1MJH,3MT0,3CIS,1TQ8,3DLO,4R2K,3IDF


Conserved Protein Domain Family
Usp

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pfam00582: Usp 
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Universal stress protein family
The universal stress protein UspA is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. UspA enhances the rate of cell survival during prolonged exposure to such conditions, and may provide a general "stress endurance" activity. The crystal structure of Haemophilus influenzae UspA reveals an alpha/beta fold similar to that of the Methanococcus jannaschii MJ0577 protein, which binds ATP, though UspA lacks ATP-binding activity.
Statistics
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PSSM-Id: 306953
View PSSM: pfam00582
Aligned: 164 rows
Threshold Bit Score: 50.4774
Threshold Setting Gi: 74569972
Created: 13-Jul-2016
Updated: 4-Aug-2016
Structure
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Program:
Drawing:
Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
1MJH_A   5 YKKILYPTDFSETAE-IALKHVKA---FKTL-KAEEVILLHVIDEREIKKRDIFSLLLGVAGLNKSVEEFENElknklte 79  Methanocaldococcus ja...
Q9YFW0 163 FRKILVGA-DRNTSK-SMIDYAVN---AAST-DDGKVILAHIIEPPLEEPSYEVKNVFKYGEKAGEER------------ 224 Aeropyrum pernix
P72937 154 WRNLLVPYDASSAGN-YLIERLKS---ALEKaPPGKVESCYFLSILEDGMRRPELLEIRRQEAEAKLAEIK--------- 220 Synechocystis sp. PCC...
Q8NLF3 168 VTRVNYAFTNESDDFeQGLRSSAE---LATN-WNVP---LRILAFSPTGITSAPTSRSLDISTELSSEWRELTlamld-- 238 Corynebacterium gluta...
P9WLB5   1 -mTIVVGYLAGKVGP-SALHLAVR---VARM-HKTSLTVATIVRRHWPTPSLARVDAEYELWSEQLAAASAREaqr---- 70  Mycobacterium tubercu...
Q9HW73   3 LHNLLVVVDPSSDEQ-PALTRAQWi----AE-HSGASVELLLCDFNPALDGGLFFDSHSLQRARDLYLDERVTwleq--- 73  Pseudomonas aeruginosa
P44195   3 FKNILVVLNPSNEKQ-YALARAVRlveEQKN-ETKVKITALLSVYDLSYEMSALLSSEERSEMHQQVIEKHRHavqy--- 77  Haemophilus influenza...
Q8R869 250 NEKIMVCITPNPLSK-KLIRRGAR---RARR-FKCDWVVVYVDCTHFLAPKLTEKDKEVLESHFMLAK------------ 312 Caldanaerobacter subt...
O28746   1 mERILLVL-DDTGRGeIAFQKLKK---LAEDgLRGEVYILYIREMEVPPFVPEEKELAAYHRLMTQSMKKLEGfk----- 71  Archaeoglobus fulgidus
O30112   6 RGRVILVI-DDTDCGrVAAERLVF---MARAgFRGDVFVVFGKDIEISPIASYEKEMKIYTSLRVKASKFVEFyr----- 76  Archaeoglobus fulgidus
1MJH_A  80 eaknkmenikKELEDVGFKVKDIIVVGIPHEEIVKIAEDEGVDIIIMGSHG-KTNLKEIL---LGS-VTENVIKKSNK-P 153 Methanocaldococcus ja...
Q9YFW0 225 ----------------GVEVEIVVARGRPDKMLTAIASQMDASSVLVGRTV-ERRLSELI---LGS-TLDRLMTLCEL-P 282 Aeropyrum pernix
P72937 221 ------------QQFSPLVPNIITEVRHGSPVQEILDTAFVNDITAIAVASrRATLLDWT---VPS-LTDSILNRSWF-P 283 Synechocystis sp. PCC...
Q8NLF3 239 -----rardgVLTDHPNLSVSSETGSGWGWSGAIDALRWKKGDLLCMGSHR-TDTLSRVF---VGS-ETMEIIRNSPV-P 307 Corynebacterium gluta...
P9WLB5  71 --------ylRRLADGIEVSYHHRAHRSVSAGLLDVVEELEAEVLVLGSFP-SGRRARVL---IGS-TADRLLHSSPV-P 136 Mycobacterium tubercu...
Q9HW73  74 -------lsmPLQQAGIRTQVEAQWGKPLDRMVLQRVGETRPDLVLKSTRK-HNLLRRLL---LGN-SDWQLIRHCPQ-P 140 Pseudomonas aeruginosa
P44195  78 -------yldKYANPEIELQSHIVWNSNEADAINEEVENNNYDLVVKYTKD-EEKLTSLI---FTP-IDWQLLRKCPI-P 144 Haemophilus influenza...
Q8R869 313 ---------------QLGAEVYTLRGKSVSDELLKFAKKMHITQIIIGHSQ-RSWLQTLF---RGS-TVIKLIKKAKNiE 372 Caldanaerobacter subt...
O28746  72 ---------nQLEKAGLKVSDVSVVFGKYADRLLLVEKQIKPDLIVVGFKG--GLLKRVIggfFGKdPCEVLLKKSKA-S 139 Archaeoglobus fulgidus
O30112  77 ---------eRLEEAGLEVKQVKIILGNVSEEVLRLEKLLNPDLIVFGMEK-RGFLKRLL---RGD-PYKEIIYETKA-P 141 Archaeoglobus fulgidus
1MJH_A 154 VLVVK 158 Methanocaldococcus jannaschii
Q9YFW0 283 LIVYP 287 Aeropyrum pernix
P72937 284 LLFFS 288 Synechocystis sp. PCC 6803
Q8NLF3 308 TIIYP 312 Corynebacterium glutamicum
P9WLB5 137 VAITP 141 Mycobacterium tuberculosis H37Rv
Q9HW73 141 LWLVH 145 Pseudomonas aeruginosa
P44195 145 VLMVR 149 Haemophilus influenzae Rd KW20
Q8R869 373 IHVIP 377 Caldanaerobacter subterraneus subsp. tengcongensis
O28746 140 LLICR 144 Archaeoglobus fulgidus
O30112 142 VMVCK 146 Archaeoglobus fulgidus
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