KTNLKEIL-- 138 Methanocaldococcus ja...
P72937 216 LAEIK-------------------------QQFSPLVPNIITEVRHGSPVQEILDTAFVNDITAIAVASrRATLLDWT-- 268 Synechocystis sp. PCC...
Q9HW73  63 YLDERVTWle--------------qlSMPLQQAGIRTQVEAQWGKPLDRMVLQRVGETRPDLVLKSTRK-HNLLRRLL-- 125 Pseudomonas aeruginosa
P44195  67 VIEKHRHAvq--------------yyLDKYANPEIELQSHIVWNSNEADAINEEVENNNYDLVVKYTKD-EEKLTSLI-- 129 Haemophilus influenza...
Q8ZP84  65 ISQRTAWIre---------------qAKYYLEAGVPIEIKVVWHNRPFEAIIQEVIAGSHDLVLKMAHQ-HDRLEAVI-- 126 Salmonella enterica s...
O30112  68 ASKFVEFY------------------RERLEEAGLEVKQVKIILGNVSEEVLRLEKLLNPDLIVFGMEK-RGFLKRLL-- 126 Archaeoglobus fulgidus
Q9YFW0 223 ER--------------------------------GVEVEIVVARGRPDKMLTAIASQMDASSVLVGRTV-ERRLSELI-- 267 Aeropyrum pernix
O67136  64 GISARVKEfleeq--------gdlilKTFAEEGRKEGVKVSIVQVQGIPWQEIVKEADKEDLILIGKKG-KKLIKGVL-- 132 Aquifex aeolicus
Q8YWH9  62 QLLNELVNlehekaklnnqraklilqNAAATLKAEGIEDFKLTNKTGFLVDCFHEFAENHDLIVLGKRG---EAADFAsg 138 Nostoc sp. PCC 7120
Q8NLF3 227 SEWRELTLamld-----------rarDGVLTDHPNLSVSSETGSGWGWSGAIDALRWKKGDLLCMGSHR-TDTLSRVF-- 292 Corynebacterium gluta...
1MJH_A 139 -LGSVTENVIKKSNKPVLVVK 158 Methanocaldococcus jannaschii DSM 2661
P72937 269 -VPSLTDSILNRSWFPLLFFS 288 Synechocystis sp. PCC 6803
Q9HW73 126 -LGNSDWQLIRHCPQPLWLVH 145 Pseudomonas aeruginosa
P44195 130 -FTPIDWQLLRKCPIPVLMVR 149 Haemophilus influenzae Rd KW20
Q8ZP84 127 -FTPTDWHLLRKCPSPVWMVK 146 Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
O30112 127 -RGDPYKEIIYETKAPVMVCK 146 Archaeoglobus fulgidus
Q9YFW0 268 -LGSTLDRLMTLCELPLIVYP 287 Aeropyrum pernix
O67136 133 -VSSNAENVARNAPCPVFMFP 152 Aquifex aeolicus
Q8YWH9 139 hLGANLDRIIRSSSKPCLVTP 159 Nostoc sp. PCC 7120
Q8NLF3 293 -VGSETMEIIRNSPVPTIIYP 312 Corynebacterium glutamicum
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